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  1. 12301
    “…We also show that similar codons in the gene of the rhodopsin RH1, a light-sensitive receptor protein, are under positive selection at the intra and interspecific scales, suggesting that similar selective pressures are acting at both levels.…”
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    Clownfishes evolution below and above the species level
  2. 12302
    por Li, Kun, Wang, Ziqiang
    Publicado 2021
    “…Increasing evidence has confirmed that SRSF2 plays vital roles in a number of biological and pathological processes. …”
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    Splicing factor SRSF2-centric gene regulation
  3. 12303
    “…Furthermore, ERF1 acts in a positive feedback loop and regulates autophagy activity by transcriptionally activating ATG expression in response to RKN infection. …”
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    Autophagy promotes jasmonate-mediated defense against nematodes
  4. 12304
    “…P. aeruginosa is present at low proportions in the community and yet, it plays a critical role in community function, suggesting it acts as a keystone species in this community. …”
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    N-Acyl Homoserine Lactone-Mediated Quorum Sensing Regulates Species Interactions in Multispecies Biofilm Communities
  5. 12305
    “…Our data indicate that HDGF acts as a coactivator of SREBP1‐mediated transcription of lipogenic genes. …”
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    Role of hepatoma‐derived growth factor in promoting de novo lipogenesis and tumorigenesis in hepatocellular carcinoma
  6. 12306
    “…BACKGROUND: Nodal signalling is an absolute requirement for normal mesoderm and endoderm formation in vertebrate embryos, yet the transcriptional networks acting directly downstream of Nodal and the extent to which they are conserved is largely unexplored, particularly in vivo. …”
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    Global identification of Smad2 and Eomesodermin targets in zebrafish identifies a conserved transcriptional network in mesendoderm and a novel role for Eomesodermin in repression of ectodermal gene expression
  7. 12307
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    Tripeptides as Integrin-Linked Kinase Modulating Agents Based on a Protein–Protein Interaction with α-Parvin
  8. 12308
    “…We found that P(i) causes cells to accumulate in G1 phase in a time-dependent manner. …”
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    Inorganic Phosphate as a Novel Signaling Molecule with Antiproliferative Action in MDA-MB-231 Breast Cancer Cells
  9. 12309
    por Magni, Giulia, Ceruti, Stefania
    Publicado 2020
    “…The molecular components of the purinergic system (i.e., receptors, metabolizing enzymes and membrane transporters) are widely expressed in the cells of the immune system. …”
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    Adenosine Signaling in Autoimmune Disorders
  10. 12310
    “…This inhibitory effect of MTII on activated microglia was blocked by siRNA-mediated downregulation of LRP1 receptor expression in microglia, suggesting that MTII acts via the LRP1 receptor on microglia. …”
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    The impact of metallothionein-II on microglial response to tumor necrosis factor-alpha (TNFα) and downstream effects on neuronal regeneration
  11. 12311
    “…Fast Inactivation in voltage-gated Na(+) channels plays essential roles in numerous physiological functions. …”
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    A Mechanistic Reinterpretation of Fast Inactivation in Voltage-Gated Na(+) Channels
  12. 12312
    “…Treatment of pre-diabetic adult NOD mice with the Hpse inhibitor PI-88 significantly reduced the incidence of T1D by ~50% and preserved islet HS. Hpse therefore acts as a novel immune effector mechanism in T1D. …”
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    Heparanase and Autoimmune Diabetes
  13. 12313
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    Bacterial cell sensing and signaling pathway for external polycyclic aromatic hydrocarbons (PAHs)
  14. 12314
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    TXNDC12 inhibits lipid peroxidation and ferroptosis
  15. 12315
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    Day and Night GSH and MDA Levels in Healthy Adults and Effects of Different Doses of Melatonin on These Parameters
  16. 12316
    por Burke, Brian
    Publicado 2019
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    Chain reaction: LINC complexes and nuclear positioning
  17. 12317
    por Rose-John, Stefan
    Publicado 2020
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    Interleukin-6 signalling in health and disease
  18. 12318
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    Selective and efficient catalytic and photocatalytic oxidation of diphenyl sulphide to sulfoxide and sulfone: the role of hydrogen peroxide and TiO(2) polymorph
  19. 12319
    “…RESULTS: We found that several of the chemicals acted as competitive inhibitors of SULT 2A1 (K(i) for 4-tert-octylphenol is 2.8 μM). …”
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    Effects of Endocrine Disruptors on Dehydroepiandrosterone Sulfotransferase and Enzymes Involved in PAPS Synthesis: Genomic and Nongenomic Pathways
  20. 12320
    “…GPBAR1, FXR, and RORγt are highly expressed in cells of the innate and adaptive immune system (i.e., dendritic cells (DCs), macrophages, innate lymphoid 3 cells (ILC3s), and T helper 17 (Th17) lymphocytes) and plays an important role in regulating intestinal and liver immunity, highlighting a role for various bile acid species in regulating immune responses to intestinal microbial antigens. …”
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    Bile Acids Activated Receptors in Inflammatory Bowel Disease
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