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  1. 9781
    “…CONCLUSION: The study results highlight parental challenges regarding childhood disabilities and severe health conditions, as well as communication and ethical aspects regarding to act in the best interests of the child. Parents played a vital role in interpreting their child with Down syndrome. …”
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    Participation, challenges and needs in children with down syndrome during cancer treatment at hospital: a qualitative study of parents' experiences
  2. 9782
    “…ChIP-Seq for FXR revealed binding peaks in the heme biosynthesis genes, Alas1, Alad, Uros, and Fech, suggesting that FXR may act as a transcription factor for these genes. …”
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    Investigating the Role of Farnesoid X Receptor in Heme Biosynthesis and Ductular Reaction
  3. 9783
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    Childhood and adolescent predictors of leisure time physical activity during the transition from adolescence to adulthood: a population based cohort study
  4. 9784
    “…RESULTS: Combination treatments of α-TEA plus DOXO or CDDP act cooperatively to induce apoptosis, caspase-8 and caspase-9 cleavage, p73, phospho-c-Ab1 and phospho-JNK protein expression, and increase expression of p53 downstream mediators; namely, death receptor-5, CD95/APO-1 (Fas), Bax and Noxa, as well as Yap nuclear translocation - plus reduce expression of Bcl-2. …”
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    α-TEA cooperates with chemotherapeutic agents to induce apoptosis of p53 mutant, triple-negative human breast cancer cells via activating p73
  5. 9785
    “…Thus, MecA actually acts as an anti-sigma factor to regulate the stability of SigX during competence development.…”
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    Regulated proteolysis of the alternative sigma factor SigX in Streptococcus mutans: implication in the escape from competence
  6. 9786
    “…Because of the high correlations of superoxide dismutase 2 with pleural effusion interferon gamma and tumor necrosis factor alpha levels, this marker may act as an inflammatory factor that plays an important role in the development of tuberculous pleural effusion.…”
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    Superoxide dismutase 2 as a marker to differentiate tuberculous pleural effusions from malignant pleural effusions
  7. 9787
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    Changes in weight, physical activity, sedentary behaviour and dietary intake during the transition to higher education: a prospective study
  8. 9788
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    Inhibition of miR-9-5p suppresses prostate cancer progress by targeting StarD13
  9. 9789
    “…ABSTRACT: Oxidative stress plays a crucial role in the development of age-related neurodegenerative diseases. …”
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    Neuroprotective Effects of Glochidion zeylanicum Leaf Extract against H(2)O(2)/Glutamate-Induced Toxicity in Cultured Neuronal Cells and Aβ-Induced Toxicity in Caenorhabditis elegans
  10. 9790
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    No Correlation Between Plantar Flexor Muscle Volume and Sprint Performance in Sprinters
  11. 9791
    por Inazu, Masato
    Publicado 2019
    “…CTL2 is also highly expressed in mitochondria and may be involved in the oxidative pathway of choline metabolism. Therefore, CTL1- and CTL2-mediated choline transport to the brain through the blood–brain barrier plays an essential role in various functions of the central nervous system by acting as the rate-limiting step of cholinergic neuronal activity.…”
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    Functional Expression of Choline Transporters in the Blood–Brain Barrier
  12. 9792
    “…We functionally characterized four FLC homologues (BrrFLC1, FLC2, FLC3, and FLC5), and found that BrrFLC2 and BrrFLC1 play a major role in repressing flowering in turnip and in transgenic Arabidopsis. …”
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    Effect of vernalization on tuberization and flowering in the Tibetan turnip is associated with changes in the expression of FLC homologues
  13. 9793
    “…CRBP-1 plays a major role in wound healing and arterial tissue remodelling processes. …”
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    Vitamin A, Cancer Treatment and Prevention: The New Role of Cellular Retinol Binding Proteins
  14. 9794
    “…Detailed analyses of the simulation results indicate that E297(6.58) and I294(6.55) play crucial roles in the rotation of TM6. …”
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    Molecular switches of the κ opioid receptor triggered by 6′-GNTI and 5′-GNTI
  15. 9795
    “…Interestingly, mutants of AtTOP3A and AtRMI1 are also sterile due to extensive chromosome breakage in meiosis I, a phenotype that seems to be specific for plants. …”
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    The RTR complex as caretaker of genome stability and its unique meiotic function in plants
  16. 9796
    “…In particular, circulating exosomes from NAFLD patients are inflammatory drivers for HepaRG cells, acting through CB1R activation and the downregulation of CB2R. …”
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    Plasma-Derived Exosomes from NAFLD Patients Modulate the Cannabinoid Receptors’ Expression in Cultured HepaRG Cells
  17. 9797
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    FTX contributes to cell proliferation and migration in lung adenocarcinoma via targeting miR-335-5p/NUCB2 axis
  18. 9798
    “…Green tea, soybean, and guava bioactive substances are well-known to act as anti-inflammation, and antioxidants become prospective COVID-19 illness candidates to overcome the cytokine storm. …”
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    Inflammation inhibitory activity of green tea, soybean, and guava extracts during Sars-Cov-2 infection through TNF protein in cytokine storm
  19. 9799
    “…Plant DCL4 is involved in the biogenesis of either functional endogenous or exogenous (i.e. viral) short interfering (si)RNAs, thus playing crucial antiviral roles. …”
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    Exogenous and endogenous dsRNAs perceived by plant Dicer-like 4 protein in the RNAi-depleted cellular context
  20. 9800
    “…PURPOSE: Neutrophils act as a non-negligible regulator in the initiation and progression of malignancies, playing bifacial roles in the process. …”
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    Single-Cell Profiling of Tumor-Associated Neutrophils in Advanced Non-Small Cell Lung Cancer
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