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95761por Saengkaew, Tansit, Mancini, Alessandra, Ruiz-Babot, Gerard, Cabrera, Claudia P, Barnes, Michael R, Dunkel, Leo, Guasti, Leonardo, Howard, Sasha“…This analysis identified 6 rare potentially pathogenic variants in CCDC141 in 25 individuals of 8 families which account for almost 10% of self-limited DP cases in this cohort, without variants identified in cohort control cases. …”
Publicado 2021
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95762por Chen, Huan, Zhang, Yan, Liu, Mengsi, Zhang, Ziwei, Feng, Wenhuan, Li, Ping, Zhu, Dalong“…In patients with biochemical control after treatment, bone turnover markers and bone remodelling index almost decreased to normal level (all P > 0.05). Conclusion: Acromegalic patients exhibited PTH-independent calcium-phosphate alterations, enhanced bone turnover state and positive bone remodeling balance. …”
Publicado 2021
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95763por Elkhalloufi, Fahd, Boutayeb, Saber, Mamouch, Fouzia, Rakibi, Latifa, Elazzouzi, Sanae, Errihani, Hassan“…RESULTS: From a socio-economic point of view, almost all patients claim that cancer is a costly disease as well as a disease that leads to a drop in income and the inevitable impoverishment of Moroccan patients. …”
Publicado 2021
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95764“…L’observance thérapeutique n’a pas été altérée malgré les premières rumeurs concernant la corticothérapie inhalée. …”
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95765por Huang, Richard S.P., Murugesan, Karthikeyan, Montesion, Meagan, Pavlick, Dean C., Mata, Douglas A., Hiemenz, Matthew C., Decker, Brennan, Frampton, Garrett, Albacker, Lee A., Ross, Jeffrey S.“…Conversely, CD274 CN changes were not significantly correlated with tumor mutational burden in almost all the tumor types. CONCLUSION: CD274 CN changes and PD-L1 expression were highly correlated in multiple tumor types. …”
Publicado 2021
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95766“…RESULTS: Trends for YLDs counts per condition year (1990–2017) and forecasted values (2018–2022) showed an overall steady increase for all conditions, except HIV and respiratory conditions. YLDs counts almost doubled from 1990 to 2017, with a 17% predicted increase from 2017 to 2022. …”
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95767por Trick, William E., Rachman, Fred, Hinami, Keiki, Hill, Jennifer C., Conover, Craig, Diep, Lisa, Gordon, Howard S., Kho, Abel, Meltzer, David O., Shah, Raj C., Stellon, Ed, Thangaraj, Padma, Toepfer, Peter S.“…RESULTS: Among 11,447 homeless recipients of healthcare, nearly 1 in 5 were identified by ICD10 code alone without recorded homeless services (n = 2177; 19%). Almost half received homeless services that did not include stable housing (n = 5444; 48%), followed by stable housing (n = 3017; 26%), then receipt of both stable and unstable services (n = 809; 7%). …”
Publicado 2021
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95768“…More than 50% of the patients had improvements in KCCQ‐OSS by ≥5 (60.4%; 95% CI 47.4–72.1) and 10 points (50.5%; 95% CI 34.9–66.0) at 12 months. Almost half of the patients experienced a ≥1 class improvement in NYHA class after implantation of the device at 1 month (67.9%; 95% CI 37.3–88.3) and at 12 months (48.8%; 95% CI 31.8–66.2). …”
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95769por Lloret-Villas, Audald, Bhati, Meenu, Kadri, Naveen Kumar, Fries, Ruedi, Pausch, Hubert“…Genome-wide association studies between imputed sequence variant genotypes and six dairy traits as well as stature produced almost identical results from both assemblies. CONCLUSIONS: The ARS-UCD1.2 and UOA_Angus_1 assemblies are suitable for reference-guided genome analyses in Brown Swiss cattle. …”
Publicado 2021
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95770por Nasser, Mouhamad, Larrieu, Sophie, Boussel, Loic, Si-Mohamed, Salim, Bazin, Fabienne, Marque, Sébastien, Massol, Jacques, Thivolet-Bejui, Françoise, Chalabreysse, Lara, Maucort-Boulch, Delphine, Hachulla, Eric, Jouneau, Stéphane, Le Lay, Katell, Cottin, Vincent“…RESULTS: We identified a total of 14,413 patients with PF-ILD. Almost half of them (48.1%) were female and the mean (± standard deviation) age was 68.4 (± 15.0) years. …”
Publicado 2021
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95771por Polychronopoulou, Kyriaki, AlKhoori, Ayesha A., Efstathiou, Angelos M., Jaoude, Maguy Abi, Damaskinos, C. M., Baker, Mark A., Almutawa, Alia, Anjum, Dalaver H., Vasiliades, Michalis A., Belabbes, Abderrezak, Vega, Lourdes F., Zedan, Abdallah Fathy, Hinder, Steven J.“…Also, copper compensates almost three times more charge (0.37e(−)) compared to Co and Mn, ca. 0.13e(−) and 0.10e(−), respectively, corroborating for its tendency to be reduced. …”
Publicado 2021
