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  1. 12681
    “…Mechanistically, miR-10b-3p acted as cancer-promoting gene by targeting testis specific 10. …”
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    Online Artículo Texto
    Hypoxia-induced microRNA-10b-3p promotes esophageal squamous cell carcinoma growth and metastasis by targeting TSGA10
  2. 12682
    por Allain, Kristi A.
    Publicado 2020
    “…In light of these mixed messages, this paper explores how older men understand their bodies through their participation in the seemingly risky sport of ice hockey. I conducted eighteen semi-structured interviews with older Canadian men who played hockey, identifying common themes related to aging, embodiment, risk and pleasure. …”
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    Online Artículo Texto
    Winter of our contentment: Examining risk, pleasure, and emplacement in later-life physical activity
  3. 12683
    “…In this study, 80 female cancer survivors participated in a running-based group intervention (2 sessions/week; 1.5 h), while 51 acted as controls. The intervention lasted approximately 5 months. …”
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    Online Artículo Texto
    Psychological Benefits of a Sport-Based Program for Female Cancer Survivors: The Role of Social Connections
  4. 12684
    “…Previous studies have demonstrated that inflammation plays a critical role in hippocampcal damage and cognitive dysfunction induced by convulsive status epilepticus (CSE). …”
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    Online Artículo Texto
    Long non-coding RNA H19 alleviates hippocampal damage in convulsive status epilepticus rats through the nuclear factor-kappaB signaling pathway
  5. 12685
    “…The observed suppressed transcriptome networks were associated with a reduction in NK cells, macrophages, and CD4(+) T cells in the b1/2-ARs KO chimera colon. Thus, sympathetic regulation of BM-derived immune cells plays a significant role in modifying inflammatory networks in the colon and the gut microbiota composition. …”
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    Online Artículo Texto
    Shifts in the Gut Microbiota Composition Due to Depleted Bone Marrow Beta Adrenergic Signaling Are Associated with Suppressed Inflammatory Transcriptional Networks in the Mouse Colon
  6. 12686
    “…Here, we demonstrate that Oryza sativa LEAF and TILLER ANGLE INCREASED CONTROLLER (LIC) acts as an antagonistic transcription factor of BRASSINAZOLE-RESISTANT 1 (BZR1) to attenuate the BR signaling pathway. …”
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    Online Artículo Texto
    Dynamics of Brassinosteroid Response Modulated by Negative Regulator LIC in Rice
  7. 12687
    “…In addition, we demonstrate that the abundant PDR-1 plays a role in alpha-Synuclein processing. Conclusions: These data show that the abundant reporter of  C. elegans Parkin affects the autophagy-lysosomal system together with alpha-Synuclein processing which can help in understanding the pathology in Parkin-related diseases.…”
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    Fluorescent reporter of  Caenorhabditis elegans Parkin: Regulators of its abundance and role in autophagy-lysosomal dynamics
  8. 12688
    por Lu, Te-Ling, Wu, Sheng-Nan
    Publicado 2023
    “…Dexamethasone, a synthetic glucocorticoid, can directly enhance the open probability of large-conductance Ca(2+)-activated K(+) channels. Sparsentan, a dual-acting antagonist of the angiotensin II receptor and endothelin type A receptors, was found to suppress the amplitude of peak and late I(Na) effectively. …”
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    Online Artículo Texto
    Investigating the Impact of Selective Modulators on the Renin–Angiotensin–Aldosterone System: Unraveling Their Off-Target Perturbations of Transmembrane Ionic Currents
  9. 12689
    “…Some of the amino acids which tolerated any substitution but no deletion are simply acting as "spacers" to localize important residues in the protein structure.…”
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    The effect of amino acid deletions and substitutions in the longest loop of GFP
  10. 12690
    “…These data together strongly suggest that delta opioid peptide DADLE acts through the NGF-induced functional G protein-coupled Oprd1 to provide its neuroprotective and differentiating effects at least in part by regulating survival and differentiating MAPK and PI3K/Akt signaling pathways in NGF-responsive rodent neuronal cells.…”
