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  1. 11241
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    Full high-throughput sequencing analysis of differences in expression profiles of long noncoding RNAs and their mechanisms of action in systemic lupus erythematosus
  2. 11242
    “…The shelf life of palm oil was checked by adding cinnamon extract in oil at different levels (i.e.), 0.05, 0.10, 0.15, 0.20 and 0.25%, to compare the antioxidant potential of the extract whereas, T(o) acted as control and T(BHA) @ 0.1% was used as synthetic antioxidant in the oil samples. …”
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    Antioxidant capacity of cinnamon extract for palm oil stability
  3. 11243
    “…BACKGROUND: Mitogen-activated protein kinases (MAPKs) are ubiquitous signal transduction components in eukaryotes. In plants, MAPKs play an essential role in growth and development, phytohormone regulation, and abiotic stress responses. …”
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    Genome-wide identification of the mitogen-activated kinase gene family from Limonium bicolor and functional characterization of LbMAPK2 under salt stress
  4. 11244
    por Merlo, Domenico Franco, Agramunt, Silvia, Anna, Lívia, Besselink, Harrie, Botsivali, Maria, Brady, Nigel J., Ceppi, Marcello, Chatzi, Leda, Chen, Bowang, Decordier, Ilse, Farmer, Peter B., Fleming, Sarah, Fontana, Vincenzo, Försti, Asta, Fthenou, Eleni, Gallo, Fabio, Georgiadis, Panagiotis, Gmuender, Hans, Godschalk, Roger W., Granum, Berit, Hardie, Laura J., Hemminki, Kari, Hochstenbach, Kevin, Knudsen, Lisbeth E., Kogevinas, Manolis, Kovács, Katalin, Kyrtopoulos, Soterios A., Løvik, Martinus, Nielsen, Jeanette K, Nygaard, Unni Cecilie, Pedersen, Marie, Rydberg, Per, Schoket, Bernadette, Segerbäck, Dan, Singh, Rajinder, Sunyer, Jordi, Törnqvist, Margareta, van Loveren, Henk, van Schooten, Frederik J., Vande Loock, Kim, von Stedingk, Hans, Wright, John, Kleinjans, Jos C., Kirsch-Volders, Micheline, van Delft, Joost H.M.
    Publicado 2013
    “…Background: Leukemia incidence has increased in recent decades among European children, suggesting that early-life environmental exposures play an important role in disease development. Objectives: We investigated the hypothesis that childhood susceptibility may increase as a result of in utero exposure to carcinogens and hormonally acting factors. …”
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    Micronuclei in Cord Blood Lymphocytes and Associations with Biomarkers of Exposure to Carcinogens and Hormonally Active Factors, Gene Polymorphisms, and Gene Expression: The NewGeneris Cohort
  5. 11245
    “…Bimolecular fluorescence complementation analysis demonstrated ZjBAM1-ZjAMY3, ZjBAM8-ZjDPE1, and ZjBAM7-ZjDPE1 protein interactions that were mainly present in the plasma membrane and nucleus. …”
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    Genome-wide identification of BAM (β-amylase) gene family in jujube (Ziziphus jujuba Mill.) and expression in response to abiotic stress
  6. 11246
    “…RESULTS: The 489 participating subjects had a mean age of 25, 75% were male, 44% African-American and 35% Caucasian. 46.0% had <=1 year lifetime antipsychotic exposure. As a result of the staff training at AOM sites only 14% of potential subjects declined participation because of the LAI treatment, and 91% of eligible subjects received at least one LAI treatment within the first three months of study. …”
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    O4.2. THE PREVENTION OF RELAPSE AND HOSPITALIZATION IN FIRST EPISODE AND EARLY PHASE SCHIZOPHRENIA: RESULTS FROM THE PRELAPSE TRIAL
  7. 11247
    “…Data included transcripts of the decision-making meetings and of one-on-one interviews with committee members before and after the group decision-making meetings. …”
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    Unraveling the medical residency selection game
  8. 11248
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    The Venturia inaequalis effector repertoire is dominated by expanded families with predicted structural similarity, but unrelated sequence, to avirulence proteins from other plant-pathogenic fungi
  9. 11249
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    Single cell profiling of CD45(+) spinal cord cells reveals microglial and B cell heterogeneity and crosstalk following spinal cord injury
  10. 11250
    por S, Shiju, Sriram, K.
