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  1. 11501
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    Molecular Analysis of a Leprosy Immunotherapeutic Bacillus Provides Insights into Mycobacterium Evolution
  2. 11502
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    A PXR-Mediated Negative Feedback Loop Attenuates the Expression of CYP3A in Response to the PXR Agonist Pregnenalone-16α-Carbonitrile
  3. 11503
    “…Previous studies suggest a differential role for p38 mitogen-activated kinase (MAPK) during wound healing; whereby, p38 MAPK acts as a growth kinase during normal wound healing, but acts as a stress kinase during diabetic wound repair. …”
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    Modification of Collagen by 3-Deoxyglucosone Alters Wound Healing through Differential Regulation of p38 MAP Kinase
  4. 11504
    “…We show that Hoxb1 acts as an activator to establish the full expression domain of CRABPI and II in rhombomere 4 and as a repressor to restrict expression of Lhx5 and Lhx9. …”
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    Directed Neural Differentiation of Mouse Embryonic Stem Cells Is a Sensitive System for the Identification of Novel Hox Gene Effectors
  5. 11505
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    Aldehyde Dehydrogenase Gene Superfamily in Populus: Organization and Expression Divergence between Paralogous Gene Pairs
  6. 11506
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    Molecular cloning, in-silico characterization and functional validation of monodehydroascorbate reductase gene in Eleusine coracana
  7. 11507
    “…Candida albicans is one of the most common fungal pathogens. Our previous study demonstrated that concomitant use of berberine (BBR) and fluconazole (FLC) showed a synergistic action against FLC-resistant C. albicans in vitro and BBR had a major antifungal effect in the synergism, while FLC played a role of increasing the intracellular BBR concentration. …”
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    Requirement for Ergosterol in Berberine Tolerance Underlies Synergism of Fluconazole and Berberine against Fluconazole-Resistant Candida albicans Isolates
  8. 11508
    “…Results: Long acting reversible contraception (LARC) was more commonly initiated through outreach strategies than through fixed sites. …”
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    To be continued: family planning continuation among the urban poor in Senegal, a prospective, longitudinal descriptive study.
  9. 11509
    “…The protein titin plays a key role in vertebrate muscle where it acts like a giant molecular spring. …”
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    Evolution of the Highly Repetitive PEVK Region of Titin Across Mammals
  10. 11510
    por Million, Kara M., Lively, Curtis M.
    Publicado 2022
    “…Major Histocompatibility Complex (MHC) genes are one of the most polymorphic gene groups known in vertebrates. …”
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    Trans‐specific polymorphism and the convergent evolution of supertypes in major histocompatibility complex class II genes in darters (Etheostoma)
  11. 11511
    por Zeng, Zhen, Lyu, Tong, Lyu, Yingmin
    Publicado 2022
    “…Furthermore, a yeast one hybrid (Y1H) assay proved that the AREB/ABF (ABRE-binding protein/ABRE-binding factor) from lilies (LoABF2) could bind to the promoter of LoSWEET14. …”
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    LoSWEET14, a Sugar Transporter in Lily, Is Regulated by Transcription Factor LoABF2 to Participate in the ABA Signaling Pathway and Enhance Tolerance to Multiple Abiotic Stresses in Tobacco
  12. 11512
    “…BACKGROUND: Macroevolutionary modeling of species diversification plays important roles in inferring large-scale biodiversity patterns. …”
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    Microevolutionary processes impact macroevolutionary patterns
  13. 11513
    “…BACKGROUND: Alternative splicing (AS) is one of the critical post-transcriptional regulatory mechanisms of various cancers and also plays a crucial role in the development of cancers, including endometrial cancer (EC). …”
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    Comprehensive Analysis of Prognostic Alternative Splicing Signatures in Endometrial Cancer
  14. 11514
    “…Recent studies have added a number of new proteins during cNHEJ. One of the newly identified proteins is Paralogue of XRCC4 and XLF (PAXX), which acts as a scaffold that is required to stabilize the KU70/80 heterodimer at DSBs sites and promotes the assembly and/or stability of the cNHEJ machinery. …”
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    Role of Paralogue of XRCC4 and XLF in DNA Damage Repair and Cancer Development
  15. 11515
    “…Chlorophyll (Chl) plays a crucial role in plant photosynthesis. The geranylgeraniol reductase gene (CHLP) participates in the terminal hydrogenation of chlorophyll biosynthesis. …”
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    Genome-Wide Investigation of the PtrCHLP Family Reveals That PtrCHLP3 Actively Mediates Poplar Growth and Development by Regulating Photosynthesis
  16. 11516
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    Regulation of MntH by a Dual Mn(II)- and Fe(II)-Dependent Transcriptional Repressor (DR2539) in Deinococcus radiodurans
  17. 11517
    “…Most importantly, these epigenetic lesions occur in a context of piRNA downregulation and loss of DNA methylation of the LINE-1 repetitive sequences, one of the target genomic loci where the PIWI/piRNA machinery acts as a caretaker in non-transformed cells.…”
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    Epigenetic loss of the PIWI/piRNA machinery in human testicular tumorigenesis
  18. 11518
    “…As a consequence, this channel acts like a “ghost” of the limit cycle destroyed in the critical transition and instead of the expected abrupt transition we find a smooth one. …”
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    Trapping Phenomenon Attenuates the Consequences of Tipping Points for Limit Cycles
  19. 11519
    “…In addition, we identified that Wnt1 was a direct target of miR-139-5p, and XIST played the oncogenic role in bladder cancer by activating the Wnt/β-catenin signaling pathway. …”
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    Long non-coding RNA XIST promotes cell growth and metastasis through regulating miR-139-5p mediated Wnt/β-catenin signaling pathway in bladder cancer
  20. 11520
    “…Herein, we show that 4-[(4-(dimethylamino)butoxy)imino]-1-methyl-1H-benzo[f]indol-9(4H)-one (CYR5099) acts as a NOX2 inhibitor and exerts a protective effect against complete Freund's adjuvant (CFA)-induced inflammatory arthritis in mice. …”
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    A novel NOX2 inhibitor attenuates human neutrophil oxidative stress and ameliorates inflammatory arthritis in mice
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