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  1. 96461
    “…IMPORTANCE: Bothrops venom acts almost immediately at the bite site and causes tissue damage. …”
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    Photobiomodulation Therapy to Treat Snakebites Caused by Bothrops atrox: A Randomized Clinical Trial
  2. 96462
    “…We show that the phyletic patterns (patterns of presence-absence in completely sequenced genomes) of almost 90% of the COGs are inconsistent with the hypothetical species tree. …”
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    Algorithms for computing parsimonious evolutionary scenarios for genome evolution, the last universal common ancestor and dominance of horizontal gene transfer in the evolution of prokaryotes
  3. 96463
    “…Results for Study 3 indicated that changing a website from video- to audio-rich content reduced the bandwidth requirement by almost 50%, but it remained too large to allow satisfactory use in dial-up modem scenarios. …”
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    Bandwidth Constraints to Using Video and Other Rich Media in Behavior Change Websites
  4. 96464
    por Slaga, T. J.
    Publicado 1983
    “…Our present understanding of two-stage carcinogenesis encompasses almost four decades of research. Evidence for chemical promotion or cocarcinogenesis was first provided by Berenblum, who reported that a regimen of croton oil (weak or noncarcinogenic) applied alternately with small doses of benzo(a)pyrene (BP) to mouse skin induced a larger number of tumors than BP alone. …”
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    Overview of tumor promotion in animals
  5. 96465
    “…We found an indication for BRCA1 methylation to be associated with AI at the BRCA1 locus. Almost all BRCA1 methylated tumours with absent/markedly reduced BRCA1 expression (8/9) displayed BRCA1 deletion. …”
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    Epigenetic silencing and deletion of the BRCA1 gene in sporadic breast cancer
  6. 96466
    “…Yet the complete set of these homeobox genes was maintained, albeit distributed over almost twice the number of chromosomes. Selection due to dosage effects and/or stoichiometric disturbance might act more strongly to maintain a modal number of homeobox genes (and possibly transcription factors more generally) per genome, yet permit the accumulation of other (non regulatory) genes associated with these homeobox gene clusters.…”
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    Comparative genomics of ParaHox clusters of teleost fishes: gene cluster breakup and the retention of gene sets following whole genome duplications
  7. 96467
    “…E. cuniculi lacks MAP kinase cascades and almost all protein kinases that are involved in stress responses, ion homeostasis and nutrient signalling in the model fungi S. cerevisiae and S. pombe, including AMPactivated protein kinase (Snf1), previously thought to be ubiquitous in eukaryotes. …”
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    The complement of protein kinases of the microsporidium Encephalitozoon cuniculi in relation to those of Saccharomyces cerevisiae and Schizosaccharomyces pombe
  8. 96468
    Publicado 1992
    “…The intravenous sensitization of C57BL/6 (B6) mice with class I H-2- disparate B6-C-H-2bm1 (bm1) spleen cells results in almost complete abrogation of anti-bm1 CD8+ helper (proliferative and interleukin 2- producing) T cell (Th) activities. …”
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    Cell-cell interaction in graft rejection responses: induction of anti- allo-class I H-2 tolerance is prevented by immune responses against allo-class II H-2 antigens coexpressed on tolerogen
  9. 96469
    por Opie, Eugene L., Barker, Bertha I.
    Publicado 1908
    “…With advance of caseation its activity diminishes so that tissue which has undergone almost complete caseation exhibits trivial evidence of the presence of enzyme. …”
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    ENZYMES OF TUBERCULOUS TISSUE
  10. 96470
    por Carrel, Alexis, Hartmann, Alice
    Publicado 1917
    “…Surface wounds, deep-seated wounds, and osseous cavities, which had previously been either completely or almost completely sterilized, could be maintained for days and even weeks in a condition of surgical asepsis by the use of a paste containing 7 and 10 parts per 1,000 of chloramine-T. …”
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    CICATRIZATION OF WOUNDS : VII. STERILIZATION OF WOUNDS WITH CHLORAMINE-T.
  11. 96471
    por Cecil, Russell L., Vaughan, Henry F.
