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10861por Bin Dajem, Saad M., Ahmed, Md Atique, Fe F Bohol, Marie, Wazid, Syeda Wasfeea, Shafeai, Mohammed I., Rudiny, Fuad H., Motaen, Ali M., Morsy, Kareem, Alothaid, Hani, Al-Qahtani, Ahmed A.“…Genealogical relationship haplotype network of PfKAHRP from 4 different countries (i.e., Saudi Arabia, Iran, Burundi, and India) revealed 1 major shared haplotype cluster (H_1) with samples representative from all 4 countries (Saudi Arabia; n = 441, Burundi; n = 4, Iran; n = 13, and India; n = 1). …”
Publicado 2022
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10862por Alzahrani, Nasser M., Paddock, Michael, Jeanes, Annmarie, Shuweihdi, Farag, Offiah, Amaka C.“…Radiologic technologists and radiologists play a vital role in the diagnosis of suspected physical child abuse. …”
Publicado 2022
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10863“…ECM proteins such as thrombospondin4, thrombospondin1, IL1RL1, and tissue inhibitors of metalloproteinase 1 play a central role and can be used as specific biomarkers determining the efficacy of LIPUS and viable clinical therapeutic targets of TMJOA.…”
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10864por Zhang, Guangde, Sun, Haoran, Zhang, Yawei, Zhao, Hengqiang, Fan, Wenjing, Li, Jianfei, Lv, Yingli, Song, Qiong, Li, Jiayao, Zhang, Mingyu, Shi, Hongbo“…Accumulating evidence has demonstrated that long non-coding RNAs (lncRNAs) acting as competing endogenous RNAs (ceRNAs) play important roles in initiation and development of human diseases. …”
Publicado 2018
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10865por Cheng, Zihan, Zhang, Xuemei, Yao, Wenjing, Gao, Yuan, Zhao, Kai, Guo, Qing, Zhou, Boru, Jiang, TingboEnlace del recurso
Publicado 2021
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10866por Roy, Sreeja, Liu, Ho-Ying, Jaeson, Muhammad Irwan, Deimel, Lachlan Paul, Ranasinghe, Charani“…This study demonstrates that 24 h following viral vector-based vaccination IL-13Rα2 functions as a master sensor on conventional dendritic cells (cDCs), abetted by high protein stability coupled with minimal mRNA expression, to rapidly regulate DC mediated IL-13 responses at the lung mucosae, unlike IL-13Rα1. Under low IL-13, IL-13Rα2 performs as a primary signalling receptor, whilst under high IL-13, acts to sequester IL-13 to maintain homeostasis, both in a STAT3-dependent manner. …”
Publicado 2020
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10867por Osmanovic, Alma, Förster, Alisa, Widjaja, Maylin, Auber, Bernd, Das, Anibh M., Christians, Anne, Brand, Frank, Petri, Susanne, Weber, Ruthild G.“…RESULTS: A rare heterozygous SUMO4 variant, i.e., SUMO4:c.2T>C p.Met1?, was detected in four of 222 (1.8%) ALS patients, significantly more frequently than in two control cohorts (0.3% each). …”
Publicado 2022
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10868“…Chemotypes distribution is linked to the population location and not to bioclimate, indicating that local selective environmental factors acted on the chemotype diversity. CONCLUSIONS: The major compounds at the species level were α-pinene (7.41-13.94%), 1,8-cineole (7.55-22.07%), cis-sabinene hydrate (0.10-12.95%), camphor (6.8-19.93%), 4-terpineol (1.55-11.86%), terpenyl acetate (0-14.92%) and viridiflorol (0-11.49%). …”
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10869“…The presence of SF3b6 influences motions of 16 residues that interact with U2 snRNA/branchpoint duplex and supports the participation of its interface residues in long-range communication in the SF3b1. These results advocate that SF3b6 potentially acts as an allosteric regulator of SF3b1 for BPS selection and might play a role in alternative splicing. …”
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10870por Chen, Jiansheng, Chen, Taoliang, Zhu, Yubo, Li, Yan, Zhang, Yuxuan, Wang, Yun, Li, Xiao, Xie, Xiaomi, Wang, Jihui, Huang, Min, Sun, Xinlin, Ke, YiquanEnlace del recurso
Publicado 2019
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10871por Saal, Marius, Loeffler-Wirth, Henry, Gruenewald, Thomas, Doxiadis, Ilias, Lehmann, Claudia“…These data indicate that the genetically determined balance between the cytokines acting on different T helper cell subsets may play a pivotal role in transmission of and susceptibility to SARS-CoV-2 infection. …”
Publicado 2023
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10872por Ryu, Jaeyoon, Jhun, Jooyeon, Park, Min-Jung, Baek, Jin-ah, Kim, Se-Young, Cho, Keun-Hyung, Choi, Jeong-Won, Park, Sung-Hwan, Choi, Jong Young, Cho, Mi-La“…Fingolimod (FTY720), an analogue of sphingosine-1-phosphate (S1P), is an effective immunosuppressive agent in experimental transplantation models. …”
Publicado 2020
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10873“…To manifest TTTY15 functions in I/R injury, Neuro 2a (N2a) cells were exposed to oxygen-glucose deprivation/reoxygenation (OGD/R) and treated with si-NC, pcDNA3.1-NC, si-TTTY15 or pcDNA3.1-TTTY15. …”
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10874por Zanella, Isabella, Focà, Emanuele, Degli-Antoni, Melania, Castelli, Francesco, Quiros-Roldan, Eugenia“…OUTCOMES: The woman had CD4(+) and CD8(+) T cell normal values and spontaneously controlled serum HIV-1 RNA levels for 30 years. LESSONS: We assume that the interplay between the HFE H63D variant in homozygosity and innate immunity, perhaps through autophagy regulation, could play a role in HIV-1 replication control in our patient. …”
Publicado 2021
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10875“…The cis element for R2R3 MYBs including Ipomoea MYB1 and Magnolia MYB1, for instance, was found to be ANCNACC, and that for bHLHs (exemplified by Ipomoea bHLH2 and petunia AN1) was CACNNG. …”
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10876“…METHODS: This study enrolled adults with schizophrenia or bipolar I disorder who initiated APT treatment at various time points: 1) within 8 weeks of initiating risperidone long-acting injectables (RLAIs) or other APTs except paliperidone palmitate (PP), 2) after more than 24 weeks of continuous RLAI treatment, or 3) at any time after initiating PP LAI treatment (schizophrenia only). …”
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10877por Wang, Junxiang, Yang, Xiaozhen, He, Huan, Chen, Jingru, Liu, Yuanyuan, Huang, Wanting, Ou, Luru, Yang, Zhaohui, Guan, Xiong, Zhang, Lingling, Wu, Songqing“…In this study, our results provide the direct molecular evidence demonstrating that two Cry-binding APN isoforms (AeAPN1 and AeAPN2) did not play a key role in mediating Bti Cry4Ba and Cry11Aa toxicity in Ae. aegypti larvae. …”
Publicado 2021
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10878por Ma, Xiao-Xiao, Qiu, Yang-Yuan, Chang, Zhi-Guang, Gao, Jun-Feng, Jiang, Rui-Ruo, Li, Chun-Lin, Wang, Chun-Ren, Chang, Qiao-Cheng“…The excretory-secretory products (ESPs) of C. sinensis play important roles in host-parasite interactions by acting as causative agents. …”
Publicado 2021
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10879“…One major effect of MAP kinase signalling is to promote gene expression through the phosphorylation and activation of transcription factors like ELK1. …”
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10880“…Hardware section includes one or several digital phone lines, a modem card with voice playing capability and a PC. …”
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