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  1. 12361
    “…Our results show that, like other YUCs, CKRC2/YUC8 is a rate-limiting enzyme for catalyzing the conversion of indole-3-pyruvic acid (IPyA) to indole-3-acetic acid (IAA), acting downstream of CKRC1/TAA1 in the IPyA pathway. …”
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    Functional roles of Arabidopsis CKRC2/YUCCA8 gene and the involvement of PIF4 in the regulation of auxin biosynthesis by cytokinin
  2. 12362
    “…Corn sheath blight, caused by AG1-IA, a fusion group of Rhizoctonia solani, which acts as a kind of necrotrophic fungal pathogen, poses a global threat to the production of Zea mays. …”
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    An Aminobutyric Acid Transaminase in Zea mays Interacts With Rhizoctonia solani Cellulase to Participate in Disease Resistance
  3. 12363
    “…In Arabidopsis thaliana (Arabidopsis), the transcription factor PHR1 acts as a Pi central regulator. PHL1 is a homolog of PHR1 and also plays a role in maintaining Pi homeostasis. …”
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    OsPHR3 affects the traits governing nitrogen homeostasis in rice
  4. 12364
    “…Taken together, these data suggest that Mib2 plays a critical role in synaptic plasticity and spatial memory through the Notch signaling pathway.…”
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    Mind Bomb-2 Regulates Hippocampus-dependent Memory Formation and Synaptic Plasticity
  5. 12365
    “…Melanoma differentiation-associated gene-9 (MDA-9)/Syntenin is a novel therapeutic target because it plays critical roles in cancer progression and exosome biogenesis. …”
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    MDA-9/Syntenin-Slug transcriptional complex promote epithelial-mesenchymal transition and invasion/metastasis in lung adenocarcinoma
  6. 12366
    “…Elevated levels of ROS acting as intracellular signal transducers result in autophagy, which plays a dual role in periodontitis by promoting cell death or blocking apoptosis in infected cells. …”
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    The Role of Reactive Oxygen Species and Autophagy in Periodontitis and Their Potential Linkage
  7. 12367
    “…We show that the microphthalmia-associated transcription factor (Mitf) plays a central role in intrinsic plasticity of olfactory bulb (OB) projection neurons. …”
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    Mitf Links Neuronal Activity and Long-Term Homeostatic Intrinsic Plasticity
  8. 12368
    “…Oxygen plays an important role in diverse biological processes. …”
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    Osteoclasts adapt to physioxia perturbation through DNA demethylation
  9. 12369
    “…Blockade of miR124 function abolishes the homeostatic response, whereas miR124 overexpression leads to earlier induction of homeostatic plasticity. miR124 transcription is controlled by an inhibitory transcription factor EVI1, acting by association with the deacetylase HDAC1. …”
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    MicroRNA miR124 is required for the expression of homeostatic synaptic plasticity
  10. 12370
    “…TCF4 also plays an important role in the development and functioning of the immune system. …”
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    The subcellular localization of bHLH transcription factor TCF4 is mediated by multiple nuclear localization and nuclear export signals
  11. 12371
    “…Moreover, it acts as a primary defense signal during plant stress. …”
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    The Ethylene Precursor ACC Affects Early Vegetative Development Independently of Ethylene Signaling
  12. 12372
    “…Using a null allele of the gli2a gene induced by targeted mutagenesis, we show that Gli2a is completely dispensable in the fish but acts redundantly with Gli1 to regulate expression of known Hh targets, such as ptch2, prdm1a and eng2a, in the myotome and neural tube. …”
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    Targeted inactivation and identification of targets of the Gli2a transcription factor in the zebrafish
  13. 12373
    “…Oxidative stress (OS) plays a key role in retinal dysfunctions and acts as a major trigger of inflammatory and neurodegenerative processes in several retinal diseases. …”
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    A Nature-Inspired Nrf2 Activator Protects Retinal Explants from Oxidative Stress and Neurodegeneration
  14. 12374
    “…These data suggested that TMEM30A plays a crucial role in renal tubules. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12882-023-03299-8.…”
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    Knockdown of TMEM30A in renal tubular epithelial cells leads to reduced glucose absorption
  15. 12375
    “…Monocytes’ infiltration into the tumor tissue and their activation to tumor-associated macrophages is an essential step in tumor development, also playing a critical role in an eventual metastasis. …”
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    Insulin secretagogue use and circulating inflammatory C–C chemokine levels in breast cancer patients
  16. 12376
    “…Specific inhibition of roscovitine majors target CDK 1, 2, 5, 7, and 9 showed that these CDKs played key roles in inflammatory processes of NVU cells and leucocytes after brain lesions, including ischemic stroke. …”
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    Cellular and Molecular Mechanisms of R/S-Roscovitine and CDKs Related Inhibition under Both Focal and Global Cerebral Ischemia: A Focus on Neurovascular Unit and Immune Cells
  17. 12377
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    New Aspects of the Antioxidant Activity of Glycyrrhizin Revealed by the CIDNP Technique
  18. 12378
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    Usnic Acid extends healthspan and improves the neurodegeneration diseases via mTOR/PHA-4 signaling pathway in Caenorhabditis elegans
  19. 12379
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    Functions, mechanisms, and therapeutic implications of METTL14 in human cancer
  20. 12380
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    Protective role of VEGF/VEGFR2 signaling against high fatality associated with hepatic encephalopathy via sustaining mitochondrial bioenergetics functions
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