    Publicado 2017
    “…We frame a minimal mathematical model with the assumption that per1 acts a morning oscillator and per2 acts as an evening oscillator and to support and interpret this assumption we fit the model to the experimental data of per1/per2 circadian temporal dynamics, phase response curves (PRC's), and entrainment phenomena under various light-dark conditions. …”
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    Hypothesis driven single cell dual oscillator mathematical model of circadian rhythms
  11. 11251
    “…One mechanism of endothelial dysfunction is an increase in oxidative stress, by which the bioavailability of nitric oxide is decreased. …”
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    Bilirubin and Endothelial Function
  12. 11252
    “…The punishment witnessed by patients in the household was physical (35.5%), emotional (26.5%), and verbal (18.1%). (51.6%) of the patients answered “yes’’ when they were asked whether if their caregiver acted in a way scared patients’ of getting hurt. …”
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    Childhood maltreatment and its relation with depression and anxiety among psychiatric patients in Riyadh – KSA
  13. 11253
    “…These mechanisms play a key role in the onset and progression of rheumatoid arthritis (RA). …”
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    Pharmacological characterisation of CR6086, a potent prostaglandin E(2) receptor 4 antagonist, as a new potential disease-modifying anti-rheumatic drug
  14. 11254
    “…Multiple studies have shown that long non-coding RNAs (lncRNAs) play important roles in acting as molecular sponge for competing with microRNAs (miRNAs) to regulate downstream molecules in tumor progression. …”
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    The miR155HG/miR-185/ANXA2 loop contributes to glioblastoma growth and progression
  15. 11255
    por Goodman, J I
    Publicado 1998
    “…Dose influences mechanism; and over a wide range of doses, one can envision that mechanism will change with changing dose. …”
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    The traditional toxicologic paradigm is correct: dose influences mechanism.
  16. 11256
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    Glutaminase isoforms expression switches microRNA levels and oxidative status in glioblastoma cells
  17. 11257
    por Tsofa, B, Molyneux, S, Malingi, T, Barasa, E
    Publicado 2017
    “…METHODS: We set-up a health systems governance learning site in one of the 47 Kenyan counties, Kilifi, to analyse the implications of devolution on the health sector. …”
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    012 PP: ‘THE OUTSIDERS FROM WITHIN’ – COPING AND ADAPTIVE STRATEGIES FOR SYSTEMS RESILIENCE IN THE PROCESS OF IMPLEMENTING POLITICAL DEVOLUTION WITHIN THE HEALTH SECTOR IN KENYA
  18. 11258
    “…This multitasking protein is involved in regulating different networks of cell signaling. On one hand it shows an increased expression profile in different cancers, has a positive role in cell proliferation and migration, whereas on the other hand it promotes apoptosis under oxidative stress conditions by acting as a sensor of ROS (Reactive Oxygen Species). …”
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    p66Shc as a switch in bringing about contrasting responses in cell growth: implications on cell proliferation and apoptosis
  19. 11259
    “…This may indicate that playing a critical role in society during an episode of crisis, and acting to help others, may be protective of one’s own mental health. …”
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    Psychological distress and resilience in first responders and health care workers during the COVID‐19 pandemic
  20. 11260
    “…Leishmania are intracellular protozoan parasites that cause a wide spectrum of clinical manifestations in genetically susceptible individuals with an insufficient or balanced Th1 immune response to eliminate the parasite. MiRNAs play important regulatory role in numerous biological processes including essential cellular functions. miR146-a acts as an inhibitor of interleukin 1 receptor associated kinase 1 (IRAK1) and tumour necrosis factor (TNF) receptor associated factor 6 (TRAF6) present in the toll-like receptors pathway while miR499a modulates TGF-β and TNF signalling pathways. …”
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    Variants of MIRNA146A rs2910164 and MIRNA499 rs3746444 are associated with the development of cutaneous leishmaniasis caused by Leishmania guyanensis and with plasma chemokine IL-8
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