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  1. 10421
    “…Consequently, we found that recombinant PTMP1 acts as a vWF domain by mediating cell adhesion, spreading, proliferation, and formation of actin cytoskeleton. …”
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    Recombinant mussel proximal thread matrix protein promotes osteoblast cell adhesion and proliferation
  2. 10422
    “…A total of 11 genes including CSF3, DKK1, FOSL1, FST, TERT, MMP13, PTHLH, SPRY2, TGFBR2, THBS1, and TIMP1 acted as main components of pathway associated with 2-fold down regulated genes. …”
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    Microarray Analysis of Gene Expression Alteration in Human Middle Ear Epithelial Cells Induced by Asian Sand Dust
  3. 10423
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    Self-care behaviors mediates the relationship between resilience and quality of life in breast cancer patients
  4. 10424
    “…Conclusion:PRP acts as a protective factor during flap I/R injury by reducing reactive oxygen species level and proinflammatory cytokines via decreased expression of pASK-1 and pNF-κB.…”
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    Effect of Platelet-Rich Plasma on Ischemia-Reperfusion Injury in a Skin Flap Mouse Model
  5. 10425
    “…N-(piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide, a CB(1) antagonist, prevents muscarine from inhibiting release and arachidonylcyclopropylamide (ACPA), a CB(1) receptor agonist, mimics M(3) activation and occludes the effect of muscarine. …”
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    Endocannabinoids mediate muscarine-induced synaptic depression at the vertebrate neuromuscular junction
  6. 10426
    “…MM-1α is a c-Myc-binding protein and acts as a transcriptional co-repressor in the nucleus. …”
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    Deficiency of spermatogenesis and reduced expression of spermatogenesis-related genes in prefoldin 5-mutant mice
  7. 10427
    “…We hypothesized that iNKT cells would play an important role in mediating the neonatal immune response to sepsis. …”
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    Activation of Invariant Natural Killer T Cells Redirects the Inflammatory Response in Neonatal Sepsis
  8. 10428
    “…This suggests that Pcc1, Kae1, and Bud32 are the core KEOPS components, and Cgi121 may play auxiliary roles. …”
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    Unraveling the Pathobiological Role of the Fungal KEOPS Complex in Cryptococcus neoformans
  9. 10429
    “…Catapol can enhance this effect; In the depression model, ROS, NLRP3, NF-κ B and iNOS were up-regulated Catalpol group MAPK, NF-κ Reduced expression of B and TLR4; ROS, caspase-1, IL-1β, IL-18 and iNOS protein increased. …”
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    Catalpol Alleviates Depression by Inhibiting NLRP3 Inflammasome via TLR4/MAPK/NF-Kb Pathway
  10. 10430
    “…Recently, adenosine has been demonstrated to play a critical role in protecting the embryo against hypoxia via adenosine A1 receptors (A1ARs), which are expressed in the heart, nervous system, and other sites during development. …”
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    Identification of the heart as the critical site of adenosine mediated embryo protection
  11. 10431
    “…A disintegrin and metalloprotease with thrombospondin type-1 motif (ADAMTS-1) is a secreted enzyme that acts on a wide variety of extracellular matrix (ECM) substrates associated with vascular diseases. …”
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    Effects of baicalin on collagen Ι and collagen ΙΙΙ expression in pulmonary arteries of rats with hypoxic pulmonary hypertension
  12. 10432
    “…[N33A]CXCL12 showed reduced potency both in Gα(i) coupling and β-arrestin recruitment as compared to the wild type chemokine, acting as an unbiased ligand. …”
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    A single amino acid substitution in CXCL12 confers functional selectivity at the beta-arrestin level
  13. 10433
    “…The lack of an effect in NSG mice supports the assumption that AZ acts by immunomodulation, which is known to play a role in ONC damage. …”
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    Neuroprotective Effect of Azithromycin Following Induction of Optic Nerve Crush in Wild Type and Immunodeficient Mice
  14. 10434
    “…On the contrary, they have much lower activity against the α-(1,2)-and α-(1,3)-double-substituted substrates than the single-substituted ones. …”
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    Arabinoxylo- and Arabino-Oligosaccharides-Specific α-L-Arabinofuranosidase GH51 Isozymes from the Amylolytic Yeast Saccharomycopsis fibuligera
  15. 10435
    “…Diazoxide also attenuated the decrease in contractility induced by simulated ischemia (1% O(2)). We conclude that hypoxia and T3 enhance the functionality of hESC-VCMs and their engineered tissues by selectively acting on sarc and mitoI(K, ATP).…”
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    Non-cell autonomous cues for enhanced functionality of human embryonic stem cell-derived cardiomyocytes via maturation of sarcolemmal and mitochondrial K(ATP) channels
  16. 10436
    por Yu, Dalin, Huang, Bin, Wu, Bin, Xiao, Jun
    Publicado 2021
    “…Adipose tissue acts as an active endocrine organ secreting a number of adipokines and may be involved in biological mechanism of stroke. …”
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    Association of serum vaspin, apelin, and visfatin levels and stroke risk in a Chinese case-control study
  17. 10437
    “…Methylation and demethylation of histone play a crucial role in regulating chromatin formation and gene expression. …”
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    Genome-wide identification of the jumonji C domain- containing histone demethylase gene family in wheat and their expression analysis under drought stress
  18. 10438
    “…Because programmed cell death pathways including necroptosis are important antiviral defense mechanisms in HSV1-associated peripheral diseases, they might also play critical roles in HSV1 neuropathogenesis. …”
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    RIPK3 and caspase 8 collaborate to limit herpes simplex encephalitis
  19. 10439
    “…Copper, a transition metal, is an essential component for normal growth and development. It acts as a critical co-factor of many enzymes that play key roles in diverse cellular processes. …”
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    Targeting of copper-trafficking chaperones causes gene-specific systemic pathology in Drosophila melanogaster: prospective expansion of mutational landscapes that regulate tumor resistance to cisplatin
  20. 10440
    “…The protumorigenic effects of BMP13 on HCC cells were almost completely abrogated by the small molecule dorsomorphin 1 (DMH1), which selectively blocks the intracellular kinase domain of ALK2 and ALK3, indicating that BMP13 acts via these BMP type I receptors on HCC cells. …”
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    Bone Morphogenetic Protein 13 Has Protumorigenic Effects on Hepatocellular Carcinoma Cells In Vitro
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