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  1. 1161
    “…In conclusion, this finding indicates that circCSPP1 may act as a promising therapeutic target by regulating the EMT process in colorectal carcinoma via activation of the circCSPP1/miR-193a-5p/COL1A1 axis.…”
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    CircCSPP1 Functions as a ceRNA to Promote Colorectal Carcinoma Cell EMT and Liver Metastasis by Upregulating COL1A1
  2. 1162
    “…We describe a Pap1–Oxs1 pathway for diamide-induced disulfide stress in Schizosaccharomyces pombe, where the nucleocytoplasmic HMG protein Oxs1 acts cooperatively with Pap1 to regulate transcription. …”
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    A Pap1–Oxs1 signaling pathway for disulfide stress in Schizosaccharomyces pombe
  3. 1163
    “…ALDH1A1 plays important roles in various diseases, especially in cancers. …”
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    ALDH1A1 in Cancers: Bidirectional Function, Drug Resistance, and Regulatory Mechanism
  4. 1164
    “…Nitric oxide (NO) can induce acute pain in humans and plays an important role in pain sensitization caused by inflammation and injury in animal models. …”
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    TRPV1 and TRPA1 Mediate Peripheral Nitric Oxide-Induced Nociception in Mice
  5. 1165
    “…CONCLUSION: Our results suggest that DJ-1 acts as a molecular chaperone to inhibit MAP1B aggregation thus leading to neuronal apoptosis. …”
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    DJ-1 can inhibit microtubule associated protein 1 B formed aggregates
  6. 1166
    por Chiba, Kenji, Adachi, Kunitomo
    Publicado 2012
    “…S1P receptor 1 (S1P(1)) plays an essential role in lymphocyte egress from secondary lymphoid organs (SLO), as evinced by the inability of lymphocytes to exit from the SLO in mice lacking lymphocytic S1P(1). …”
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    Sphingosine 1-Phosphate Receptor 1 as a Useful Target for Treatment of Multiple Sclerosis
  7. 1167
    “…Despite the roles of ESCRT‐I and ‐III in HIV budding being firmly established, participation of ESCRT‐II in this process has been controversial. …”
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    ESCRT‐II functions by linking to ESCRT‐I in human immunodeficiency virus‐1 budding
  8. 1168
    “…We conclude that SELENBP1 in adipocytes (1) contributes to H(2)S biosynthesis and (2) acts as an endogenous stimulator of adipocyte differentiation.…”
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    Selenium-Binding Protein 1 (SELENBP1) Supports Hydrogen Sulfide Biosynthesis and Adipogenesis
  9. 1169
    “…BACKGROUND: PINCH1, an adaptor protein containing five LIM domains, plays an important role in regulating the integrin-mediated cell adhesion, migration and epithelial-mesenchymal transition. …”
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    PINCH1 Is Transcriptional Regulator in Podocytes That Interacts with WT1 and Represses Podocalyxin Expression
  10. 1170
    “…Coordinated transcriptional regulation of stress-responsive genes orchestrated by a complex network of transcription factors (TFs) and the reprogramming of metabolism ensure a plant’s continued growth and survival under adverse environmental conditions (e.g., abiotic stress). DNA-binding with one finger (Dof) proteins, a group of plant-specific TF, were identified as one of several key components of the transcriptional regulatory network involved in abiotic stress responses. …”
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    Emerging Roles of Plant DNA-Binding With One Finger Transcription Factors in Various Hormone and Stress Signaling Pathways
  11. 1171
    “…Mechanistically, Pak1 phosphorylates the Mid1 N-terminus to promote its association with cortical nodes that act as CAR precursors. …”
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    Fission yeast Pak1 phosphorylates anillin-like Mid1 for spatial control of cytokinesis
  12. 1172
    “…CONCLUSION: These results suggest that OSBP1 could play a role in linking cholesterol metabolism with intracellular APP trafficking and Aβ production, and more importantly indicate that OSBP1 could provide an alternative target for Aβ-directed therapeutic.…”
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    Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein
  13. 1173
    por Wang, Yan, Wang, Ke, Fu, Jian
    Publicado 2020
    “…We also investigated the role of HDAC6 in poly (I:C)-induced anti-viral signaling such as TBK1, GSK-3β, and Akt activation in mouse BMDMs. …”
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    HDAC6 Mediates Poly (I:C)-Induced TBK1 and Akt Phosphorylation in Macrophages
  14. 1174
    “…Signal transducer and activator of transcription-1 (STAT1) plays a role in the transduction of stress and cytokine responses, DNA damage, and activation of B and T cell immune responses. …”
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    Role of STAT1 in the breast
  15. 1175
    por Journo, Chloé, Mahieux, Renaud
    Publicado 2011
    “…Herein, we will review the interplay between HTLV-1 and innate immunity. Particular emphasis is put on HTLV-1-induced alteration of type-I interferon (IFN-I) function. …”
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    HTLV-1 and Innate Immunity
  16. 1176
    “…Subnitrides (Ba(3)N, LiBa(3)N, NaBa(3)N, and Na(5)Ba(3)N) containing one-dimensional (1D) [Ba(3)N](3+) chains are identified as 3D electrides for the first time. …”
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    First-Principles Study of Three-Dimensional Electrides Containing One-Dimensional [Ba(3)N](3+) Chains
  17. 1177
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    Primary health care as a platform for addressing racial discrimination to “leave no one behind” and reduce health inequities
  18. 1178
    “…In this study, we aimed to unravel how FLI-1 and the LDB1 complex act together in murine erythroleukemia cells and in megakaryocyte. …”
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    Interplay between FLI-1 and the LDB1 complex in murine erythroleukemia cells and during megakaryopoiesis
  19. 1179
    “…CONCLUSIONS/SIGNIFICANCE: Antibodies that compete with Notch1 ligand binding or that bind to the negative regulatory region can act as potent inhibitors of Notch1 signaling. …”
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    Characterization of Notch1 Antibodies That Inhibit Signaling of Both Normal and Mutated Notch1 Receptors
  20. 1180
    “…BACKGROUND: The long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) has been reported to play a vital role in the occurrence and development of various tumors. …”
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    MALAT1/ mir-1-3p mediated BRF2 expression promotes HCC progression via inhibiting the LKB1/AMPK signaling pathway
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