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  1. 13201
    “…IMPORTANCE Heat acts as a danger signal for pathogens, especially those infecting mammalian hosts in whom fever indicates infection. …”
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    CpxAR of Actinobacillus pleuropneumoniae Contributes to Heat Stress Response by Repressing Expression of Type IV Pilus Gene apfA
  2. 13202
    “…Besides exerting a strong anti-inflammatory effects in line with the improvement of immune responses in patients undergoing dialysis, PMMA also plays a role in modulating adaptive immune response, i.e., can clear blood from soluble CD40, a natural antagonist of the CD40/CD40L signaling that acts inhibiting immunoglobulin production by B cells. …”
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    Enhancing Immune Protection in Hemodialysis Patients: Role of the Polymethyl Methacrylate Membrane
  3. 13203
    “…The phytohormone abscisic acid (ABA) plays important roles in response to abiotic and biotic stresses in plants. …”
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    PYL Family Genes from Liriodendron chinense Positively Respond to Multiple Stresses
  4. 13204
    “…The simulation results were highly consistent with the actual force applied (intraclass correlation efficient (ICC): 0.997–1.000; p < 0.001). Furthermore, through in vivo measurements and a finite element analysis, the movement trends generated when the measured orthodontic forces that acted on the teeth were simulated. …”
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    Fabrication of three-dimensional orthodontic force detecting brackets and preliminary clinical test for tooth movement simulation
  5. 13205
    “…Octadecanoic acid (C18:0) showed a significant assembling effect in the concentration range tested (0.1 to 2 insect equivalents). The very long chain hexacosanoic acid (C26:0) was significantly attractant at low doses (≤ 1 equivalent), although a repellent effect was observed at higher doses. …”
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    Epicuticular lipids induce aggregation in Chagas disease vectors
  6. 13206
    “…The protein peroxiredoxin 6 (PRDX6) plays a pleiotropic role in negatively regulating death signaling in response to stressors, and thereby stabilizes cellular homeostasis. …”
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    Neuroprotective effect of peroxiredoxin 6 against hypoxia-induced retinal ganglion cell damage
  7. 13207
    “…BACKGROUND: Over the last 30 years, extensive studies have revealed the crucial roles played by microbes in aquatic ecosystems. It has been shown that bacteria, viruses and protozoan grazers are dominant in terms of abundance and biomass. …”
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    Effect of grazers and viruses on bacterial community structure and production in two contrasting trophic lakes
  8. 13208
    “…IFN-γ production by NK cells in response to B. anthracis spores was: i) contact-dependent through RAE-1-NKG2D interaction with macrophages; ii) IL-12, IL-18, and IL-15-dependent, where IL-12 played a key role and regulated both NK cell and macrophage activation; and iii) required IL-18 for only an initial short time window. …”
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    Mechanisms of NK Cell-Macrophage Bacillus anthracis Crosstalk: A Balance between Stimulation by Spores and Differential Disruption by Toxins
  9. 13209
    “…Mannose-binding lectin (MBL) plays a key role in the activation of the lectin-complement pathway of innate immunity, and its deficiency has been linked with several acute infections. …”
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    Serum Mannose-Binding Lectin Concentration, but Not Genotype, Is Associated With Clostridium difficile Infection Recurrence: A Prospective Cohort Study
  10. 13210
    “…Upon drying at 130 °C, (NH(4))(3)AsS(3) capping ligands were converted into a thin layer of As(2)S(3), acting as an infrared-transparent semiconducting glue. …”
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    High Infrared Photoconductivity in Films of Arsenic-Sulfide-Encapsulated Lead-Sulfide Nanocrystals
  11. 13211
    “…We found that intronic Foxp3 enhancer CNS3 acts as an epigenetic switch that confers a poised state to the Foxp3 promoter in precursor cells to make Treg cell lineage commitment responsive to a broad range of TCR stimuli, particularly to suboptimal ones. …”
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    A mechanism for expansion of regulatory T cell repertoire and its role in self tolerance
  12. 13212
    “…OBJECTIVE: The GH/IGF-1 axis has important roles in growth and metabolism. …”
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    Hypothalamic growth hormone receptor (GHR) controls hepatic glucose production in nutrient-sensing leptin receptor (LepRb) expressing neurons
  13. 13213
    “…Arabidopsis microRNA169 (miR169) is an ambient temperature-responsive microRNA that plays an important role in stress responses and the floral transition. …”
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    Elongated Hypocotyl 5-Homolog (HYH) Negatively Regulates Expression of the Ambient Temperature-Responsive MicroRNA Gene MIR169
  14. 13214
    “…The invasion of extravillous trophoblast (EVT) cells into the maternal decidua, which plays a crucial role in the establishment of a successful pregnancy, is highly orchestrated by a complex array of regulatory mechanisms. …”
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    LncRNA H19-Derived miR-675-5p Accelerates the Invasion of Extravillous Trophoblast Cells by Inhibiting GATA2 and Subsequently Activating Matrix Metalloproteinases
  15. 13215
    “…Toll-like receptor 4 (TLR4) has been reported to protect against Gram-negative bacteria by acting as a pathogen recognition receptor that senses mainly lipopolysaccharide (LPS) from Gram-negative bacteria. …”
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    Toll-Like Receptor 4 Protects Against Clostridium perfringens Infection in Mice
  16. 13216
    “…We also found that D-Chiro-Ins, either alone or in combination with insulin and E2 increased the expression and activation of insulin receptor substrate-1 (IRS1) and glucose transporter type 4 (GLUT4). …”
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    D-Chiro-Inositol Regulates Insulin Signaling in Human Adipocytes
  17. 13217
    “…An OA mouse model was used for in vivo experiments, and IL-1β-induced injury of mouse chondrocytes was conducted for in vitro experiments. …”
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    Role of lincRNA-Cox2 targeting miR-150 in regulating the viability of chondrocytes in osteoarthritis
  18. 13218
    “…Among these novel and innovative treatments are immunotherapies. These therapies are playing an increasingly important role in the treatment of multiple different cancers. …”
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    The Immunotherapy Landscape in Adrenocortical Cancer
  19. 13219
    “…Interleukin-6 (IL-6) is a multipotent cytokine. IL-6 plays a dual role in inflammation through both classical signaling (IL-6 binds membrane IL-6 receptor/IL-6R) and trans-signaling (IL-6 binds soluble IL-6R). …”
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    Classical Signaling and Trans-Signaling Pathways Stimulated by Megalobrama amblycephala IL-6 and IL-6R
  20. 13220
    “…The results of this study suggest that PKCα plays an oncogenic role in this type of breast cancer model. …”
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    Deciphering the Role and Signaling Pathways of PKCα in Luminal A Breast Cancer Cells
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