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10761por Aouidat, Fatima, Boumati, Sarah, Khan, Memona, Tielens, Frederik, Doan, Bich-Thuy, Spadavecchia, Jolanda“…In this article, it was reported for the first time, a novel synthesis of Gd(III)–biopolymer–Au(III) complex, acting as a key ingredient of core-shell gold nanoparticles (Gd(@AuNPs). …”
Publicado 2019
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10762por Wang, Xiaoyu, Liu, Xuming, An, Yong-qiang Charles, Zhang, Hongyu, Meng, Di, Jin, Yanan, Huo, Hongyan, Yu, Lili, Zhang, Jixing“…Glutathione peroxidases (GPXs) protect cells against damage caused by reactive oxygen species (ROS) and play key roles in regulating many biological processes. …”
Publicado 2021
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10763por Marathe, Gayatri, Moodie, Erica E M, Brouillette, Marie-Josée, Lanièce Delaunay, Charlotte, Cox, Joseph, Martel-Laferrière, Valérie, Gill, John, Cooper, Curtis, Pick, Neora, Vachon, Marie-Louise, Walmsley, Sharon, Klein, Marina B“…BACKGROUND: Depression is common in people with human immunodeficiency virus (HIV) and hepatitis C virus (HCV), with biological and psychosocial mechanisms at play. Direct acting antivirals (DAA) result in high rates of sustained virologic response (SVR), with minimal side-effects. …”
Publicado 2022
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10764“…In oocytes, MAPK is activated independently of growth factors and tyrosine kinase receptors, acts independently of transcriptional regulation, plays a crucial role in controlling meiotic divisions, and is under the control of a peculiar upstream regulator, the kinase Mos. …”
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10765por Huang, Haibo, Liu, An, Wu, Hui, Ansari, Abdur Rahman, Wang, Jixiang, Huang, Xiyao, Zhao, Xing, Peng, Kemei, Zhong, Juming, Liu, Huazhen“…CONCLUSIONS: STm and Salmonella LPS could induce acute chick thymic injury. LPS treatment acted faster than STm. TLR4-FOS/JUN pathway may play an important role in LPS induced chick thymic injury. …”
Publicado 2016
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10766por Armas-González, Estefanía, Domínguez-Luis, María Jesús, Díaz-Martín, Ana, Arce-Franco, Mayte, Castro-Hernández, Javier, Danelon, Gabriela, Hernández-Hernández, Vanesa, Bustabad-Reyes, Sagrario, Cantabrana, Alberto, Uguccioni, Mariagrazia, Díaz-González, Federico“…CONCLUSIONS: These results suggest that CXCL13 and CCL20 might play major roles in RA pathogenesis by acting singly on their selective receptors and synergistically in the accumulation of B cells within the inflamed synovium. …”
Publicado 2018
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10767por Saliba, Soraya Wilke, Jauch, Hannah, Gargouri, Brahim, Keil, Albrecht, Hurrle, Thomas, Volz, Nicole, Mohr, Florian, van der Stelt, Mario, Bräse, Stefan, Fiebich, Bernd L.“…BACKGROUND: Neuroinflammation plays a vital role in Alzheimer’s disease and other neurodegenerative conditions. …”
Publicado 2018
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10768“…BACKGROUND/AIMS: The dysregulation of circABCB10 may play an critical role in tumor progression. However, its function in liver cancer (HCC) is still unclear. …”
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10769por Shintani, Yusuke, Ito, Tomoya, Fields, Laura, Shiraishi, Manabu, Ichihara, Yuki, Sato, Nobuhiko, Podaru, Mihai, Kainuma, Satoshi, Tanaka, Hiroyuki, Suzuki, Ken“…Recent research has shown that reparative (alternatively activated or M2) macrophages play a role in repair of damaged tissues, including the infarcted hearts. …”
Publicado 2017
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10770“…Our findings also suggest that geographic location may play a quite limited role in structuring of larval microbiomes. …”
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10771por Pavone, Piero, Polizzi, Agata, Marino, Simona Domenica, Corsello, Giovanni, Falsaperla, Raffaele, Marino, Silvia, Ruggieri, Martino“…An increasing number of genes, proteins, and signaling pathways play crucial roles in the pathogenesis. This condition is currently regarded as a spectrum of disorders: the so-called infantile spasm syndrome (ISs), in association with other causal factors, including structural, infectious, metabolic, syndromic, and immunologic events, all acting on a genetic predisposing background. …”
