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  1. 9881
    “…The endothelial cells (ECs) make up the inner lining of blood vessels, acting as a barrier separating the blood and the tissues in several organs. …”
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  2. 9882
  3. 9883
  4. 9884
  5. 9885
  6. 9886
    “…The spindle checkpoint acts as a mitotic surveillance system, monitoring interactions between kinetochores and spindle microtubules and ensuring high-fidelity chromosome segregation [1, 2, 3]. …”
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  7. 9887
  8. 9888
  9. 9889
  10. 9890
    por Glassford, William J., Rebeiz, Mark
    Publicado 2013
    “…Structural and functional constraints are known to play a major role in restricting the path of evolution of protein activities. …”
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  11. 9891
    “…RESULTS: Interphotoreceptor matrix (IPM) plays a crucial role in photoreceptors differentiation and acts as a mediator in interactions between photoreceptors and retinal pigment epithelium (RPE). …”
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  12. 9892
    “…This articulated universal mechanism is regulated through the cis-acting elements in an array of Nrf2 target genes called antioxidant response elements (AREs), which play a critical role in redox homeostasis. …”
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  13. 9893
    “…Using protein-protein interaction and luciferase assays we show that BCAS2 interacts with ERα both in vitro and in vivo and upregulates transcriptional activation of ERα directly through its N-terminal region (AF-1) and indirectly through its C-terminal (AF-2) region, acting in concert with AF-2 interacting coactivators. …”
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  14. 9894
    “…IL-33, a member of the IL-1 cytokine family has been shown to play a dual role within the body. …”
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  15. 9895
    “…UVB enhances the percentage of apoptotic keratinocytes, which can be caused by the increased prostaglandin generation by cyclooxygenase-2, or/and induced cannabinoid receptor 1/2 (CB1/2) expression. AEA used alone intensifies apoptosis by affecting caspase expression, and in UVB-irradiated keratinocytes, cyclooxygenase-2 activity is increased, while CBD acts as a cytoprotective when used with or without UVB. …”
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  16. 9896
  17. 9897
    “…While the sonic HH (SHH) pathway plays a major role in the development of the central nervous system, the desert HH (DHH) regulates the development of the gonads, and the indian HH (IHH) acts on the development of bones and joints. …”
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  18. 9898
  19. 9899
  20. 9900
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