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  1. 11201
    “…Obesity is considered as a risk factor of osteoarthritis (OA), but the precise relationship is still poorly understood. Leptin, one of the most relevant factors secreted by adipose tissues, plays an important role in the pathogenesis of OA. …”
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    Leptin Induced TLR4 Expression via the JAK2-STAT3 Pathway in Obesity-Related Osteoarthritis
  2. 11202
    “…According to the previous studies, polydatin is a versatile natural compound and exerts significantly protective and curative effects on oxidative stress-associated liver diseases via various molecular mechanisms, including amelioration of liver function and insulin resistance, inhibition of proinflammatory cytokines, lipid accumulation, endoplasmic reticulum stress and autophagy, regulation of PI3K/Akt/mTOR, and activation of hepatic stellate cells (HSCs), as well as increase of antioxidant enzymes (such as catalase (CAT), glutathione peroxidase (GPx), glutathione (GSH), superoxide dismutase (SOD), glutathione reductase (GR), and heme oxygenase-1 (HO-1)). In addition, polydatin acts as a free radical scavenger against reactive oxygen species (ROS) by its phenolic and ethylenic bond structure. …”
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    Polydatin: A Critical Promising Natural Agent for Liver Protection via Antioxidative Stress
  3. 11203
    “…Surprisingly, we found no phylogenetic signal within the trait, which demonstrates that ecology (different surfaces and substrates) has acted as one of the primary selective forces in the diversification of claw shapes. …”
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    Testing for phylogenetic signal in claws suggests great influence of ecology on Caribbean intertidal arthropods (Acari, Oribatida)
  4. 11204
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    Mitophagy-related long non-coding RNA signature predicts prognosis and drug response in Ovarian Cancer
  5. 11205
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    Impaired immunosuppressive effect of bone marrow mesenchymal stem cell-derived exosomes on T cells in aplastic anemia
  6. 11206
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    Genomic patterns of divergence in the early and late steps of speciation of the deep-sea vent thermophilic worms of the genus Alvinella
  7. 11207
    “…Among these genes, more than 64.76% have more than one pA site. Our results also support that APA plays a significant role in increasing transcriptome diversity and gene expression regulation in Spodoptera frugiperda. …”
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    Analysis of Polyadenylation Signal Usage with Full-Length Transcriptome in Spodoptera frugiperda (Lepidoptera: Noctuidae)
  8. 11208
    “…DYY might play a vital role in treating COVID-19 by suppressing the inflammatory storm and regulating immune function. …”
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    Mechanism of Dayuanyin in the treatment of coronavirus disease 2019 based on network pharmacology and molecular docking
  9. 11209
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    Identifying bidirectional total and non-linear information flow in functional corticomuscular coupling during a dorsiflexion task: a pilot study
  10. 11210
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    The CaCA superfamily genes in Saccharum: comparative analysis and their functional implications in response to biotic and abiotic stress
  11. 11211
    por Shalini, Sonia, Kumar, Sharad
    Publicado 2015
    “…It acts as a tumor suppressor, prevents genetic instability, and protects against aging by playing a crucial role in sensing alterations in cellular redox status and activating the antioxidant defense system. …”
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    Caspase-2 and the oxidative stress response
  12. 11212
    “…An early surveillance checkpoint acts at the transcription site and prevents the release of mRNAs that carry processing defects. …”
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    Splice-Site Mutations Cause Rrp6-Mediated Nuclear Retention of the Unspliced RNAs and Transcriptional Down-Regulation of the Splicing-Defective Genes
  13. 11213
    “…VEGFA is one of the therapeutic targets of treatment for ocular diseases with neovascularization. …”
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    Transcriptional Regulation of VEGFA by the Endoplasmic Reticulum Stress Transducer OASIS in ARPE-19 Cells
  14. 11214
    “…Associations between DNA methylation and gene expression reveal a system-wide regulation of immune-relevant functions, likely playing a role in regulating a participant’s propensity to respond to vaccination. …”
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    System-Wide Associations between DNA-Methylation, Gene Expression, and Humoral Immune Response to Influenza Vaccination
  15. 11215
    “…Here, we isolated an APETALA2/ETHYLENE‐RESPONSIVE FACTOR (AP2/ERF) domain‐containing transcription factor (TF), NtERF172, which was strongly induced by drought, abscisic acid (ABA) and H(2)O(2), from tobacco (Nicotiana tabacum) by yeast one‐hybrid screening. NtERF172 localized to the nucleus and acted as a transcriptional activator. …”
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    The AP2 transcription factor NtERF172 confers drought resistance by modifying NtCAT
  16. 11216
    “…Cis-acting elements and protein–protein interaction networks showed that GubZIPs in one subfamily are involved in multiple functions, while some GubZIPs from different subfamilies may share the same functional category. …”
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    Genome-Wide Characterization and Expression Analysis of bZIP Gene Family Under Abiotic Stress in Glycyrrhiza uralensis
  17. 11217
    “…Reality is acting upon us, and we, and life in general, are acting upon reality. …”
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    Integral Biomathics: Tracing the Road to Reality
  18. 11218
    por Shepherd, Joshua
    Publicado 2015
    “…I then ask how experiences of trying might relate to the perceptual experiences one has while acting. …”
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    Conscious Action/Zombie Action
  19. 11219
    “…Whereas, another important glycoprotein gD without which viral entry to the cell is not possible, acts as a co-activator for the gB-gH-gL complex formation. …”
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    Computational repositioning of ethno medicine elucidated gB-gH-gL complex as novel anti herpes drug target
  20. 11220
    “…Edaphic cyanobacteria and algae have been extensively studied in dryland soils because they play key roles in the formation of biological soil crusts and the stabilization of soil surfaces. …”
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    Soil Photosynthetic Microbial Communities Mediate Aggregate Stability: Influence of Cropping Systems and Herbicide Use in an Agricultural Soil
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