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  1. 12321
    por Kanat, Ozkan, Ertas, Hulya
    Publicado 2018
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    Shattering the castle walls: Anti-stromal therapy for pancreatic cancer
  2. 12322
    “…Syk acts upstream of PLCγ2 in the Dectin-1 signaling pathway. …”
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    Phospholipase Cγ2 is critical for Ca(2+) flux and cytokine production in anti-fungal innate immunity of human corneal epithelial cells
  3. 12323
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    Genome-wide expression analysis of carboxylesterase (CXE) gene family implies GBCXE49 functional responding to alkaline stress in cotton
  4. 12324
    “…In 3 of the 4 rucks in which injury occurred (75%), the concussed player was acting defensively either in the capacity of ‘support’ (n=2) or as the ‘jackal’ (n=1). …”
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    Video analysis of concussion injury mechanism in under-18 rugby
  5. 12325
    “…Myc plays critical roles in the self-renewal division of various stem cell types. …”
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    Myc/Mycn-mediated glycolysis enhances mouse spermatogonial stem cell self-renewal
  6. 12326
    “…Investigation of the mechanism of action showed that 3i presents a drug response by targeting the apicoplast and a quick-killing mechanism acting on another target site.…”
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    2-Phenoxy-3-Trichloromethylquinoxalines Are Antiplasmodial Derivatives with Activity against the Apicoplast of Plasmodium falciparum
  7. 12327
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    Distinct role of autophagy on angiogenesis: highlights on the effect of autophagy in endothelial lineage and progenitor cells
  8. 12328
    “…However, the identity of factors acting upstream in this process is less clear. Here, we examined how the canonical release factors Sup45–Sup35 (eRF1–eRF3) and their paralogs Dom34-Hbs1 affect the total population of ubiquitinated nascent chains associated with yeast ribosomes. …”
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    Distinct types of translation termination generate substrates for ribosome-associated quality control
  9. 12329
    “…IL-33 belongs to the IL-1 cytokine family and acts as binding attachments for the suppressor of tumorigenicity (ST)2 receptor. …”
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    Paradoxical role of interleukin-33/suppressor of tumorigenicity 2 in colorectal carcinogenesis: Progress and therapeutic potential
  10. 12330
    “…The EphA2-Dvl2/Axin1 interaction was enhanced by Wnt3a treatment, suggesting that EphA2 acts as a functional receptor for the Wnt/β-catenin pathway and plays a vital role in downstream signaling. …”
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    EPH receptor A2 governs a feedback loop that activates Wnt/β-catenin signaling in gastric cancer
  11. 12331
    “…BACKGROUND: Chemokine (C-C motif) receptor 6 (CCR6) is present in sperm and plays a significant role in sperm motility and chemotaxis acting in the reproductive tracts. …”
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    In vitro chemokine (C-C motif) receptor 6-dependent non-inflammatory chemotaxis during spermatogenesis
  12. 12332
    “…BACKGROUND: Tumor protein D52 (TPD52) reportedly plays an important role in the proliferation and metastasis of various cancer cells, including oral squamous cell carcinoma (OSCC) cells, and is expressed strongly at the center of the tumor, where the microenvironment is hypoxic. …”
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    Tumor protein D52 is upregulated in oral squamous carcinoma cells under hypoxia in a hypoxia-inducible-factor-independent manner and is involved in cell death resistance
  13. 12333
    “…Therefore, this review aims to provide an overview of the transcriptional and post-transcriptional regulation of key components in the nitrate signaling pathway, namely, NRT1.1, NLP7, and CIPK23, under abiotic stresses. …”
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    Finding Balance in Adversity: Nitrate Signaling as the Key to Plant Growth, Resilience, and Stress Response
  14. 12334
    “…Additionally, increased absorption of solar radiation acted to dampen Pacific ocean heat content discharge. …”
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    Unprecedented 2015/2016 Indo‐Pacific Heat Transfer Speeds Up Tropical Pacific Heat Recharge
  15. 12335
    “…Target of rapamycin (TOR) acts as a master regulator to control cell growth by integrating nutrient, energy, and growth factors in all eukaryotic species. …”
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    Expression profiling and functional analysis reveals that TOR is a key player in regulating photosynthesis and phytohormone signaling pathways in Arabidopsis
  16. 12336
    “…Brown adipose tissue sympathetic innervation through norepinephrine release not only induces brown adipocyte lipolysis and thermogenesis, but also acts as the major determinant of tissue mass, cellularity and mitochondrial content. …”
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    Regulation of brown adipose tissue recruitment, metabolism and thermogenic function by peroxisome proliferator-activated receptor γ
  17. 12337
    “…Increasing evidence suggests that the primary female sex hormone estrogen plays an active role in this process. This research points out on the role of estrogen during lizard spermatogenesis by using three experimental approaches: (1) exposure to an analogue of nonsteroidal estrogen as Clomiphene citrate that acts both as estrogen agonist and antagonist; (2) exposure to the gonadotropin FSH; and (3) exposures to FSH followed by Clomiphene. …”
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    Exploring the Role of Estrogens in Lizard Spermatogenesis through the Study of Clomiphene and FSH Effects
  18. 12338
    “…EMSA and transcriptional activation analysis revealed that MYB2 acted as an upstream activator and directly regulated expression of the proteases CEP1 and βVPE. …”
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    MYB2 Is Important for Tapetal PCD and Pollen Development by Directly Activating Protease Expression in Arabidopsis
  19. 12339
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    Linc00473 potentiates cholangiocarcinoma progression by modulation of DDX5 expression via miR-506 regulation
  20. 12340
    “…Non-crossover (NCO) events also occurred in the two hotspots but at very different levels (local CO/NCO ratios of 1/1 and 30/1) and their track lengths were quite small (a few hundred base pairs). …”
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    Contrasted Patterns of Crossover and Non-crossover at Arabidopsis thaliana Meiotic Recombination Hotspots
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