A Very Long-acting Exatecan and Its Synergism with DNA Damage Response Inhibitors

por Fontaine, Shaun D., Carreras, Christopher W., Reid, Ralph R., Ashley, Gary W., Santi, Daniel V.
Publicado 2023

Reprogramming of Tumor-reactive Tumor-infiltrating Lymphocytes to Human-induced Pluripotent Stem Cells

por Islam, S.M. Rafiqul, Maeda, Takuya, Tamaoki, Naritaka, Good, Meghan L., Kishton, Rigel J., Paria, Biman C., Yu, Zhiya, Bosch-Marce, Marta, Bedanova, Nicole M., Liu, Chengyu, Kruhlak, Michael J., Restifo, Nicholas P., Vizcardo, Raul
Publicado 2023

Enhanced Detection of Landmark Minimal Residual Disease in Lung Cancer Using Cell-free DNA Fragmentomics

por Wang, Siwei, Xia, Zhijun, You, Jing, Gu, Xiaolan, Meng, Fanchen, Chen, Peng, Tang, Wanxiangfu, Bao, Hua, Zhang, Jingyuan, Wu, Xue, Shao, Yang, Wang, Jie, Zuo, Xianglin, Xu, Lin, Yin, Rong
Publicado 2023

Targeting CHAF1B Enhances IFN Activity against Myeloproliferative Neoplasm Cells

por Saleiro, Diana, Kosciuczuk, Ewa M., Fischietti, Mariafausta, Perez, Ricardo E., Yang, G. Sohae, Eckerdt, Frank, Beauchamp, Elspeth M., Hou, Ye, Wang, Qixuan, Weinberg, Rona Singer, Fish, Eleanor N., Yue, Feng, Hoffman, Ronald, Platanias, Leonidas C.
Publicado 2023

Racial/Ethnic Disparities in Cervical Cancer Stage at Diagnosis: Mediating Effects of Neighborhood-level Socioeconomic Deprivation

por Sokale, Itunu O., Oluyomi, Abiodun O., Montealegre, Jane R., Thrift, Aaron P.
Publicado 2023

Preclinical Profile of BYON3521 Predicts an Effective and Safe MET Antibody–Drug Conjugate

por Groothuis, Patrick G., Jacobs, Daniëlle C.H., Hermens, Inge A.T., Damming, Désirée, Berentsen, Kim, Mattaar-Hepp, Ellen, Stokman, Marloes E.M., van Boekel, Tinie, Rouwette, Myrthe, van der Vleuten, Monique A.J., Sesink, Aloys, Dijcks, Fred A., Coumans, Ruud G.E., Schouten, Jan, Glaudemans, Dirk H., van Wijk, Daniëlle, Blomenröhr, Marion, Kappers, Wendela A., Ubink, Ruud, van der Lee, Miranda M.C., Dokter, Wim H.A.
Publicado 2023

Somatic Mosaic Chromosomal Alterations and Death of Cardiovascular Disease Causes among Cancer Survivors

por Sun, Maxine, Cyr, Marie-Christyne, Sandoval, Johanna, Lemieux Perreault, Louis-Philippe, Busque, Lambert, Tardif, Jean-Claude, Dubé, Marie-Pierre
Publicado 2023

Tumor Mutational Burden as a Predictor of Survival with Durvalumab and/or Tremelimumab Treatment in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

por Wildsmith, Sophie, Li, Weimin, Wu, Song, Stewart, Ross, Morsli, Nassim, Raja, Rajiv, Zhang, Qu, Ye, Jiabu, He, Philip, Shetty, Jagdish, Yovine, Alejandro, Holoweckyj, Nicholas, Real, Katia, Walker, Jill, Wrona, Magdalena, de los Reyes, Melissa, Barker, Craig, Whiteley, Jessica, Haddad, Robert, Licitra, Lisa, Ferris, Robert, Fayette, Jérôme, Zandberg, Dan P., Siu, Lillian L., Mesía, Ricard
Publicado 2023

BLEACH&STAIN 15-marker Multiplexed Imaging in 3,098 Human Carcinomas Reveals Six Major PD-L1–driven Immune Phenotypes with Distinct Spatial Orchestration

por Bady, Elena, Möller, Katharina, Mandelkow, Tim, Raedler, Jonas B., Yang, Cheng, Ebner, Julia, Lurati, Magalie C.J., Simon, Ronald, Vettorazzi, Eik, Büscheck, Franziska, Luebke, Andreas M., Dum, David, Menz, Anne, Sauter, Guido, Höflmayer, Doris, Weidemann, Sören, Fraune, Christoph, Uhlig, Ria, Bernreuther, Christian, Jacobsen, Frank, Clauditz, Till S., Wilczak, Waldemar, Burandt, Eike, Steurer, Stefan, Minner, Sarah, Lennartz, Maximilian, Blessin, Niclas C.
Publicado 2023

Exploring the Complex Relationship between Gut Microbiota and Risk of Colorectal Neoplasia Using Bidirectional Mendelian Randomization Analysis

por Li, Wanxin, Zhou, Xuan, Yuan, Shuai, Wang, Lijuan, Yu, Lili, Sun, Jing, Chen, Jie, Xiao, Qian, Wan, Zhongxiao, Zheng, Ju-Sheng, Zhang, Cai-Xia, Larsson, Susanna C., Farrington, Susan M., Law, Philip, Houlston, Richard S., Tomlinson, Ian, Ding, Ke-Feng, Dunlop, Malcolm G., Theodoratou, Evropi, Li, Xue
Publicado 2023

