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  1. 13161
    “…RESULTS: The results suggest that: (i) recombination plays an important role in determining the haplotype structure of PvDBP(II), and (ii) PvDBP(II )appears to contain neutrally evolving codons as well as codons evolving under natural selection. …”
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  2. 13162
    “…Since several perturbations were found in signaling cascades in response to MG, we hereby suggest that it plays an important role in signal transduction probably acting as a stress signal molecule.…”
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  3. 13163
    “…Caffeine (10 mM) prevented neuronal cell loss in 96% of DA neurons, with a mean GFP intensity that is 40% higher than control (0.1% DMSO). To confirm if cAMP plays a role in the observed neuroprotection by caffeine, cAMP levels were elevated via forskolin (10 μM), an adenylyl cyclase activator. …”
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  4. 13164
    “…The strongest association with frailty (adjusted for age and gender) was found with the SNP rs518054 (odds ratio: 1.635, 95% CI = 1.241–2.154; p-value: 4.81 × 10(−04)) intergenic and located between LOC105375977 and C9orf146. …”
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  5. 13165
  6. 13166
    “…The structure of FHP over two phases enabled learning from phase I to be incorporated into phase II. Having the PPI representatives closely involved, developing communities of practice, and the oversight and measuring activities acted as ‘disciplinary structures’ that contributed to embedding PPI in the FHP and kept the patient experience at the forefront of the improvement initiatives.…”
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  7. 13167
  8. 13168
    “…RLS-0071 has been tested in various ex vivo and in vivo systems and has shown promise for the treatment of both immune-mediated hematological diseases where alterations in the classical complement pathway plays an important pathogenic role as well as in models of tissue-based diseases such as acute lung injury and hypoxic ischemic encephalopathy driven by both complement and neutrophil-mediated pathways (i.e., MPO activity and NET formation). …”
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  9. 13169
    “…Melanin pigment plays a critical role in the protection against the harmful effects of ultraviolet radiation and other environmental stressors. …”
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  10. 13170
    “…TEM revealed that the cell wall of ΔgemA was thicker than that of the WT strain, demonstrating that GemA plays a role in cell wall composition and integrity. …”
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  11. 13171
    “…In lifestyle-related diseases, such as cardiovascular, metabolic, respiratory, and kidney diseases, chronic inflammation plays a causal role in their pathogenesis; however, underlying mechanisms of sterile chronic inflammation are not well-understood. …”
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  12. 13172
    “…FLC expression suppresses flowering at high levels during winter; and during vernalization, B3 TFs, cold memory cis-acting element and polycomb repressive complex 1 and 2 (PRC1 and 2) silence FLC activation. …”
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  13. 13173
    “…Moreover, Sp1 site III plays a particularly important role in the recruitment of both p300 and RelA to the promoter. …”
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  14. 13174
    por Li, Z., Jackson, R.J., Ranasinghe, C.
    Publicado 2019
    “…These inhibitor studies showed that in the context of i.n. viral vector vaccination, IL-25 plays a predominant role in early ILC development/regulation than IL-33, and likely acts as a master regulator of ILC. …”
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  15. 13175
    por Durstewitz, Daniel
    Publicado 2017
    “…Interactive examples of most methods are provided through a package of MatLab routines, encouraging a playful approach to the subject, and providing readers with a better feel for the practical aspects of the methods covered.   …”
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  16. 13176
    “…Protein–protein interaction analysis revealed that the expression of the genes (OsPUB23, OsPUB24, OsPUB66, and OsPUB67) known to be involved in stress increased in PUB7-GE and this, by forming a 1-node network with OsPUB66 and OsPUB7, acted as a negative regulator of drought and salinity stress. …”
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  17. 13177
    “…OBJECTIVE: The current study describes the prevalence of sleep disorders in enuretic children, playing as influencing factors in the response to treatment and risk of relapse. …”
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  18. 13178
    “…In the case of AC and NiO, NiO plays a role of dehydrogenation, resulting in the degradation product, while AC mainly acts as carbonization promoter. …”
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  19. 13179
  20. 13180
    “…Mutations of myosin-7a cause type 1 Usher syndrome, the most common and severe form of deafblindness in humans. …”
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