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  1. 13121
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    Cholesterol depletion enhances TGF-β Smad signaling by increasing c-Jun expression through a PKR-dependent mechanism
  2. 13122
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    CARMA3/NF-κB signaling contributes to tumorigenesis of hepatocellular carcinoma and is inhibited by sodium aescinate
  3. 13123
    “…In conclusion, HSP70 modulates NF-κB activation in AM of TB patients, through inhibiting IκB-α phosphorylation or acting as a chaperon molecule to prevent NF-κB binding to the target genes by facilitating degradation. …”
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    Heat shock protein70 is implicated in modulating NF-κB activation in alveolar macrophages of patients with active pulmonary tuberculosis
  4. 13124
    “…Kisspeptin-10 (KP-10) acts as a tumor metastasis suppressor via its receptor, G-protein-coupled receptor 54 (GPR54). …”
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    Kisspeptin-10 (KP-10) stimulates osteoblast differentiation through GPR54-mediated regulation of BMP2 expression and activation
  5. 13125
    “…Calreticulin (CRT) is a highly conserved protein in the endoplasmic reticulum that plays important roles in the regulation of key cellular functions. …”
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    Entamoeba histolytica Calreticulin Induces the Expression of Cytokines in Peripheral Blood Mononuclear Cells Isolated From Patients With Amebic Liver Abscess
  6. 13126
    “…Transforming growth factor β (TGF-β) serves critical functions in brain injury, especially in cerebral ischemia; however, apart from its neuroprotective effects, its role in regulating neurogenesis is unclear. TGF-β acts in different ways; the most important, canonical TGF-β activity involves TGF-β receptor I (TβRI) or the activin receptor-like kinase 5 (ALK5) signaling pathway. …”
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    ALK5 signaling pathway mediates neurogenesis and functional recovery after cerebral ischemia/reperfusion in rats via Gadd45b
  7. 13127
    “…On the other hand, this study has shown that while healthcare workers acted as epidemic attenuators, hospitalized patients played the role of an epidemic amplifier.…”
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    Individual and network characteristic associated with hospital-acquired Middle East Respiratory Syndrome coronavirus
  8. 13128
    “…BACKGROUND: Ovarian retinoid homeostasis plays an important role in the physiological function of the ovary. …”
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    Regulation by FSH of the dynamic expression of retinol-binding protein 4 in the mouse ovary
  9. 13129
    “…NOD-like receptor pyrin domain containing 3 (NLRP3) is a microbial and danger signal sensor that acts as a regulator of inflammation via activation of Caspase-1 (CASP1) and has been identified as a major contributor to human liver diseases. …”
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    Significance of elevated serum and hepatic NOD-like receptor pyrin domain containing 3 (NLRP3) in hepatitis C virus-related liver disease
  10. 13130
    “…METHODS: In the present study, we have assessed the role played by endogenous SP/NK-1R interactions in damaging CNS inflammation in an established rhesus macaque model that faithfully reproduces the key clinical features of Lyme neuroborreliosis, using the specific NK-1R antagonist, aprepitant. …”
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    Aprepitant limits in vivo neuroinflammatory responses in a rhesus model of Lyme neuroborreliosis
  11. 13131
    “…BACKGROUND: Dulaglutide, a long-acting glucagon-like peptide-1 receptor agonist (GLP-1RA), has been shown to reduce body weight and liver fat content in patients with type 2 diabetes. …”
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    Dulaglutide Ameliorates Palmitic Acid-Induced Hepatic Steatosis by Activating FAM3A Signaling Pathway
  12. 13132
    “…BACKGROUND: Polygalacturonase (PG), as an important hydrolase participating in the degradation of pectin, plays an important role in softening process of fruit. …”
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    Genome-wide analysis of polygalacturonase gene family from pear genome and identification of the member involved in pear softening
  13. 13133
    “…Overexpression of Gm28309 or inhibition of miR-3068-5p repressed p65 phosphorylation and reduced NLRP3 inflammasome and IL-1β and IL-18 secretion. Mechanistically, Gm28309 acted as a ceRNA of miR-3068-5p to activate NF-κB pathway by targeting κB-Ras2, an inhibitor of NF-κB signaling. …”
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    Brucella-Induced Downregulation of lncRNA Gm28309 Triggers Macrophages Inflammatory Response Through the miR-3068-5p/NF-κB Pathway
  14. 13134
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    A multitask transfer learning framework for the prediction of virus-human protein–protein interactions
  15. 13135
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    Functional replacement of myostatin with GDF-11 in the germline of mice
  16. 13136
    “…The involvement of the Central Nervous System (CNS) during sepsis has received considerable attention, especially the hippocampus which plays a key role in the learning and memory processes. …”
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    Inhaled molecular hydrogen reduces hippocampal neuroinflammation, glial reactivity and ameliorates memory impairment during systemic inflammation
  17. 13137
    “…These results suggest that the NAc plays a role in differentiating somatosensory experience from social observation of aversion at a single cell level. …”
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    Nucleus accumbens core single cell ensembles bidirectionally respond to experienced versus observed aversive events
  18. 13138
    “…[Image: see text] Quantum tunneling is a fundamental phenomenon that plays a pivotal role in the motion and interaction of atoms and molecules. …”
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    Quantum Tunneling Facilitates Water Motion across the Surface of Phenanthrene
  19. 13139
    “…Neuroinflammation plays an important role in the pathogenesis of neurological disorders, and despite intensive research, treatment of neuroinflammation remains limited. …”
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    Mechanism of baixiangdan capsules on anti-neuroinflammation: combining dry and wet experiments
  20. 13140
    “…This phase modulation effectively encodes a prediction of when important events (such as stressed syllables) are likely to occur, and acts to increase sensitivity to these relevant acoustic cues. …”
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    Neural Oscillations Carry Speech Rhythm through to Comprehension
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