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  1. 961
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    Play Active physical activity policy intervention and implementation support in early childhood education and care: results from a pragmatic cluster randomised trial
  2. 962
    “…We found that Meth plays a direct role by regulating the abundance and nuclear translocation of transcription factors with binding sites in the CCR5 promoter. …”
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    Dopamine and its receptors play a role in the modulation of CCR5 expression in innate immune cells following exposure to Methamphetamine: Implications to HIV infection
  3. 963
    “…Our results demonstrate that hepcidin knockdown protected N27 cells from 6-OHDA induced apoptosis and that hepcidin plays a major role in reducing cellular iron burden and oxidative damage by possibly regulating cellular iron export mediated by ferroportin 1.…”
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    Hepcidin Plays a Key Role in 6-OHDA Induced Iron Overload and Apoptotic Cell Death in a Cell Culture Model of Parkinson's Disease
  4. 964
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    Analyses of key genes involved in Arctic adaptation in polar bears suggest selection on both standing variation and de novo mutations played an important role
  5. 965
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    Plasmid-encoded NP73-102 modulates atrial natriuretic peptide receptor signaling and plays a critical role in inducing tolerogenic dendritic cells
  6. 966
    “…Rolling-circle replication of streptococcal plasmid pMV158 is controlled by the concerted action of two trans-acting elements, namely transcriptional repressor CopG and antisense RNAII, which inhibit expression of the repB gene encoding the replication initiator protein. …”
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    The 5′-tail of antisense RNAII of pMV158 plays a critical role in binding to the target mRNA and in translation inhibition of repB
  7. 967
    “…The present study evaluates the effectiveness of the Active Play in ASP intervention—a program for ASP staff aimed at supporting physical activity among first graders in ASP. …”
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    Active play in ASP –a matched-pair cluster-randomized trial investigating the effectiveness of an intervention in after-school programs for supporting children’s physical activity
  8. 968
    “…We show that the history of play in a population game contains exploitable information that can be successfully used by sophisticated strategies to defeat memory-one opponents, including zero determinant strategies. …”
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    The Art of War: Beyond Memory-one Strategies in Population Games
  9. 969
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    Acting like a Tough Guy: Violent-Sexist Video Games, Identification with Game Characters, Masculine Beliefs, & Empathy for Female Violence Victims
  10. 970
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    To what extent do primary care practice nurses act as case managers lifestyle counselling regarding weight management? A systematic review
  11. 971
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    Nuclear corepressor SMRT acts as a strong regulator of both β-oxidation and suppressor of fibrosis in the differentiation process of mouse skeletal muscle cells
  12. 972
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    LmABCB3, an atypical mitochondrial ABC transporter essential for Leishmania major virulence, acts in heme and cytosolic iron/sulfur clusters biogenesis
  13. 973
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    Systematically Characterizing Chemical Profile and Potential Mechanisms of Qingre Lidan Decoction Acting on Cholelithiasis by Integrating UHPLC-QTOF-MS and Network Target Analysis
  14. 974
    por Hemida, Maged Gomaa
    Publicado 2019
    “…MERS-CoV is considered an ideal example of the One Health concept. This is due to the animals, especially dromedary camels, play important roles in the transmission and sustainability of the virus, and the virus can be transmitted through aerosols of infected patients into the environment. …”
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    Middle East Respiratory Syndrome Coronavirus and the One Health concept
  15. 975
    “…Furthermore, it also regulates the NF-κB signaling pathway by blocking IKK and p65 activation and IκB degradation. DL0309 also acts as a non-selective COX inhibitor in glial cells. …”
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    Methyl salicylate 2-O-β-D-lactoside, a novel salicylic acid analogue, acts as an anti-inflammatory agent on microglia and astrocytes
  16. 976
    por Soda, Kuniyasu
    Publicado 2018
    “…Recent investigations have revealed that changes in DNA methylation status play an important role in aging-associated pathologies and lifespan. …”
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    Polyamine Metabolism and Gene Methylation in Conjunction with One-Carbon Metabolism
  17. 977
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    The Na,K-ATPase acts upstream of phosphoinositide PI(4,5)P(2) facilitating unconventional secretion of Fibroblast Growth Factor 2
  18. 978
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    Reduced Levels of miR–28 and miR–200a Act as Predictor Biomarkers of Aggressive Clinicopathological Characteristics in Gastric Cancer Patients
  19. 979
    “…Mechanistically, hsa_circRNA_0088036 could directly interact with miR-140-3p and act as a miRNA sponge to modulate FOXQ1 expression. …”
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    Hsa_circRNA_0088036 acts as a ceRNA to promote bladder cancer progression by sponging miR-140-3p
  20. 980
    “…Keratinocytes play an essential role during psoriasis development, and they express high levels of β(2)-Adrenergic receptor (β(2)-AR), which increases intracellular cAMP levels when activated. …”
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    Long-Acting β(2) Adrenergic Receptor Agonist Ameliorates Imiquimod-Induced Psoriasis-Like Skin Lesion by Regulating Keratinocyte Proliferation and Apoptosis
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