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11481por Basolo, Alessio, Bechi Genzano, Susanna, Piaggi, Paolo, Krakoff, Jonathan, Santini, Ferruccio“…The interplay between energy demand and caloric intake appears designed to guarantee an adequate food supply in variable life contexts. The circadian rhythm plays a major role in systemic homeostasis by acting as “timekeeper” of the human body, under the control of central and peripheral clocks that regulate many physiological functions such as sleep, hunger and body temperature. …”
Publicado 2021
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11482“…Communication about previous acts and passing on reputational information could be valuable for conditional action in cooperation problems and pose a punishment threat to defectors. …”
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11483por D’Alessandro, Claudia, Benedetti, Alessia, Di Paolo, Antonello, Giannese, Domenico, Cupisti, Adamasco“…Drugs and food interact mutually: drugs may affect the nutritional status of the body, acting on senses, appetite, resting energy expenditure, and food intake; conversely, food or one of its components may affect bioavailability and half-life, circulating plasma concentrations of drugs resulting in an increased risk of toxicity and its adverse effects, or therapeutic failure. …”
Publicado 2022
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11484por Liu, Zhikun, Yin, Yanhong, Yang, Daijun, Zhang, Cunman, Ming, Pingwen, Li, Bing, Yang, Shuting“…Chromium hexacarbonyl plays a significant role in making Pt and Co form an alloyed NW, which acts as both a reducing agent and a structure directing agent. …”
Publicado 2020
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11485por Sun, Xingming, Zhang, Zhanying, Li, Jinjie, Zhang, Hongliang, Peng, Youliang, Li, Zichao“…In the cascading regulation among MBW members, S1 (bHLH) acts as the master gene by activating the expression of C1 (MYB), and then C1 activates the expression of WA1 (WD40), which is unique in plant species. …”
Publicado 2022
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11486“…A phylogenetic tree of CnCHSs indicated divergence into three major groups, including I, II, and III. Analyses of the genes and promoters of these genes indicated that there are many cis-acting elements that respond to light, phytohormones, stress, and developmental stages. …”
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11487“…First, the essential condition for D RNA formation is prolonged passaging of the virus at a high cellular multiplicity of infection (MOI) in one host. Second, recombination plays crucial roles in D RNA formation. …”
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11488por Mollo, Nunzia, Scognamiglio, Roberta, Conti, Anna, Paladino, Simona, Nitsch, Lucio, Izzo, Antonella“…It is likely that the contribution of more than one gene is required, and that the overexpression of Hsa21 genes acts in combination with other genetic events, such as specific mutations or polymorphisms, amplifying their effect. …”
Publicado 2023
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11489por Tanaka, Hiromitsu, Matsushita, Hiroaki, Tokuhiro, Keizo, Fukunari, Atsushi, Ando, Yukio“…SIMPLE SUMMARY: HASPIN plays important roles in chromosome segregation during cell division by phosphorylating histone H3 at threonine. …”
Publicado 2023
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11490por Wu, H. Helena, Leng, Sarah, Abuetabh, Yasser, Sergi, Consolato, Eisenstat, David D., Leng, Roger“…The tumor suppressor p53 plays a critical role in cancer pathogenesis, and regulation of p53 expression is essential for maintaining normal cell growth. …”
Publicado 2023
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11491por Zhu, Huayu, Han, Xiaoyong, Lv, Junhong, Zhao, Liang, Xu, Xiaoyang, Zhang, Tianzhen, Guo, Wangzhen“…Chromosomal location showed that 22 duplicate genes were located in which at least one fiber quality QTL was detected. The molecular evolutionary rates suggested that the D-subgenome of the allotetraploid underwent rapid evolutionary differentiation, and selection had acted at the tetraploid level. …”
Publicado 2011
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11492“…Cognitive scientists have long been interested in the role that eye gaze plays in social interactions. Previous research suggests that gaze acts as a signaling mechanism and can be used to control turn-taking behaviour. …”
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11493“…Alternative splicing is one of the most common mechanisms of human gene regulation and plays a crucial role in increasing the diversity of functional proteins. …”
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11494Expression and Regulation of pde6h by Thyroid Hormone During Metamorphosis in Paralichthys olivaceus“…PDE6H is a cone cell-specific inhibitory subunit that plays a critical role in the adaptation of the photosensitive system to bright and dark phases of the light environment. …”
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11495por Nesterova, Tatyana B., Wei, Guifeng, Coker, Heather, Pintacuda, Greta, Bowness, Joseph S., Zhang, Tianyi, Almeida, Mafalda, Bloechl, Bianca, Moindrot, Benoit, Carter, Emma J., Alvarez Rodrigo, Ines, Pan, Qi, Bi, Ying, Song, Chun-Xiao, Brockdorff, Neil“…Xist RNA, the master regulator of X chromosome inactivation, acts in cis to induce chromosome-wide silencing. …”
Publicado 2019
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11496por Gibson, Douglas A, Esnal-Zufiaurre, Arantza, Bajo-Santos, Cristina, Collins, Frances, Critchley, Hilary O D, Saunders, Philippa T K“…WHAT IS KNOWN ALREADY: Oestrogens acting via their cognate receptors are essential regulators of endometrial function and play key roles in establishment of pregnancy. …”
Publicado 2020
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11497“…However, COPI was initially characterized as an anterograde-acting coat complex. To investigate the direct and primary role(s) of COPI in ER/Golgi transport and in the secretory pathway in general, we used PCR-based mutagenesis to generate new temperature-conditional mutant alleles of one COPI gene in Saccharomyces cerevisiae, SEC21 (γ-COP). …”
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11498por Romanyuk, Andrey V., Grozdova, Irina D., Ezhov, Alexander A., Melik-Nubarov, Nickolay S.“…We designed dispersions containing polyoxalate and tetramethylhematoporhyrin (TMHP) in dimethylphthalate droplets stabilized with Pluronic L64. The porphyrin plays the dual role. On the one hand, it serves as an activator of the peroxyoxalate reaction of polyoxalate with intracellular hydrogen peroxide and experiences excitation as a result of the reaction. …”
Publicado 2017
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11499por Inoue, Tsuyoshi“…The autonomic nervous system plays an important role in maintaining homeostasis in organisms. …”
Publicado 2021
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11500“…Low risk score indicated a lower immune escape score, TIDE score, and higher PD1&CTLA4 immunophenoscore in ovarian cancer. Moreover, PRS-based risk score acted as an indicator for drug sensitivity in the immunotherapy and chemotherapy of ovarian cancer patients. …”
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