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  1. 10941
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    UBQLN4 promotes progression of HCC via activating wnt-β-catenin pathway and is regulated by miR-370
  2. 10942
    “…Nevertheless, CoVs have evolved viral proteins that target different signaling pathways to counteract innate immune responses. Some CoV proteins act as antagonists of interferon (IFN) by inhibiting IFN production or signaling, aspects that are briefly addressed in this review. …”
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    Coronavirus virulence genes with main focus on SARS-CoV envelope gene
  3. 10943
    “…The mRNA expression of IL-17RB (9.83 ± 0.35 vs 9.19 ± 0.58), TSLP (16.98 ± 2.12 vs 15.07 ± 2.25), retinoid acid receptor related orphan receptor α (7.18 ± 0.71 vs 5.46 ± 1.09) and trans-acting T-cell-specific transcription factor 3 (4.86 ± 0.66 vs 4.19 ± 0.90) were significantly increased in infants with bronchiolitis versus the control group (P < 0.05), while there was no statistical significance for suppression of tumorigenicity 2 (5.59 ± 0.68 vs 5.41 ± 0.87, P > 0.05). …”
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    The role of peripheral type 2 innate lymphoid cells in bronchiolitis
  4. 10944
    “…Inflammatory cells play an important role in the occurrence of hypertension. …”
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    Alteration of the IL-33-sST2 pathway in hypertensive patients and a mouse model
  5. 10945
    “…Dielectric/metal/dielectric plasmonic transparent structures play an important role in tailoring the high-optical performance of various optoelectronic devices. …”
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    Functional optical design of thickness-optimized transparent conductive dielectric-metal-dielectric plasmonic structure
  6. 10946
    “…Microglial activation is believed to play a role in many psychiatric and neurodegenerative diseases. …”
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    Differential Effects of Toll-Like Receptor Activation and Differential Mediation by MAP Kinases of Immune Responses in Microglial Cells
  7. 10947
    “…In the title dinuclear Cd(II) complex, [Cd(2)(C(2)N(4)O(2))(2)(C(10)H(8)N(2))(2)(H(2)O)(2)], each Cd atom is in a slightly distorted octa­hedral coordination by two N atoms and one O atom of two 1H-tetra­zole-5-carboxyl­ate (TZC) ligands, two N atoms of a 2,2′-bipyridyl ligand and one water O atom. …”
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    Bis(μ-5-carboxyl­atotetra­zolido)bis­[aqua­(2,2′-bipyrid­yl)cadmium(II)]
  8. 10948
    “…Umami taste (corresponds to savory in English) is elicited by L-glutamate, typically as its Na salt (monosodium glutamate: MSG), and is one of five basic taste qualities that plays a key role in intake of amino acids. …”
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    Genetic and Molecular Basis of Individual Differences in Human Umami Taste Perception
  9. 10949
    “…MicroRNAs (miRNAs) are small RNA molecules that regulate the expression of protein-coding genes. miRNA-mediated gene regulation plays an important role in EC. By cross-referencing studies from NCBI, we found that microRNA-375 (miR-375) is one of the most frequently downregulated miRNAs in EC. …”
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    Downregulation of miR-375 contributes to ERBB2-mediated VEGFA overexpression in esophageal cancer
  10. 10950
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    HDAC6 regulates primordial follicle activation through mTOR signaling pathway
  11. 10951
    “…Five different molecular partners for hnRNP A2 have been identified in the A2 pathway: hnRNP A2 itself, transportin, A2RE RNA, TOG (tumor overexpressed gene) and hnRNP E1, each playing a key role in one particular step of the A2 pathway. …”
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    Rules of engagement promote polarity in RNA trafficking
  12. 10952
    “…CONCLUSION: SFJD may play a role in the prevention and treatment of COVID-19 through multiple active compounds acting on multiple targets and then multiple pathways.…”
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    Analysis of the mechanism of Shufeng Jiedu capsule prevention and treatment for COVID-19 by network pharmacology tools
  13. 10953
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    MiR-690, a Runx2-targeted miRNA, regulates osteogenic differentiation of C2C12 myogenic progenitor cells by targeting NF-kappaB p65
  14. 10954
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    MiR-10a-5p targets TFAP2C to promote gemcitabine resistance in pancreatic ductal adenocarcinoma
  15. 10955
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    Invasion-related circular RNA circFNDC3B inhibits bladder cancer progression through the miR-1178-3p/G3BP2/SRC/FAK axis
  16. 10956
    “…Our findings suggest that further development of this compound and its derivatives may lead to the identification of new therapeutic antitumor agents acting through inhibition of KDM4A.…”
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    A New Family of Jumonji C Domain-Containing KDM Inhibitors Inspired by Natural Product Purpurogallin
  17. 10957
    “…Also, the stable hydrogen bonds between Ala83 (nsp16) and Tyr96 (nsp10), and between Gln87 (nsp16) and Leu45 (nsp10) play a vital role in the dimerization of nsp16 and nsp10. …”
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    Computational Investigation of Structural Dynamics of SARS-CoV-2 Methyltransferase-Stimulatory Factor Heterodimer nsp16/nsp10 Bound to the Cofactor SAM
  18. 10958
    “…Endothelial progenitor cells (EPCs) play a vital role in endothelial repair following vascular injury by maintaining the integrity of endothelium. …”
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    Cyclic Stretch Induces Vascular Smooth Muscle Cells to Secrete Connective Tissue Growth Factor and Promote Endothelial Progenitor Cell Differentiation and Angiogenesis
  19. 10959
    “…Domain of unknown function 4228 (DUF4228) proteins are a class of proteins widely found in plants, playing an important role in response to abiotic stresses. …”
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    Genome-Wide Analysis of the DUF4228 Family in Soybean and Functional Identification of GmDUF4228–70 in Response to Drought and Salt Stresses
  20. 10960
    “…Furthermore, these effects are mediated by GR acting directly to repress Cxcr2 gene expression. …”
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    Inhibition of CXCR2 by Glucocorticoids in Adipose Tissue
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