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    Online Artículo Texto
    Crosstalk between Delta Opioid Receptor and Nerve Growth Factor Signaling Modulates Neuroprotection and Differentiation in Rodent Cell Models
  11. 12691
    “…Three agents neutralizing IL-17 (i.e., secukinumab and ixekizumab) or antagonizing its receptor (i.e., brodalumab) are currently being tested for efficacy and safety in the treatment of plaque psoriasis and PsA. …”
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    Online Artículo Texto
    Efficacy and Safety of Secukinumab in Chronic Plaque Psoriasis and Psoriatic Arthritis Therapy
  12. 12692
    “…In this study, we tested whether DTL acts as a cancer-promoting gene through its activation/overexpression in gastric cancer (GC). …”
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    Overexpression of denticleless E3 ubiquitin protein ligase homolog (DTL) is related to poor outcome in gastric carcinoma
  13. 12693
    “…Our work identifies a new cis-acting mutation interfering with Kcnq1ot1 silencing function and establishes a novel critical developmental role for the transcription factor ASCL2.…”
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    Transcription factor ASCL2 is required for development of the glycogen trophoblast cell lineage
  14. 12694
    “…Environmental temperature plays a role in the variation of blood pressure. …”
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    Online Artículo Texto
    Prenatal cold exposure causes hypertension in offspring by hyperactivity of the sympathetic nervous system
  15. 12695
    “…To solidify knowledge and promote practice of learned skills, a 30-minute interactive role-playing session followed where participants acted as observer, patient, or provider in three distinct clinical scenarios pertaining to dermatologic care of LGBTQ patients. …”
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    Interactive Session for Residents and Medical Students on Dermatologic Care for Lesbian, Gay, Bisexual, Transgender, and Queer Patients
  16. 12696
    “…[Image: see text] Oil palm (Elaeis guineensis) has proven to be a phytolith-occluded carbon (PhytOC)-rich species that plays a vital role in acting as a carbon sink for reducing atmospheric carbon dioxide (CO(2)) concentration. …”
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    Online Artículo Texto
    Phytolith-Occluded Carbon Sequestration Potential of Oil Palm Plantation in Tamil Nadu
  17. 12697
    “…Here, we report that indole modulated phage resistance of Pseudomonas aeruginosa PAO1. Specifically, we found that the type IV pilus (T4P) acts as an important receptor for P. aeruginosa phages vB_Pae_S1 and vB_Pae_TR, and indole could protect P. aeruginosa against phage infection via decreasing the T4P-mediated phage adsorption. …”
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    Online Artículo Texto
    Pseudomonas aeruginosa Resists Phage Infection via Eavesdropping on Indole Signaling
  18. 12698
    “…BACKGROUND: Guanine nucleotide exchange factors (GEFs) activate small GTPases that are involved in several cellular functions. cAMP-guanine nucleotide exchange factor II (cAMP-GEF II) acts as a target for cAMP independently of protein kinase A (PKA) and functions as a GEF for Rap1 and Rap2. …”
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    Online Artículo Texto
    Involvement of cAMP-guanine nucleotide exchange factor II in hippocampal long-term depression and behavioral flexibility
  19. 12699
    “…These results illustrated that SlMED18 plays an essential role in regulating plant internode elongation and leaf expansion in tomato plants and it acts as a key positive regulator of gibberellins biosynthesis and signal transduction as well as auxin proper transport signalling. …”
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    Online Artículo Texto
    Silencing SlMED18, tomato Mediator subunit 18 gene, restricts internode elongation and leaf expansion
  20. 12700
    “…NF-κB and activator protein-1 (AP-1) activity was regulated by the manipulation of CD36 expression in LPS-induced pGMECs. …”
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    Online Artículo Texto
    CD36 regulates lipopolysaccharide-induced signaling pathways and mediates the internalization of Escherichia coli in cooperation with TLR4 in goat mammary gland epithelial cells
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