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  1. 9581
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    Role and mechanism of circ-PRKCI in hepatocellular carcinoma
  2. 9582
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    Deep south-north genetic divergence in Godlewski’s bunting (Emberiza godlewskii) related to uplift of the Qinghai-Tibet Plateau and habitat preferences
  3. 9583
    “…The pyrin inflammasome also plays a role in mediating inflammation in other autoinflammatory diseases linked to dysregulation in the actin polymerization pathway. …”
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    The Pyrin Inflammasome in Health and Disease
  4. 9584
    por Parrell, Benjamin, Lammert, Adam C.
    Publicado 2019
    “…Current models of speech motor control rely on either trajectory-based control (DIVA, GEPPETO, ACT) or a dynamical systems approach based on feedback control (Task Dynamics, FACTS). …”
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    Bridging Dynamical Systems and Optimal Trajectory Approaches to Speech Motor Control With Dynamic Movement Primitives
  5. 9585
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    The Impact of Diet on the Involvement of Non-Coding RNAs, Extracellular Vesicles, and Gut Microbiome-Virome in Colorectal Cancer Initiation and Progression
  6. 9586
    “…T-tubule remodelling in cardiac diseases is associated with downregulation of JPH2 expression suggesting that JPH2 plays a crucial role in T-tubule stability. Furthermore, increasing evidence indicate that JPH2 might additionally act as a modulator of calcium signalling by directly regulating RyR and LTCCs. …”
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    Junctophilin-2 tethers T-tubules and recruits functional L-type calcium channels to lipid rafts in adult cardiomyocytes
  7. 9587
    “…Background: In surgical correction of adult spinal deformity (ASD), pelvic incidence (PI)-lumbar lordosis (LL) plays a key role to restore normal sagittal alignment. …”
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    Optimized Surgical Strategy for Adult Spinal Deformity: Quantitative Lordosis Correction versus Lordosis Morphology
  8. 9588
    “…These oligopeptides are known to act as metabolic inhibitors (e.g., in chemical defence against grazers, parasites) and allow a competitive advantage. …”
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    Toxins and Other Bioactive Metabolites in Deep Chlorophyll Layers Containing the Cyanobacteria Planktothrix cf. isothrix in Two Georgian Bay Embayments, Lake Huron
  9. 9589
    “…EOLC plays a very critical role in ensuring that terminally ill patients are given a proper and adequate amount of care. …”
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    The end-of-life care in the emergency department setting with respect to the Middle East countries and comparison with the Western countries
  10. 9590
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    Acute Effects of Esports on the Cardiovascular System and Energy Expenditure in Amateur Esports Players
  11. 9591
    “…BACKGROUND: Eosinophils act as a secondary antigen-presenting cell (APC) to stimulate Th cell responses against antigens. …”
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    Role of IL-25 on Eosinophils in the Initiation of Th2 Responses in Allergic Asthma
  12. 9592
    “…BACKGROUND: Cognitive impairment is a core feature of disorders on the schizophrenia-bipolar spectrum, i.e., schizophrenia, bipolar disorder, and schizoaffective disorder. …”
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    Brain Derived Neurotrophic Factor and Cognitive Dysfunction in the Schizophrenia-Bipolar Spectrum: A Systematic Review and Meta-Analysis
  13. 9593
    “…The placenta is an important organ that maintains a healthy pregnancy by transporting nutrients to the fetus and removing waste from the fetus. It also acts as a barrier to protect the fetus from hazardous materials. …”
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    Dietary Antioxidant Curcumin Mitigates CuO Nanoparticle-Induced Cytotoxicity through the Oxidative Stress Pathway in Human Placental Cells
  14. 9594
    por Varghese, Sneha S., Dhawan, Sangeeta
    Publicado 2023
    “…Cellular senescence is a complex process marked by permanent cell-cycle arrest in response to a variety of stressors, and acts as a safeguard against the proliferation of damaged cells. …”
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    Senescence: a double-edged sword in beta-cell health and failure?
  15. 9595
    “…In addition, SlPLATZ1 was found to play an important role in salt stress. …”
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    Genome-Wide Identification and Expression Analysis of the PLATZ Transcription Factor in Tomato
  16. 9596
    “…Glycosyltransferases from the GRAS organisms Bacillus megaterium (SacB) and Aspergillus niger (Suc1) were used in this study. Substrate engineering of these glycosyltransferases generally acting on sucrose leads to the controlled formation of novel tailored di-, tri- and tetrasaccharides. …”
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    Chemo-enzymatic synthesis and in vitro cytokine profiling of tailor-made oligofructosides
  17. 9597
    “…In the recent past, it has repeatedly been reported that CD4 cells play an important role in the immunology of chronic myeloid leukaemia. …”
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    Tumor Protective Activity of CD4+ but Not of CD8+ T Cells in DNA-Vaccinated Mice Challenged with bcr-abl-Transformed Cells
  18. 9598
    “…Parkinson disease is a debilitating and incurable neurodegenerative disorder affecting ∼1–2% of people over 65 years of age. Oxidative damage is considered to play a central role in the progression of Parkinson disease and strong evidence links chronic exposure to the pesticide paraquat with the incidence of the disease, most probably through the generation of oxidative damage. …”
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    Superoxide Dismutase (SOD)-mimetic M40403 Is Protective in Cell and Fly Models of Paraquat Toxicity: IMPLICATIONS FOR PARKINSON DISEASE
  19. 9599
    “…In this study, we report that neutrophils constitutively express various Src family isoforms (STKs), as well as Syk, and that inhibition of these protein tyrosine kinases selectively hinders inflammatory cytokine generation by acting posttranscriptionally. Accordingly, STK or Syk inhibition decreases the phosphorylation of signaling intermediates (e.g., eIF-4E, S6K, and MNK1) involved in translational control. …”
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    Regulation of Discrete Functional Responses by Syk and Src Family Tyrosine Kinases in Human Neutrophils
  20. 9600
    “…Lhx4 inactivation ablates Bhlhe23 expression, whereas overexpression of Bhlhe23 partially rescues RBC development in the absence of Lhx4. Thus, by acting upstream of Bhlhe23, Prdm8, Fezf2, Lhx3, and other BC genes, Lhx4, together with Isl1, could play essential roles in regulating the subtype-specific development of RBCs and CBCs.…”
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    LIM-Homeodomain Transcription Factor LHX4 Is Required for the Differentiation of Retinal Rod Bipolar Cells and OFF-Cone Bipolar Subtypes
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