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  1. 12401
    “…On the other hand, 3-Methylhistidine is a valuable biomarker for detecting increased muscle catabolism, as it is excreted through urine during muscle degradation. In addition, IGF-1, whose concentration in plasma is stimulated by food intake, is associated with the loss of skeletal muscle mass, which probably plays a crucial role in the progression of sarcopenia. …”
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    Nutritional and Nutrition-Related Biomarkers as Prognostic Factors of Sarcopenia, and Their Role in Disease Progression
  2. 12402
    por Needles, Burton M.
    Publicado 2018
    “…The CDH1 gene encodes for E-cadherin, which plays a role in cell–cell adhesions and acts as a tumor suppressor when expressed normally. …”
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    Journey from oncologist to cancer survivor and patient advocate in the era of precision medicine
  3. 12403
    “…In interaction with plants, a dpp1-overexpressing transformant acted as a sensitizing agent in that it up-regulated expression of plant defense salicylate-related genes in the presence of a fungal plant pathogen. …”
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    Effect of Farnesol in Trichoderma Physiology and in Fungal–Plant Interaction
  4. 12404
    “…According to a systematic phylogenetic classification with a previously reported species, the sunflower PM H(+)-ATPase genes (HHAs) were divided into four sub-clusters (I, II, IV, and V). In addition, systematic bioinformatics analyses such as gene structure analysis, chromosome location analysis, subcellular localization predication, conserved motifs, and Cis-acting elements of promoter identification were also done. …”
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    Genome-Wide Identification and Analysis of P-Type Plasma Membrane H(+)-ATPase Sub-Gene Family in Sunflower and the Role of HHA4 and HHA11 in the Development of Salt Stress Resistance
  5. 12405
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    Drosophila Strip serves as a platform for early endosome organization during axon elongation
  6. 12406
    “…RIG-I-MAVS signaling pathway plays a crucial role in defending against pathogen infection and maintaining immune balance. …”
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    WDR77 inhibits prion-like aggregation of MAVS to limit antiviral innate immune response
  7. 12407
    “…This was shown to be independent of IRF1, IRF3, or p65, canonical transcription factors necessary for activation of both type I and III interferon promoters. …”
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    DNA-PKcs restricts Zika virus spreading and is required for effective antiviral response
  8. 12408
    por Skrzypek, Klaudia, Majka, Marcin
    Publicado 2020
    “…It usually acts as a gene repressor, but it may also activate the expression of genes. …”
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    Interplay among SNAIL Transcription Factor, MicroRNAs, Long Non-Coding RNAs, and Circular RNAs in the Regulation of Tumor Growth and Metastasis
  9. 12409
    “…hnRNPK is a multifunctional protein that plays an important role in cancer cell proliferation and metastasis via its RNA- and DNA-binding properties. …”
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    hnRNPK-derived cell-penetratingpeptide inhibits cancer cell survival
  10. 12410
    por Sun, Xiaoyue, Zhang, Jing, Cao, Chunwei
    Publicado 2022
    “…The 3D genome organization and its dynamic modulate genome function, playing a pivotal role in cell differentiation and development. …”
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    CTCF and Its Partners: Shaper of 3D Genome during Development
  11. 12411
    “…RESULTS: In total, we screened 88 WP-related targets, 1480 pSS-related targets, and 32 overlapping targets. D-D-I-T Network analysis displayed six main active ingredients of WP, which played a significant therapeutic role in pSS. …”
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    Potential Mechanisms of White Peony against Primary Sjögren's Syndrome Based on Network Pharmacology and Molecular Docking
  12. 12412
    “…To assess responses to low-dose ionizing radiation (LD-IR) exposures potentially encountered during medical diagnostic procedures, nuclear accidents or terrorist acts, a quantitative proteomic approach was used to identify changes in protein abundance in a reconstituted human skin tissue model treated with 0.1 Gy of ionizing radiation. …”
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    Quantitative Proteomic Profiling of Low-Dose Ionizing Radiation Effects in a Human Skin Model
  13. 12413
    “…Heat shock protein 90 (HSP90) plays an essential role in lung adenocarcinoma, acting as a key chaperone involved in the correct functioning of numerous highly relevant protein drivers of this disease. …”
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    Identification of Predictive Biomarkers of Response to HSP90 Inhibitors in Lung Adenocarcinoma
  14. 12414
    “…The gene expression program induced by NRF2 transcription factor plays a critical role in cell defense responses against a broad variety of cellular stresses, most importantly oxidative stress. …”
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    Role of NRF2 in Lung Cancer
  15. 12415
    “…Recent studies indicate that uPAR acts a crucial part in cell migration and the modulation of bone homeostasis. …”
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    Ulinastatin Inhibits Osteoclastogenesis and Suppresses Ovariectomy-Induced Bone Loss by Downregulating uPAR
  16. 12416
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    Genetic and environmental variation in condition, cutaneous immunity, and haematocrit in house wrens
  17. 12417
    “…In 2D cultures, rhIL-6 acted in a pro-apoptotic manner and decreased the expression of ATP-binding cassette transporter G2 (ABCG2). …”
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    Protein- and growth-modulatory effects of carcinoma-associated fibroblasts on breast cancer cells: Role of interleukin-6
  18. 12418
    “…In addition to genetic aberrations, DNA methylation also acts as an epigenetic modifier to drive the onset and progression of cancer by mediating the reversible transcription of related genes. …”
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    Regulation of Canonical Oncogenic Signaling Pathways in Cancer via DNA Methylation
  19. 12419
    “…The biological network analysis showed that HJJPD plays a role in treating leptin resistance in simple obesity by acting on multiple targets in the JAK2-STAT3 pathway via various components. …”
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    Study on the Effect and Mechanism of Huaji Jianpi Decoction on Simple Obesity
  20. 12420
    “…The mammalian tumor necrosis factor-α-induced protein 8-likes (TIPEs) family plays critical roles in balancing cancer cell death and survival. …”
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    TIPE3 represses head and neck squamous cell carcinoma progression via triggering PGAM5 mediated mitochondria dysfunction
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