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  1. 11921
    “…Background: The gut plays an important role in the development of sepsis and acts as one of the possible drivers of multiple-organ dysfunction syndrome. …”
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    GLOBAL SIGNATURES OF THE MICROBIOME AND METABOLOME DURING HOSPITALIZATION OF SEPTIC PATIENTS
  2. 11922
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    Polypyrimidine Tract Binding Protein Functions as a Negative Regulator of Feline Calicivirus Translation
  3. 11923
    “…In the Pachydactylus group, one possible explanation is a history of diversification via geographic isolation. …”
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    The measure of success: geographic isolation promotes diversification in Pachydactylus geckos
  4. 11924
    “…CONCLUSIONS: IGFBP7 expression is decreased or even absent in FTC and ATC. Acting as a cell cycle repressor, IGFBP7 plays an important tumor-suppressive role in human thyroid cancer, especially in FTC and ATC subtypes and may represent a promising biomarker and therapeutic target for human thyroid cancer treatment. …”
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    IGFBP7 inhibits cell proliferation by suppressing AKT activity and cell cycle progression in thyroid carcinoma
  5. 11925
    “…Rich) Hochst (Anacardiaceae) fraction played vital roles. The goals of the study were to determine the contents of some useful medicinal plants and the bioassay-guided fractionation substances of S. birrea fraction compounds capable of acting against Salmonella isolate using LC-MS/LC-HRMS (Dionex ultimate 3000 RS UPLC with Thermo Scientific Q Exactive Orbitrap Hybrid Tandem Mass Spectrometer). …”
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    Determination of Phenolics and Flavonoids of Some Useful Medicinal Plants and Bioassay-Guided Fractionation Substances of Sclerocarya birrea (A. Rich) Hochst Stem (Bark) Extract and Their Efficacy Against Salmonella typhi
  6. 11926
    “…[Image: see text] Background: cerebral ischemia/reperfusion (I/R) injury is an important complication of ischemic stroke, and autophagy is one of the mechanisms of it. …”
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    Role of Autophagy Mediated by AMPK/DDiT4/mTOR Axis in HT22 Cells Under Oxygen and Glucose Deprivation/Reoxygenation
  7. 11927
    “…The ratio of the non-synonymous (Ka) to synonymous (Ks) nucleotide substitution rate, denoted as ω, is an indicator of the selection pressure acting on protein-coding genes. A higher proportion of non-synonymous to synonymous substitutions (Ka/Ks or ω > 1) indicates positive selection, while Ka/Ks or ω near zero indicates purifying selection. …”
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    Natural selection shapes the evolution of SARS-CoV-2 Omicron in Bangladesh
  8. 11928
    “…The MeRKD5 and MeNLP6 proteins were localized to the cell nucleus in tobacco leaf. Five and one candidate proteins interacting with MeRKD5 and MeNLP6, respectively, were screened from the cassava nitrogen starvation library, including agamous-like mads-box protein AGL14, metallothionein 2, Zine finger FYVE domain containing protein, glyceraldehyde-3-phosphate dehydrogenase, E3 Ubiquitin-protein ligase HUWE1, and PPR repeat family protein. …”
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    Genome-Wide Survey of the RWP-RK Gene Family in Cassava (Manihot esculenta Crantz) and Functional Analysis
  9. 11929
    por Park, Si-Hyun, Kim, Jae Geun
    Publicado 2023
    “…Insects are vital pollinators for angiosperms, playing a crucial role in their reproductive success and fruit production. …”
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    Mechanistic understanding of perianth traits hindering pollination in Aristolochia contorta Bunge
  10. 11930
    Publicado 1994
    “…The CD28 receptor on T cells with its ligand B7 represents one of the best characterized and most important examples of this costimulation. …”
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    Interleukin 12 synergizes with B7/CD28 interaction in inducing efficient proliferation and cytokine production of human T cells
  11. 11931
    “…BACKGROUND: The process of cellular differentiation is governed by complex dynamical biomolecular networks consisting of a multitude of genes and their products acting in concert to determine a particular cell fate. …”
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    Using cell fate attractors to uncover transcriptional regulation of HL60 neutrophil differentiation
  12. 11932
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    Breaking the News or Fueling the Epidemic? Temporal Association between News Media Report Volume and Opioid-Related Mortality
  13. 11933
    “…BACKGROUND: Lysosomal α-mannosidase is an enzyme that acts to degrade N-linked oligosaccharides and hence plays an important role in mannose metabolism in humans and other mammalian species, especially livestock. …”
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    A multi-species comparative structural bioinformatics analysis of inherited mutations in α-D-Mannosidase reveals strong genotype-phenotype correlation
  14. 11934
    “…Such constructs may have multiple applications such as allowing for more aggressive insulin treatment regimens, treating hypoglycemia due to insulin-secreting tumors, providing synergistic efficacy in combination therapies with long-acting GLP1 analogs, and as an appetite suppressant for treatment of obesity. …”
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    Gcg-XTEN: An Improved Glucagon Capable of Preventing Hypoglycemia without Increasing Baseline Blood Glucose
  15. 11935
    “…It is also well known that Pax8, TTF-1, Foxe1 and Hhex are the thyroid-enriched transcription factors responsible for the expression of the above genes, thus are responsible for the differentiated thyroid phenotype. …”
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    Comparative genomics reveals a functional thyroid-specific element in the far upstream region of the PAX8 gene
  16. 11936
    “…Most injuries had been present for less than one week (84%), with 53% occurring through a contact mechanism. …”
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    Sports chiropractic management at the World Ice Hockey Championships
  17. 11937
    “…Upstream of FOXO3, genistein acts via the PI3K/Akt pathway to inhibit EGF-stimulated FOXO3 phosphorylation (i.e. favors active state). …”
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    Genistein inhibits proliferation of colon cancer cells by attenuating a negative effect of epidermal growth factor on tumor suppressor FOXO3 activity
  18. 11938
    “…CONCLUSIONS: It was apparent that the 'blocking effect' of xylan was one of the major mechanisms that limited the accessibility of the cellulase enzymes to the cellulose. …”
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    The enhancement of enzymatic hydrolysis of lignocellulosic substrates by the addition of accessory enzymes such as xylanase: is it an additive or synergistic effect?
  19. 11939
    “…MicroRNAs (miRNAs) are a class of noncoding RNA acting at a post-transcriptional level to control the expression of large sets of target mRNAs. …”
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    Increased Circulating miR-21 Levels Are Associated with Kidney Fibrosis
  20. 11940
    “…The ubiquitin-proteasome system plays a central role in cellular regulation and protein quality control (PQC). …”
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    Functional Diversity and Structural Disorder in the Human Ubiquitination Pathway
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