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95021por Nedergaard, Anders, Sun, Shu, Karsdal, Morten A., Henriksen, Kim, Kjær, Michael, Lou, Yunyun, He, Yi, Zheng, Qinlong, Suetta, Charlotte“…This loss was bigger in young subjects than in elderly, but whereas the young recovered almost fully, the elderly had limited regrowth of muscle. …”
Publicado 2013
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95022por Dong, Xiao-Ying, Liu, Wen-Jun, Zhao, Ming-Qiu, Wang, Jia-Ying, Pei, Jing-Jing, Luo, Yong-Wen, Ju, Chun-Mei, Chen, Jin-Ding“…PAMs derived from knockdown of both RIG-I and MDA5 almost failed to produce IFNs and inflammatory cytokines. …”
Publicado 2013
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95023“…With the advent of high-throughput genome and metagenome sequencing technologies, the development of fast, reliable and sensitive methods of ISs and MITEs detection become an important challenge. So far, almost all studies dealing with prokaryotic transposons have used classical BLAST-based detection methods against reference libraries. …”
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95024por Yatsuda, Junji, Irie, Atsushi, Harada, Kumiko, Michibata, Yayoi, Tsukamoto, Hirotake, Senju, Satoru, Tomita, Yusuke, Yuno, Akira, Hirayama, Masatoshi, Abu Sayem, Mohammad, Takeda, Naoki, Shibuya, Isao, Sogo, Shinji, Fujiki, Fumihiro, Sugiyama, Haruo, Eto, Masatoshi, Nishimura, Yasuharu“…BM-DC-based immunization of KIF20A(494-517) peptide from another TAA KIF20A, with an almost identical HLA-binding core amino acid sequence to mouse ortholog, successfully induced Th-cell responses in Tgm. …”
Publicado 2013
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95025“…CONCLUSION: This study confirmed that GEP classification of posterior uveal melanoma cells obtained by FNAB is feasible in almost all cases, including most in which FNAB yields an insufficient aspirate for cytodiagnosis. …”
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95026“…MAIN RESULTS AND THE ROLE OF CHANCE: Donors were almost evenly split between those who supported and those who rejected the recommendation to introduce legislation to remove donor anonymity with retrospective effect. …”
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95027por Thayer, Sarah, Wei, Wenhui, Buysman, Erin, Brekke, Lee, Crown, William, Grabner, Michael, Raparla, Swetha, Quimbo, Ralph, Cziraky, Mark J., Hu, Wenli, Cuddihy, Robert“…RESULTS: At baseline, almost one in three liraglutide patients (OI, n = 363; HC, n = 521) had A1C <7.0%, while insulin glargine patients (OI, n = 498; HC, n = 1,188) had poorer health status, higher A1C (insulin glargine: 9.8% and 9.1% versus liraglutide: 7.9% and 7.7%, OI and HC, respectively, both P < 0.001), and were less likely to be obese (insulin glargine: 10.8% and 9.2% versus liraglutide: 17.4% and 18.8%, OI and HC, respectively, both P < 0.01). …”
Publicado 2013
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95028por Williams, Christopher KO, Cristina Stefan, D, Rawlinson, Fiona, Simbiri, Kenneth, Mbulaiteye, Sam M“…The constant growth in the number of attendants and increasing diversity of the nations of their origin are consistent with advances, whereby the number of participants and the nations of their origin have grown from 24 in 1983 to almost 1000 in 2013, and from 14 to 70, respectively. …”
Publicado 2014
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95029por Tornaritis, Michael J, Philippou, Elena, Hadjigeorgiou, Charalambos, Kourides, Yiannis A, Panayi, Adamos, Savva, Savvas C“…RESULTS: A large percentage of children consumed less than the minimum of 45% energy (en) of carbohydrate (18.4%-66.5% in different age groups) and exceeded the recommended intakes of total fat (42.4%-83.8%), saturated fatty acids (90.4%-97.1%) and protein (65.2%-82.7%), while almost all (94.7%-100%) failed to meet the recommended fibre intake. …”
Publicado 2014
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95030por Swinnen, Thijs Willem, Scheers, Tineke, Lefevre, Johan, Dankaerts, Wim, Westhovens, Rene, de Vlam, Kurt“…The role of physical activity, defined as movement-related energy expenditure, is largely unknown and almost exclusively studied using patient-reported outcome measures. …”
