Tamoxifen Response at Single-Cell Resolution in Estrogen Receptor–Positive Primary Human Breast Tumors

por Kim, Hyunsoo, Whitman, Austin A., Wisniewska, Kamila, Kakati, Rasha T., Garcia-Recio, Susana, Calhoun, Benjamin C., Franco, Hector L., Perou, Charles M., Spanheimer, Philip M.
Publicado 2023

The Tumor Immune Microenvironment Architecture Correlates with Risk of Recurrence in Head and Neck Squamous Cell Carcinoma

por Weed, Donald T., Zilio, Serena, McGee, Christie, Marnissi, Boutheina, Sargi, Zoukaa, Franzmann, Elizabeth, Thomas, Giovana, Leibowitz, Jason, Nicolli, Elizabeth, Arnold, David, Bicciato, Silvio, Serafini, Paolo
Publicado 2023

Circulating Tumor DNA Analysis in Advanced Urothelial Carcinoma: Insights from Biological Analysis and Extended Clinical Follow-up

por Lindskrog, Sia V., Birkenkamp-Demtröder, Karin, Nordentoft, Iver, Laliotis, George, Lamy, Philippe, Christensen, Emil, Renner, Derrick, Andreasen, Tine G., Lange, Naja, Sharma, Shruti, ElNaggar, Adam C., Liu, Minetta C., Sethi, Himanshu, Aleshin, Alexey, Agerbæk, Mads, Jensen, Jørgen B., Dyrskjøt, Lars
Publicado 2023

Upregulation of Indoleamine 2,3-Dioxygenase 1 in Tumor Cells and Tertiary Lymphoid Structures is a Hallmark of Inflamed Non–Small Cell Lung Cancer

por Bessede, Alban, Peyraud, Florent, Le Moulec, Sylvestre, Cousin, Sophie, Cabart, Mathilde, Chomy, François, Rey, Christophe, Lara, Oren, Odin, Ophélie, Nafia, Imane, Guegan, Jean-Philippe, Italiano, Antoine
Publicado 2023

Analysis and Visualization of Longitudinal Genomic and Clinical Data from the AACR Project GENIE Biopharma Collaborative in cBioPortal

por de Bruijn, Ino, Kundra, Ritika, Mastrogiacomo, Brooke, Tran, Thinh Ngoc, Sikina, Luke, Mazor, Tali, Li, Xiang, Ochoa, Angelica, Zhao, Gaofei, Lai, Bryan, Abeshouse, Adam, Baiceanu, Diana, Ciftci, Ersin, Dogrusoz, Ugur, Dufilie, Andrew, Erkoc, Ziya, Garcia Lara, Elena, Fu, Zhaoyuan, Gross, Benjamin, Haynes, Charles, Heath, Allison, Higgins, David, Jagannathan, Prasanna, Kalletla, Karthik, Kumari, Priti, Lindsay, James, Lisman, Aaron, Leenknegt, Bas, Lukasse, Pieter, Madela, Divya, Madupuri, Ramyasree, van Nierop, Pim, Plantalech, Oleguer, Quach, Joyce, Resnick, Adam C., Rodenburg, Sander Y.A., Satravada, Baby A., Schaeffer, Fedde, Sheridan, Robert, Singh, Jessica, Sirohi, Rajat, Sumer, Selcuk Onur, van Hagen, Sjoerd, Wang, Avery, Wilson, Manda, Zhang, Hongxin, Zhu, Kelsey, Rusk, Nicole, Brown, Samantha, Lavery, Jessica A., Panageas, Katherine S., Rudolph, Julia E., LeNoue-Newton, Michele L., Warner, Jeremy L., Guo, Xindi, Hunter-Zinck, Haley, Yu, Thomas V., Pilai, Shirin, Nichols, Chelsea, Gardos, Stuart M., Philip, John, Kehl, Kenneth L., Riely, Gregory J., Schrag, Deborah, Lee, Jocelyn, Fiandalo, Michael V., Sweeney, Shawn M., Pugh, Trevor J., Sander, Chris, Cerami, Ethan, Gao, Jianjiong, Schultz, Nikolaus
Publicado 2023