A Phase II Trial of Guadecitabine plus Atezolizumab in Metastatic Urothelial Carcinoma Progressing after Initial Immune Checkpoint Inhibitor Therapy

por Jang, H. Josh, Hostetter, Galen, Macfarlane, Alexander W., Madaj, Zachary, Ross, Eric A., Hinoue, Toshinori, Kulchycki, Justin R., Burgos, Ryan S., Tafseer, Mahvish, Alpaugh, R. Katherine, Schwebel, Candice L., Kokate, Rutika, Geynisman, Daniel M., Zibelman, Matthew R., Ghatalia, Pooja, Nichols, Peter W., Chung, Woonbok, Madzo, Jozef, Hahn, Noah M., Quinn, David I., Issa, Jean-Pierre J., Topper, Michael J., Baylin, Stephen B., Shen, Hui, Campbell, Kerry S., Jones, Peter A., Plimack, Elizabeth R.
Publicado 2023

A Tumor-suppressive Molecular Axis EP300/circRERE/miR-6837-3p/MAVS Activates Type I IFN Pathway and Antitumor Immunity to Suppress Colorectal Cancer

por Ding, Nan, You, A-Bin, Yang, Hu, Hu, Guo-Sheng, Lai, Chun-Ping, Liu, Wen, Ye, Feng
Publicado 2023

Predicting the Abscopal Effect: Associated Tumor Histologic Subtypes and Biomarkers

por Nelson, Blessie Elizabeth, Adashek, Jacob J., Sheth, Aakash Akshay, Subbiah, Vivek
Publicado 2023

Activating an Adaptive Immune Response with a Telomerase-Mediated Telomere Targeting Therapeutic in Hepatocellular Carcinoma

por Mender, Ilgen, Siteni, Silvia, Barron, Summer, Flusche, Ann Marie, Kubota, Naoto, Yu, Chunhua, Cornelius, Crystal, Tedone, Enzo, Maziveyi, Mazvita, Grichuk, Anthony, Venkateswaran, Niranjan, Conacci-Sorrell, Maralice, Hoshida, Yujin, Kang, Rui, Tang, Daolin, Gryaznov, Sergei, Shay, Jerry W.
Publicado 2023

JMJD6 Shapes a Pro-tumor Microenvironment via ANXA1-Dependent Macrophage Polarization in Breast Cancer

por Cioni, Bianca, Ratti, Silvia, Piva, Annamaria, Tripodi, Irene, Milani, Matteo, Menichetti, Francesca, Langella, Tiziana, Botti, Laura, De Cecco, Loris, Chiodoni, Claudia, Lecis, Daniele, Colombo, Mario P.
Publicado 2023

Preclinical Efficacy of the Antibody–Drug Conjugate CLDN6–23-ADC for the Treatment of CLDN6-Positive Solid Tumors

por McDermott, Martina S.J., O'Brien, Neil A., Hoffstrom, Benjamin, Gong, KeWei, Lu, Ming, Zhang, Jun, Luo, Tong, Liang, Min, Jia, Weiping, Hong, Jenny J., Chau, Kevin, Davenport, Simon, Xie, Bin, Press, Michael F., Panayiotou, Richard, Handly-Santana, Abram, Brugge, Joan S., Presta, Leonard, Glaspy, John, Slamon, Dennis J.
Publicado 2023

Nuclear Export Inhibitor Selinexor Enhances Oncolytic Myxoma Virus Therapy against Cancer

por Rahman, Masmudur M., van Oosterom, Fleur, Enow, Junior A., Hossain, Maksuda, Gutierrez-Jensen, Ami D., Cashen, Mackenzie, Everts, Anne, Lowe, Kenneth, Kilbourne, Jacquelyn, Daggett-Vondras, Juliane, Karr, Timothy L., McFadden, Grant
Publicado 2023

Categorizing Risks within Barrett's Esophagus To Guide Surveillance and Interception; Suggesting a New Framework

por Honing, Judith, Fitzgerald, Rebecca C.
Publicado 2023

Influence of Adipose Tissue Distribution, Sarcopenia, and Nutritional Status on Clinical Outcomes After CD19 CAR T-cell Therapy

por Rejeski, Kai, Cordas dos Santos, David M., Parker, Nathan H., Bücklein, Veit L., Winkelmann, Michael, Jhaveri, Khushali S., Liu, Lian, Trinkner, Paul, Günther, Sophie, Karschnia, Philipp, Blumenberg, Viktoria, Schmidt, Christian, Kunz, Wolfgang G., von Bergwelt-Baildon, Michael, Jain, Michael D., Theurich, Sebastian, Subklewe, Marion
Publicado 2023

The Immunopeptidome from a Genomic Perspective: Establishing the Noncanonical Landscape of MHC Class I–Associated Peptides

por Bedran, Georges, Gasser, Hans-Christof, Weke, Kenneth, Wang, Tongjie, Bedran, Dominika, Laird, Alexander, Battail, Christophe, Zanzotto, Fabio Massimo, Pesquita, Catia, Axelson, Håkan, Rajan, Ajitha, Harrison, David J., Palkowski, Aleksander, Pawlik, Maciej, Parys, Maciej, O'Neill, J. Robert, Brennan, Paul M., Symeonides, Stefan N., Goodlett, David R., Litchfield, Kevin, Fahraeus, Robin, Hupp, Ted R., Kote, Sachin, Alfaro, Javier A.
Publicado 2023