    Publicado 1919
    “…Among unvaccinated, it was 31.8 per cent, almost three times as great. On the other hand, the mortality rate in pneumonia secondary to influenza is about the same for the vaccinated and unvaccinated groups. 10. …”
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    RESULTS OF PROPHYLACTIC VACCINATION AGAINST PNEUMONIA AT CAMP WHEELER
  12. 96472
    por Friedewald, William F., Rous, Peyton
    Publicado 1944
    “…The connective tissue of the corium is so slowly excited by the pure hydrocarbons that for a long while it furnishes to most of the growths only a scanty stroma, when any, and in consequence they remain small,—low, dry, indolent, bas-relief affairs, made up almost entirely of the neoplastic epithelium,—not florid, fleshy excrescences with a large connective tissue component, such as tarring calls forth. …”
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    THE DETERMINING INFLUENCE OF TAR, BENZPYRENE, AND METHYLCHOLANTHRENE ON THE CHARACTER OF THE BENIGN TUMORS INDUCED THEREWITH IN RABBIT SKIN
  13. 96473
    “…During the first 12 h of the inflammatory response the production rate was increased 1.5 times and then leveled off, reaching almost the normal rate after 24 h. Furthermore, the excellent agreement between the results of the two methods of calculation for the normal steady state confirmed once more that the promonocyte is the direct precursor cell of the monocyte, giving rise to the two monocytes after each division. …”
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    QUANTITATIVE STUDY ON THE PRODUCTION AND KINETICS OF MONONUCLEAR PHAGOCYTES DURING AN ACUTE INFLAMMATORY REACTION
  14. 96474
    “…A strongly alkaline solution (pH 11.0) is almost as toxic as a strongly acid one, although in distilled water the organisms survive fairly well at this reaction. …”
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    STUDIES ON SALT ACTION : X. THE INFLUENCE OF ELECTROLYTES UPON THE VIABILITY AND ELECTROPHORETIC MIGRATION OF BACTERIUM COLI.
  15. 96475
    “…AMD473 naked-DNA binding was significantly less affected (P < 0.05) than that of cisplatin by the presence of 5 mM glutathione. Also, AMD473 almost completely circumvented acquired cisplatin resistance in a cell line (A2780cisR) with fivefold elevated intracellular glutathione levels compared with the parent A2780 cell line when measured by clonogenic assay (RF 4.5 for AMD473 vs RF 18 for cisplatin). …”
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    In vitro circumvention of cisplatin resistance by the novel sterically hindered platinum complex AMD473.
  16. 96476
    por Fearon, DT, Austen, KF
    Publicado 1977
    “…Under conditions in which the control proteins, C3bINA and β1H, almost completely inactivated C3b bound to sheep erythrocytes (E(s)), which does not activate the alternative pathway, the function of C3b bound to E(r) was diminished by less than one-fifth. …”
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    Activation of the alternative complement pathway with rabbit erythrocytes by circumvention of the regulatory action of endogenous control proteins
  17. 96477
    Publicado 1981
    “…When PMN were incubated with the bivalent anti-C3b receptor at 37 rather than at 0 degree C, almost no immunofluorescence was observed, which indicates that the C3b receptor-F(ab')2 complexes had been rendered inaccessible to TRITC-IgG anti-F(ab')2. …”
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    Membrane distribution and adsorptive endocytosis by C3b receptors on human polymorphonuclear leukocytes
  18. 96478
    “…BACKGROUND: The use of nicotine replacement therapy (NRT) can almost double the chances of success for smokers to quit. …”
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    Pharmacokinetics, safety and efficacy from randomized controlled trials of 1 and 2 mg nicotine bitartrate lozenges (Nicotinell(®))
  19. 96479
    “…The Arbacia cytochrome oxidase was strongly inhibited by carbon monoxide in the dark, the inhibition being almost completely reversed by light. The inhibition constant was not greatly altered by variation in the concentration of cytochrome c or the concentration of hydroquinone used as reductant for the cytochrome c, having a value of 3 to 5 under the conditions used. …”
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    STUDIES ON CELL METABOLISM AND CELL DIVISION : V. CYTOCHROME OXIDASE ACTIVITY IN THE EGGS OF ARBACIA PUNCTULATA
  20. 96480
    “…Computer-aided detection was almost as sensitive as DOUBLE but significantly more specific. …”
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    Comparison of standard and double reading and computer-aided detection (CAD) of interval cancers at prior negative screening mammograms: blind review
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