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95772por Zhou, Xue-Quan, Carbo-Bague, Imma, Siegler, Maxime A., Hilgendorf, Jonathan, Basu, Uttara, Ott, Ingo, Liu, Rongfang, Zhang, Liyan, Ramu, Vadde, IJzerman, Adriaan P., Bonnet, Sylvestre“…On the other hand, unlike [2]Cl, [1]Cl aggregated into nanoparticles in FCS-containing medium, which resulted in much more efficient gold cellular uptake. [1]Cl had much more selective anticancer properties than [2]Cl and cisplatin, as it was almost 10 times more cytotoxic to human cancer cells (A549, A431, A375, and MCF7) than to noncancerous cells (MRC5). …”
Publicado 2021
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95773por Armas Rojas, Nurys B, Lacey, Ben, Soni, Monica, Charles, Shaquille, Carter, Jennifer, Varona-Pérez, Patricia, Burrett, Julie Ann, Martínez, Marcy Calderón, Lorenzo-Vázquez, Elba, Constantén, Sonia Bess, Taylor, Hannah, Sherliker, Paul, Rigau, José Manuel Morales, Ross, Stephanie, Massa, M. Sofia, López, Osvaldo Jesús Hernández, Islam, Nazrul, Morales, Miguel Ángel Martínez, Alomá, Ismell Alonso, Estupiñan, Fernando Achiong, González, Mayda Díaz, Muñoz, Noel Rosquete, Asencio, Marelis Cendra, Díaz-Diaz, Oscar, Iglesias-Marichal, Ileydis, Emberson, Jonathan, Peto, Richard, Lewington, Sarah“…The association with BMI and cardiovascular mortality was almost completely attenuated following adjustment for the mediating effect of SBP. …”
Publicado 2021
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95774por Belsti, Yitayeh, Gela, Yibeltal Yismaw, Akalu, Yonas, Dagnew, Baye, Getnet, Mihret, Abdu Seid, Mohammed, Diress, Mengistie, Yeshaw, Yigizie, Fekadu, Sofonias Addis“…One-third of respondents, 32.2% (n = 381), reported that COVID-19 vaccines are safe. Almost all 94.9% (n = 1124) responded that health workers should be vaccinated first. …”
Publicado 2021
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95775por Xu, Jie, Liu, Lingjuan, Xiong, Jie, Zhang, Lu, Huang, Peng, Tang, Li, Xiao, Yangyang, Li, Xingfang, Li, Jian, Luo, Yingying, Li, Huiling, Mao, Dingan, Liu, Liqun“…Bilateral optic neuritis (BON) was the most common initial phenotype in the pediatric group but less common in the adult group (28.57 vs. 0%, p = 0.0119). Almost half of the adult patients presented with neuromyelitis optica spectrum disease (NMOSD), which was less prevalent among the pediatrics (48 vs. 21.43%, p = 0.0414). …”
Publicado 2021
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95776“…The preoperative O and H parameters showed strong to almost perfect agreement (intraclass correlation coefficient for A = 0.858 [95% CI: 0.738 to 0.923, P < .001], intraclass correlation coefficient for B = 0.955 [95% CI: 0.918 to 0.976, P < .001]). …”
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95777por Thomas-Hargreaves, Lewis R., Giansiracusa, Marcus J., Gregson, Matthew, Zanda, Emanuele, O'Donnell, Felix, Wooles, Ashley J., Chilton, Nicholas F., Liddle, Stephen T.“…For 2Dy–4Dy, the Dy-components can be grouped into 2Dy–cation/4Dy and 2Dy–anion/3Dy, where the former have almost linear C[double bond, length as m-dash]Dy[double bond, length as m-dash]C units with short average Dy[double bond, length as m-dash]C distances, and the latter have more bent C[double bond, length as m-dash]Dy[double bond, length as m-dash]C units with longer average Dy[double bond, length as m-dash]C bonds. …”
Publicado 2021
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95778por Doisne, Nicolas, Grauso, Marta, Mougenot, Nathalie, Clergue, Michel, Souil, Charlotte, Coulombe, Alain, Guicheney, Pascale, Neyroud, Nathalie“…The full-length hSCN5A-gfp expression was assessed by western blot and immunohistochemistry in transduced heart tissues and the Na(+) current was recorded by the patch-clamp technique in isolated adult GFP-expressing heart cells. RESULTS: Almost 75% of the cardiomyocytes were transduced in hearts of mice injected with hNa(v)1.5 and ∼30% in hNa(v)1.5-R104W overexpressing tissues. …”
Publicado 2021
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95779por Kebede, Mebratu Abraha, Demissie, Dereje Bayissa, Guddu, Dessalegn Kenay, Haile, Michael Temane, Bitew, Zebenay Workneh, Muleta, Mahteme Bekele“…CONCLUSION: The current study revealed that a high proportion of front line a negative emotional responses had negative emotional response. Further, almost all of the medical staffs working in COVID-19 treatment centers and at obstetrics emergency and abortion care unit had perceived the outbreak related stressors. …”
Publicado 2021
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95780por Tyrovolas, Stefanos, Giné-Vázquez, Iago, Fernández, Daniel, Morena, Marianthi, Koyanagi, Ai, Janko, Mark, Haro, Josep Maria, Lin, Yang, Lee, Paul, Pan, William, Panagiotakos, Demosthenes, Molassiotis, Alex“…Globally, population mobility to parks and similar leisure areas during at least a minimum of implemented intermediate-level control policies (when compared to low-level control policies) was related to accelerated COVID-19 spread. Results were almost consistent when regional stratified analysis was applied. …”
Publicado 2021
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