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  1. 11081
    “…Due to a high recurrence rate, frequent surveillance strategies and intravesical drug therapies, BC is considered one of the most expensive tumors to treat. As a fundamental evolutionary catabolic process, autophagy plays an important role in the maintenance of cellular environmental homeostasis by degrading and recycling damaged cytoplasmic components, including macromolecules and organelles. …”
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    Autophagy modulation in bladder cancer development and treatment
  2. 11082
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    hnRNPK-regulated LINC00263 promotes malignant phenotypes through miR-147a/CAPN2
  3. 11083
    “…BACKGROUND: Fear of pain and coping strategies are emotional-behavioral responses to pain and are known to play an important role in the development and maintenance of pain. …”
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    Influence of Fear of Pain and Coping Strategies on Health-Related Quality of Life and Patient-Anticipated Outcomes in Patients With Chronic Pain: Cross-Sectional Study Protocol
  4. 11084
    “…The altered immune response could play a critical role in the clinical presentation of these patients. …”
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    Infections and spinal cord injury: Covid-19 and beyond
  5. 11085
    por Alshammari, Thamir M.
    Publicado 2016
    “…BACKGROUND: Drug safety is one of the hottest topics in daily medical practice, particularly with regard to approving new medication or questioning the possibility of withdrawing a drug from the market. …”
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    Drug safety: The concept, inception and its importance in patients’ health
  6. 11086
    “…BACKGROUND: Circular ribonucleic acids (circRNAs) play a key role in the development of different types of cancer. …”
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    CircP4HB regulates ferroptosis via SLC7A11-mediated glutathione synthesis in lung adenocarcinoma
  7. 11087
    “…We confirmed that SMC4 may play an important role in hepatoma cell autophagy and could promote autophagy to increase the drug resistance of hepatoma cells. …”
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    SMC4 enhances the chemoresistance of hepatoma cells by promoting autophagy
  8. 11088
    “…Physical activity (HR0.6; P = 0.031) and treatment with long-acting anticholinergics (HR0.7; P = 0.044) seemed to play a significant protective role. …”
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    Predictive factors for exacerbation and re-exacerbation in chronic obstructive pulmonary disease: an extension of the Cox model to analyze data from the Swiss COPD cohort
  9. 11089
    “…Human ABCG2, a member of the ATP-binding cassette transporter superfamily, plays a key role in multidrug resistance and protecting cancer stem cells. …”
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    Dynamic vs Static ABCG2 Inhibitors to Sensitize Drug Resistant Cancer Cells
  10. 11090
    por Romano, Corrado, Schepis, Carmelo
    Publicado 2012
    “…The negative regulation of cell interactions with the extracellular matrix could be the way PTEN phosphatase acts as a tumor suppressor. PTEN gene plays an essential role in human development. …”
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    PTEN Gene: A Model for Genetic Diseases in Dermatology
  11. 11091
    por Hamidi, Mani, Emberly, Eldon
    Publicado 2013
    “…In multicellular organisms one can find examples where a growing tissue divides up until some final fixed cell number. …”
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    A Model for Cell Population Size Control Using Asymmetric Division
  12. 11092
    “…Organism body size has been demonstrated to be a discriminating element in shaping the response of living beings to environmental factors, thus playing a fundamental role in community structuring. …”
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    A Multi Size-Level Assessment of Benthic Marine Communities in a Coastal Environment: Are They Different Sides of the Same Coin?
  13. 11093
    “…This points to different mechanisms of phototropin operation in the regulation of senescence-associated processes, either with both photoreceptors acting redundantly, or only one of them, phot1, playing a dominant role.…”
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    Arabidopsis Phototropins Participate in the Regulation of Dark-Induced Leaf Senescence
  14. 11094
    “…Increasing evidence has confirmed that deubiquitinating enzymes play an important role in lung cancer progression. …”
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    OTUB2 stabilizes U2AF2 to promote the Warburg effect and tumorigenesis via the AKT/mTOR signaling pathway in non-small cell lung cancer
  15. 11095
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    Downregulation of miR-322 promotes apoptosis of GC-2 cell by targeting Ddx3x
  16. 11096
    “…The current study investigated the independent and combined effects of caffeine and taurine on anxiety-like behavior and neuroendocrine responses in adult zebrafish (Danio rerio). Caffeine (1,3,7-trimethylpurine-2,6-dione), the world’s most commonly used psychoactive drug, acts as an adenosine receptor blocker and a mild central nervous system stimulant. …”
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    Anxiety-like behavior and whole-body cortisol responses to components of energy drinks in zebrafish (Danio rerio)
  17. 11097
    “…Moreover, Argonaute 2 immunoprecipitation sequencing, qRT-PCR, and luciferase assay identified Crem, Fn1, and Stc1 are direct targets of miR-146b and elucidated that miR-146b acted as a potential regulator and promising target to understand the insulin signaling network. …”
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    Multi-omics profiling reveals microRNA-mediated insulin signaling networks
  18. 11098
    “…In fact, it is believed that nervous system development and its potential to evolve a seemingly infinite array of behavioral innovations played a major role in the successful diversification of metazoans, including our own human lineage. …”
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    Neurogenomics and the role of a large mutational target on rapid behavioral change
  19. 11099
    “…Registered on February 1, 2021.…”
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    Evaluating the efficacy of an online, family-based intervention to promote adolescent sexual health: a study protocol for a randomized controlled trial
  20. 11100
    “…Meanwhile, 3 genes including VvXBCP1, VvSAG12–1, and VvALP1 showed higher expression at 24 h after pathogen inoculation in the susceptible variety and might be related to the downy mildew phenotype. …”
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    “The PLCP gene family of grapevine (Vitis vinifera L.): characterization and differential expression in response to Plasmopara Viticola”
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