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  1. 10501
    “…Here, by using super‐ or naturally ovulated mouse models, we demonstrated for the first time that ovulation‐induced local inflammation acted as the driver for selective activation of surrounding primordial follicles in each estrous cycle. …”
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  2. 10502
  3. 10503
    “…In this study, we examined the functional roles that both CLIC4 and ROS play in the process of ovarian cancer cell-stimulated or TGF-β1 induced fibroblast-to-myofibroblast transdifferentiation. …”
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  4. 10504
    “…Sema3e is a novel inhibitor of osteoclast formation in vitro and may play a role in maintaining local bone homeostasis, potentially acting as a coupling factor between osteoclasts and osteoblasts.…”
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  5. 10505
  6. 10506
    “…Interestingly, many of these clusters appear to encode the biosynthesis of lipopeptides, which may play key roles in the diverse environments were rhodococci thrive, by acting as biosurfactants, pathogenicity factors or antimicrobials. …”
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  7. 10507
    “…BACKGROUND: Glucocorticoid hormones are known to play a key role in mediating a cascade of physiological responses to social and ecological stressors and can therefore influence animals’ behaviour and ultimately fitness. …”
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  8. 10508
    “…Herein, we introduce an isothermal enzyme-free concatenated hybridization chain reaction (C-HCR), in which the output of the upstream hybridization chain reaction (HCR-1) layer acts as an intermediate input to activate the downstream hybridization chain reaction (HCR-2) layer. …”
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  9. 10509
    “…Emerging evidence indicates that long noncoding RNAs (lncRNAs) play important roles in the regulation of cell differentiation by acting as competing endogenous RNA (ceRNA). …”
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  10. 10510
    por Dimitrova, Nevena
    Publicado 2020
    “…Accordingly, we argue that within early triadic interactions, the communicative function of infants’ eye gaze is shaped by the knowledge that the infant and the parent share on the socio-cultural use of the referent (i.e., the object). Importantly, before young children develop their ability to convey clear communicative functions, including with eye gaze, the interpretations and responses that parents provide to infants’ early communicative acts play a major role. …”
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  11. 10511
  12. 10512
  13. 10513
    “…Immunoreactions regulated by TAMs (Tumor-associated macrophages) play a pivotal role in tumorigenesis and metastasis. …”
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  14. 10514
    “…Using different extract concentrations, an IC(50) value of 15.74 µg mL(−1) was calculated for turmeric extract. Commercial curcumin inhibited the 3CL(Pro) activity, but did not fully account for the inhibitory effect of turmeric rhizomes extracts, suggesting that other components of the turmeric extract must also play a main role in inhibiting the 3CL(Pro) activity. …”
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  15. 10515
    “…The increase of the electrode separation distance acts similarly to the introduction of a semipermeable membrane toward the increase of the capacitor cycle life. …”
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  16. 10516
    por Baz, Mohammed
    Publicado 2022
    “…It is, therefore, not surprising that the IoT acts as a paramount infrastructure for most modern and envisaged systems, including but not limited to smart homes, e-health, and intelligent transportation systems. …”
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  17. 10517
    “…Sucrose non-fermentation-related protein kinase 1 (SnRK1) a Ser/Thr protein kinase, is known to play a crucial role in plants during biotic and abiotic stress responses by activating protein phosphorylation pathways. …”
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  18. 10518
    “…Microbial secondary metabolites play important roles in biotic interactions in microbial communities and yet, we do not understand how these compounds impact the assembly and development of microbial communities. …”
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  19. 10519
    “…AFF3 is located in nuclear speckles, which play an important role in RNA splicing. AFF3 overexpression in adrenocortical cells interferes with the organization and/or biogenesis of these nuclear speckles and alters the distribution of CDK9 and cyclin T1 such that they accumulate at the sites of AFF3/speckles. …”
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  20. 10520
    “…Moreover, the mutant Met122Ala showed much stronger substrate affinity and higher catalytic efficiency because less steric repulsion acted on the substrates. Taken together, these results showed that, in PE8, Arg79 and Met122 play important roles in substrate binding and the binding pocket shaping, respectively. …”
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