Publicado 2020
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10772“…More intriguingly, HOXD8 acted as a transcription factor to activate LINC01116 in BCa. …”
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10773“…Institutions developing the app were called upon to fulfil the commitment to public trust by acting with trustworthiness. Such calls presuppose that public trust associated with the app can emerge if the conditions for trustworthiness are met and that public trust is simplistic, i.e., linearly the sum of each member of the publics’ individual – U.K. government trust relationship. …”
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10774“…The high haplotypic diversity and expected mating type ratio of 1:1 in combination with significant linkage disequilibrium suggested that a mixed reproductive strategy occurs in the B. maydis population in Fujian Province. …”
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10775por Höpfinger, Alexandra, Schmid, Andreas, Schweitzer, Leonie, Patz, Marissa, Weber, Anja, Schäffler, Andreas, Karrasch, Thomas“…CAMP, therefore, might play a role as an adipokine in metaflammation and adipose inflammation. …”
Publicado 2023
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10776por Douradinha, Bruno, Augustijn, Kevin D, Moore, Sally G, Ramesar, Jai, Mota, Maria M, Waters, Andrew P, Janse, Chris J, Thompson, Joanne“…RESULTS: Disruption of pcrmp3 and pcrmp4 in P. berghei revealed that they are also essential for transmission of the parasite through the mosquito vector, although acting in a distinct way to pbcrmp1 and 2. Mutants lacking expression of PCRMP3 or PCRMP4 show normal blood stage development and oocyst formation in the mosquito and develop into morphologically normal sporozoites, but these have a defect in egress from oocysts and do not enter the salivary glands. …”
Publicado 2011
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10777por Bilgiç, Huseyin B., Karagenç, Tülin, Simuunza, Martin, Shiels, Brian, Tait, Andy, Eren, Hasan, Weir, William“…A common feature of these diseases is that, following recovery from primary infection, animals become persistent carriers of the pathogen and continue to play a critical role in disease epidemiology, acting as reservoirs of infection. …”
Publicado 2013
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10778por Enzo, Maria Vittoria, Rastrelli, Marco, Rossi, Carlo Riccardo, Hladnik, Uros, Segat, Daniela“…In the first case germline or somatic mutations of the Wnt components are associated to several diseases such as the familial adenomatous polyposis (FAP) - caused by germline mutations of the tumor suppressor adenomatous polyposis coli gene (APC) - and the desmoid-like fibromatosis, a sporadic tumor associated with somatic mutations of the β-catenin gene (CTNNB1). In the second case, epigenetic modifications and microenvironmental factors have been demonstrated to play a key role in Wnt pathway activation. …”
Publicado 2015
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10779por Liu, Shuqing, Guo, Chunmei, Wang, Jiasheng, Wang, Bo, Qi, Houbao, Sun, Ming-Zhong“…Using a pair of syngeneic murine hepatocarcinoma cells, Hca-P with ~25% and Hca-F with ~75% lymph node metastatic (LNM) potentials, we demonstrated Anxa11 involvement in hepatocarcinoma lymphatic metastasis. Here, ANXA11 acted as a suppressor for the tumorigenicity, LNM and 5-FU resistance of Hca-P via c-Jun. …”
Publicado 2016
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10780por Herath, H. M. M. T. B., Pahalagamage, S. P., Yogendranathan, Nilukshana, Wijayabandara, M. D. M. S., Kulatunga, Aruna“…It contains triazapentadiene, which is a centrally acting alpha-2 adrenergic agonist. Amitraz poisoning is fairly uncommon in humans and occurs via oral, dermal or inhalational routes. …”
Publicado 2017
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