Publicado 2014
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95031“…Kinetic studies showed that pol IV incorporated dCMP almost as efficiently as dTMP opposite S-cdA, whereas it incorporated the correct nucleotide dCMP opposite S-cdG 10-fold more efficiently than any other dNMP. …”
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95032por Minicuci, Nadia, Biritwum, Richard B., Mensah, George, Yawson, Alfred E., Naidoo, Nirmala, Chatterji, Somnath, Kowal, Paul“…The prevalence of current smokers was 8.1% (95% CI 7.0–9.2), while 2.0 (95% CI 1.5–2.5) were infrequent/frequent heavy drinkers, 67.9% (95% CI 65.2–70.5) consume insufficient fruits and vegetables, and 25.7% (95% CI 23.1–28.3) had a low level of physical activity. Almost 10% (95% CI 8.3–11.1) of adults were obese and 77.6% (95% CI 76.0–79.2) had a high-risk waist-to-hip ratio (WHR). …”
Publicado 2014
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95033por Ostheimer, Christian, Janich, Martin, Hübsch, Patrick, Gerlach, Reinhard, Vordermark, Dirk“…Mean and maximum brain doses were comparable and showed an almost linear decrease between min. and max. dose. …”
Publicado 2014
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95034por Klimacek, Mario, Kirl, Elisabeth, Krahulec, Stefan, Longus, Karin, Novy, Vera, Nidetzky, Bernd“…As long as glycerol constituted the main by-product energetics of anaerobic growth on xylose and glucose were almost identical. CONCLUSIONS: In just 61 generation IBB10B05, displaying ~530% improved strain fitness, was evolved from BP10001. …”
Publicado 2014
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95035por D'Huyvetter, Matthias, Vincke, Cécile, Xavier, Catarina, Aerts, An, Impens, Nathalie, Baatout, Sarah, De Raeve, Hendrik, Muyldermans, Serge, Caveliers, Vicky, Devoogdt, Nick, Lahoutte, Tony“…Most importantly, nanobody-based targeted radionuclide therapy in mice bearing small estiblashed HER2(pos) tumors led to an almost complete blockade of tumor growth and a significant difference in event-free survival between the treated and the control groups (P < 0.0001). …”
Publicado 2014
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95036“…Challenge of HSC with C5a enhanced HSC migration almost as efficiently as PDGF in a two-dimensional wound healing and Boyden chamber migration assays. …”
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95037por Liang, Jing-juan, Zhang, Mei-ling, Ding, Meng, Mai, Zhi-mao, Wu, San-xing, Du, Yue, Feng, Jia-xun“…Zymogram analysis showed that alcohol dehydrogenase 1 (KmAdh1) was largely induced during ethanol production, KmAdh4 was constitutively expressed at a lower level and KmAdh2 and KmAdh3 were almost undetectable. The genes encoding the four alcohol dehydrogenases (ADHs) were cloned from strain GX-UN120. …”
Publicado 2014
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95038por Koochekpour, Shahriar, Buckles, Erick, Shourideh, Mojgan, Hu, SiYi, Chandra, Dhyan, Zabaleta, Jovanny, Attwood, Kristopher“…However, in AAs with somatic AR mutation, the E213 G-allele distribution was almost equal to the A-allele. Silencing of one of the somatic AR mutations (i.e., 597 Ser>Gly) in a primary AA-PCa cell line (e.g., E006AA) revealed that similar AR mutation can be associated simultaneously with both “gain-of-function” phenotype (cell migration and invasion) and a “loss-of-function” phenotype (proliferation). …”
Publicado 2014
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95039por Fu, Wei, Wang, Kai, Zhao, Jun-Long, Yu, Heng-Chao, Li, San-Zhong, Lin, Yan, Liang, Liang, Huang, Si-Yong, Liang, Ying-Min, Han, Hua, Qin, Hong-Yan“…Using various truncated forms of FHL1C, we found that the RBP-J-binding motif of FHL1C had almost the same effect as full-length FHL1C on the induction of apoptosis, suggesting that the minimal functional sequence in the RBP-J-binding motif of FHL1C might be a new drug candidate for T-ALL treatment. …”
Publicado 2014
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95040“…In addition, 83.1% (113/136) in the SMS group stated that they read all or almost all the messages, compared with only 63.5% (66/104) in the email group. …”
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