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  1. 12761
    “…1. Polar auxin transport (PAT) plays key roles in the regulation of plant growth and development. …”
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    Kaempferol 3-O-rhamnoside-7-O-rhamnoside is an endogenous flavonol inhibitor of polar auxin transport in Arabidopsis shoots
  2. 12762
    “…Additionally, a large number of pollen-specific cis-acting elements were found in promoters of differentially expressed genes (DEG), which verified that these significantly differentially expressed genes after self-pollination (SP) were likely to participate in the self-incompatibility (SI) process, including gene encoding ARC1, a well-known downstream protein of SI in B. oleracea. …”
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    Genome-Wide Distribution, Expression and Function Analysis of the U-Box Gene Family in Brassica oleracea L.
  3. 12763
    “…Hypoxia inducible factor-1 alpha (HIF-1α) signaling is a central axis that activates oncogenic signaling and acts as a metabolic switch in endothelial cell (EC) driven tumor angiogenesis. …”
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    Anti-Angiogenic Effects of Phytochemicals on miRNA Regulating Breast Cancer Progression
  4. 12764
    “…PEC measurements in the presence of NaNO(2), acting as a suitable hole scavenger ensuring enhanced photocurrent generation compared with that of water oxidation while minimizing dark currents, allowed us to elucidate the role that molybdenum incorporation plays on the charge separation efficiency in the bulk and on the charge injection efficiency at the photoanode surface. …”
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    Effective Visible Light Exploitation by Copper Molybdo-tungstate Photoanodes
  5. 12765
    “…The causes and pathophysiology of AS are still largely unknown. The lncRNA H19 plays key roles in the pathogenesis of AS by mediating inflammatory progression by acting in the axis of IL-17A/IL-23. …”
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    Assessment of Circulating lncRNA H19 in Ankylosing Spondylitis Patients and Its Correlation with Disease Activity
  6. 12766
    “…ZMYM2 is a zinc finger transcriptional regulator that plays a key role in promoting and maintaining cell identity. …”
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    ZMYM2 controls human transposable element transcription through distinct co-regulatory complexes
  7. 12767
    “…Prostaglandin E (PGE)2 produced by osteoblasts acts as a potent stimulator of bone resorption. Inflammatory bone loss is accompanied by osteoclast formation induced by bone-resorbing cytokines, but the mechanism of PGE2 production and bone resorption in vivo is not fully understood. …”
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    An Essential Role of Cytosolic Phospholipase A2α in Prostaglandin E2–mediated Bone Resorption Associated with Inflammation
  8. 12768
    “…Activation of PI3K/Akt signaling plays a critical role in the proliferation and survival of HCC cells. …”
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    Synergistic growth inhibition by acyclic retinoid and phosphatidylinositol 3-kinase inhibitor in human hepatoma cells
  9. 12769
    “…The insulin-like growth factor binding protein 5 (IGFBP5), which is often dysregulated in human cancers, plays a crucial role in carcinogenesis and cancer development. …”
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    Insulin-like growth factor binding protein 5 (IGFBP5) functions as a tumor suppressor in human melanoma cells
  10. 12770
    “…Next, we ascertain that the up-regulation of the Na(+)/H(+) exchanger-1 (NHE-1) induced by aldosterone involves MR and GPER. …”
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    GPER is involved in the stimulatory effects of aldosterone in breast cancer cells and breast tumor-derived endothelial cells
  11. 12771
    “…Co-immunoprecipitation (Co-IP) also confirmed that there was an interaction between PmDDX41 and STING after stimulation with poly(dA:dT) but not poly(I:C). Our study is the first to demonstrate that PmDDX41 acts as a cytosolic DNA sensor that interacts with STING via its DEADc domain to trigger the IFN-β and NF-κB signaling pathways, thus activating antiviral innate immune responses.…”
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    A Cytosolic Sensor, PmDDX41, Binds Double Stranded-DNA and Triggers the Activation of an Innate Antiviral Response in the Shrimp Penaeus monodon via the STING-Dependent Signaling Pathway
  12. 12772
    “…Desmoglein 3 (Dsg3) plays a crucial role in cell-cell adhesion and tissue integrity. …”
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    Evidence for the Desmosomal Cadherin Desmoglein-3 in Regulating YAP and Phospho-YAP in Keratinocyte Responses to Mechanical Forces
  13. 12773
    “…p62/sequestosome-1 is a scaffolding protein involved in diverse cellular processes such as autophagy, oxidative stress, cell survival and death. …”
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    The Deubiquitinating Enzyme USP20 Regulates the TNFα-Induced NF-κB Signaling Pathway through Stabilization of p62
  14. 12774
    “…In HepG2 cells, SGL 121 acted as an antioxidant, a hepatoprotectant, and had an anti-lipogenic effect. …”
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    SGL 121 Attenuates Nonalcoholic Fatty Liver Disease through Adjusting Lipid Metabolism Through AMPK Signaling Pathway
  15. 12775
    por Sha, L, Dey, P, Khess, CR, Khitiz, KK
    Publicado 2021
    “…BACKGROUND: Craving plays an important role in maintenance of alcohol dependence. …”
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    The association of plasma acyl ghrelin level with alcohol craving in early abstinent alcohol dependent patients
  16. 12776
    “…During EMT, cellular reprogramming is orchestrated by core EMT transcription factors (EMT-TFs), namely ZEB1/2, TWIST1/2, SNAI1 (SNAIL) and SNAI2 (SLUG). …”
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    Long Non-Coding RNAs as Potential Regulators of EMT-Related Transcription Factors in Colorectal Cancer—A Systematic Review and Bioinformatics Analysis
  17. 12777
    “…Vesicular nucleotide transporter (VNUT), an active transporter for nucleotides in secretory vesicles, is responsible for the vesicular storage of ATP and plays an essential role in purinergic chemical transmission. …”
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    Is the vesicular nucleotide transporter a molecular target of eicosapentaenoic acid?
  18. 12778
    por Johansen, Jacob Graversen
    Publicado 2013
    “…The experimental study of exotic nuclei plays an important part in the understanding of nuclear structure. …”
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    Transfer reaction study of neutron rich beryllium isotopes
  19. 12779
    “…In this regard, the activation of liver resident macrophages, namely Kupffer cells, plays a vital role in liver inflammation and fibrosis. …”
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    Exploring the potential of treating chronic liver disease targeting the PI3K/Akt pathway and polarization mechanism of macrophages
  20. 12780
    “…Molecular docking shows that the binding energies of eight taxanes with TP53, EGFR, and AKT1 targets were less than −8.8 kcal/mol, taxanes acts on TP53, EGFR, and AKT1 targets through pathways in cancer, proteoglycans in cancer pathway and microRNAs in cancer pathway, and plays a role in treating lung cancer in biological functions such as protein binding, enzyme binding, and identical protein binding.…”
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    Mechanism of Taxanes in the Treatment of Lung Cancer Based on Network Pharmacology and Molecular Docking
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