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  1. 12841
    “…Angiotensin converting enzyme (ACE), a key enzyme of the classical RAS, converts angiotensin I (Ang I) to angiotensin II (Ang II), which acts via the Ang II type 1 receptor (AT1R) to stimulate hepatic fibrosis and increase intrahepatic vascular tone and portal pressure. …”
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    Update on New Aspects of the Renin-Angiotensin System in Hepatic Fibrosis and Portal Hypertension: Implications for Novel Therapeutic Options
  2. 12842
    “…In addition, we constructed a 12-NFMG (ADCY3, AHCY, CHDH, GUCY1A2, ITPA, MTHFD2, NRP1, POLA1, POLR1A, POLR3A, POLR3K, and SRM) risk score. …”
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    NF-κB-Related Metabolic Gene Signature Predicts the Prognosis and Immunotherapy Response in Gastric Cancer
  3. 12843
    “…The two nanofibrous morphologies (quasi-core–shell and fibril-like ones) improve the delamination resistance differently, also suggesting that the way the rubber is located in the nanofibers plays a role in the toughening action. …”
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    Self-Assembled NBR/Nomex Nanofibers as Lightweight Rubbery Nonwovens for Hindering Delamination in Epoxy CFRPs
  4. 12844
    “…SIMPLE SUMMARY: Trehalase plays a vital role in carbohydrate metabolism in insects. …”
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    Parasitoid Wasps Can Manipulate Host Trehalase to the Benefit of Their Offspring
  5. 12845
    “…Egg production performance plays an important role in the poultry industry across the world. …”
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    Integration of transcriptome sequencing and whole genome resequencing reveal candidate genes in egg production of upright and pendulous-comb chickens
  6. 12846
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    Nerve growth factor: role in growth, differentiation and controlling cancer cell development
  7. 12847
    por Li, Tian, Sun, Xiangzhou, Xu, Kewei
    Publicado 2018
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    The suppressing role of miR-622 in renal cell carcinoma progression by down-regulation of CCL18/MAPK signal pathway
  8. 12848
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    Exopolysaccharides amylovoran and levan contribute to sliding motility in the fire blight pathogen Erwinia amylovora
  9. 12849
    “…To give insight on the causes of this TE activation, we performed a TE transcriptomic analysis in ovaries (notorious for playing a major role in TE silencing) of parental species and their F1 and backcrossed (BC) hybrids. …”
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    Transposable Element Misregulation Is Linked to the Divergence between Parental piRNA Pathways in Drosophila Hybrids
  10. 12850
    “…It targets cell cycle progression through ubiquitin mediated degradation of G1-checkpoint CDK inhibitors—p21 (CDKN1A) and p27 (CDKN1B). …”
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    Curcumin-Mediated Degradation of S-Phase Kinase Protein 2 Induces Cytotoxic Effects in Human Papillomavirus-Positive and Negative Squamous Carcinoma Cells
  11. 12851
    “…Molecular docking showed that I-SPD, Pachypodol and Vestitol in XFBD played a role in treating COVID-19 by acting on NLRP3, CSF2, and relieve the clinical symptoms of SARS-CoV-2 infection. …”
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    Exploring the mechanism of action of Xuanfei Baidu granule (XFBD) in the treatment of COVID-19 based on molecular docking and molecular dynamics
  12. 12852
    “…In conclusion, our study presents the first evidence that NCgl2478 protects against various stresses by acting as an MSH-dependent thiol–disulfide reductase, belonging to a novel DsbA–Mrx1 cluster.…”
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    A novel mycothiol-dependent thiol–disulfide reductase in Corynebacterium glutamicum involving oxidative stress resistance
  13. 12853
    “…Eye contact is a dynamic social signal that captures attention and plays a critical role in human communication. In particular, direct gaze often accompanies communicative acts in an ostensive function: a speaker directs her gaze towards the addressee to highlight the fact that this message is being intentionally communicated to her. …”
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    When eyes beat lips: speaker gaze affects audiovisual integration in the McGurk illusion
  14. 12854
    “…The observation that the nucleus is surrounded by its own putative Ca(2+) store raises the possibility that nuclear IP(3)-dependent Ca(2+) release plays a critical role in ETC. This provides a potential mechanism of regulation that acts locally and autonomously from the global cytosolic Ca(2+) signal underlying ECC. …”
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    Calcium and IP3 dynamics in cardiac myocytes: experimental and computational perspectives and approaches
  15. 12855
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    A soil-carrying lacewing larva in Early Cretaceous Lebanese amber
  16. 12856
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    Effect of circadian rhythm on NAD and other metabolites in human brain
  17. 12857
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    Investing in the future: lessons learnt from communicating the results of HSV/ HIV intervention trials in South Africa
  18. 12858
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    Dysregulation of autophagy as a common mechanism in lysosomal storage diseases
  19. 12859
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    The effects of haploid selection on Y chromosome evolution in two closely related dioecious plants
  20. 12860
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    A role for placental kisspeptin in β cell adaptation to pregnancy
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