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  1. 13481
    “…ABSTRACT: Previously, we discovered that 1-(3,5-dimethoxyphenyl)-3-(4-(3-methoxyphenoxy)-2-((4-morpholinophenyl)amino)pyrimidin-5-yl)urea (AKF-D52), a synthetic phenoxypyrimidine urea derivative, acts as a growth inhibitor of various cancer cell types. …”
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  2. 13482
    “…P62 regulates nuclear translocation of vimentin by controlling SUMO1 and SUMO2/3 expression. In the nucleus, vimentin acts as a transcription factor that regulates CDC42, cathepsin B, and cathepsin D to promote PDC invasion and migration. …”
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  3. 13483
    “…BACKGROUND: Mitogen-activated protein kinases (MAPKs) plays essential roles in the development, hormone regulation and abiotic stress response of plants. …”
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  4. 13484
  5. 13485
  6. 13486
  7. 13487
  8. 13488
    “…CONCLUSION: Our results demonstrated for the first time that genes related to cell death pathways exhibit stage-specific responses to PGF(2α) administration depending on its local or systemic actions. Locally-acting PGF(2α) plays a luteoprotective role by inhibiting apoptosis and necroptosis in the early CL. …”
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  9. 13489
    “…As the cell surface receptor for SARS-CoV-2 infection, the angiotensin-converting enzyme 2 (ACE2) plays a pivotal role for renal physiology and function. …”
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  10. 13490
    “…Factors influencing adherence to CPGs were categorised by assessing whether they (i) inhibited or facilitated guideline adherence, (ii) played a role in patients at risk of CCS or with suspected or known CCS, (iii) were mentioned in implicit or explicit thematic reference to CPGs, and (iv) were declared a practical problem. …”
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  11. 13491
  12. 13492
  13. 13493
    “…Playing instruments can encourage emotional expression, socialization and exploration of various therapeutic themes (i.e. conflict, communication, grief, etc.). …”
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  14. 13494
  15. 13495
    por Millan, Mark J.
    Publicado 2022
    “…Agomelatine possesses a unique binding profile, behaving as a melatonin (MT(1)/MT(2)) receptor agonist and 5-HT(2C) receptor antagonist, yet recognizing neither monoamine transporters nor GABA(A) receptors. …”
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  16. 13496
    “…Additionally, we discovered a novel compound, 13-hydroxypiericidin A 10-O-α-D-glucose (1 → 6)-β-D-glucoside (S18), in a marine-derived Streptomyces strain that bound to PTPN22 with high affinity and acted as a novel inhibitor. …”
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  17. 13497
  18. 13498
  19. 13499
  20. 13500
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