FF-10850, a Novel Liposomal Topotecan Achieves Superior Antitumor Activity via Macrophage- and Ammonia-Mediated Payload Release in the Tumor Microenvironment

por Shimoyama, Susumu, Okada, Ken, Kimura, Toshifumi, Morohashi, Yasushi, Nakayama, Shinji, Kemmochi, Sayaka, Makita-Suzuki, Keiko, Matulonis, Ursula A., Mori, Mikinaga
Publicado 2023

The Next-Generation Oral Selective Estrogen Receptor Degrader Camizestrant (AZD9833) Suppresses ER(+) Breast Cancer Growth and Overcomes Endocrine and CDK4/6 Inhibitor Resistance

por Lawson, Mandy, Cureton, Natalie, Ros, Susana, Cheraghchi-Bashi, Azadeh, Urosevic, Jelena, D'Arcy, Sophie, Delpuech, Oona, DuPont, Michelle, Fisher, David I., Gangl, Eric T., Lewis, Hilary, Trueman, Dawn, Wali, Neha, Williamson, Stuart C., Moss, Jennifer, Montaudon, Elodie, Derrien, Heloise, Marangoni, Elisabetta, Miragaia, Ricardo J., Gagrica, Sladjana, Morentin-Gutierrez, Pablo, Moss, Thomas A., Maglennon, Gareth, Sutton, Daniel, Polanski, Radoslaw, Rosen, Alan, Cairns, Jonathan, Zhang, Pei, Sánchez-Guixé, Mònica, Serra, Violeta, Critchlow, Susan E., Scott, James S., Lindemann, Justin P.O., Barry, Simon T., Klinowska, Teresa, Morrow, Christopher J., S Carnevalli, Larissa
Publicado 2023

Olaparib and Ceralasertib (AZD6738) in Patients with Triple-Negative Advanced Breast Cancer: Results from Cohort E of the plasmaMATCH Trial (CRUK/15/010)

por Ring, Alistair, Kilburn, Lucy S., Pearson, Alex, Moretti, Laura, Afshari-Mehr, Angelica, Wardley, Andrew M., Gurel, Bora, Macpherson, Iain R., Riisnaes, Ruth, Baird, Richard D., Martin, Sue, Roylance, Rebecca, Johnson, Hannah, Ferreira, Ana, Winter, Matthew C., Dunne, Kathryn, Copson, Ellen, Hickish, Tamas, Burcombe, Russell, Randle, Kat, Serra, Violeta, Llop-Guevara, Alba, Bliss, Judith M., Turner, Nicolas C.
Publicado 2023

Fatty Acid Oxidation Mediated by Malonyl-CoA Decarboxylase Represses Renal Cell Carcinoma Progression

por Zhou, Lijie, Luo, Yongbo, Liu, Yuenan, Zeng, Youmiao, Tong, Junwei, Li, Mengting, Hou, Yaxin, Du, Kaixuan, Qi, Yabin, Pan, Wenbang, Liu, Yuanhao, Wang, Rongli, Tian, Fengyan, Gu, Chaohui, Chen, Ke
Publicado 2023

Fibroblast Activation Protein-Targeted Radioligand Therapy with (177)Lu-EB-FAPI for Metastatic Radioiodine-Refractory Thyroid Cancer: First-in-Human, Dose-Escalation Study

por Fu, Hao, Huang, Jingxiong, Zhao, Tianzhi, Wang, Hongjian, Chen, Yuhang, Xu, Weizhi, Pang, Yizhen, Guo, Wei, Sun, Long, Wu, Hua, Xu, Pengfei, Su, Bishan, Zhang, Jingjing, Chen, Xiaoyuan, Chen, Haojun
Publicado 2023

PERK Inhibition by HC-5404 Sensitizes Renal Cell Carcinoma Tumor Models to Antiangiogenic Tyrosine Kinase Inhibitors

por Stokes, Michael E., Calvo, Veronica, Fujisawa, Sho, Dudgeon, Crissy, Huang, Sharon, Ballal, Nupur, Shen, Leyi, Gasparek, Jennifer, Betzenhauser, Matthew, Taylor, Simon J., Staschke, Kirk A., Rigby, Alan C., Mulvihill, Mark J., Bose, Nandita, Lightcap, Eric S., Surguladze, David
Publicado 2023

Randomized Phase II Trial of Dendritic Cell/Myeloma Fusion Vaccine with Lenalidomide Maintenance after Upfront Autologous Hematopoietic Cell Transplantation for Multiple Myeloma: B...

por Chung, David J., Shah, Nina, Wu, Juan, Logan, Brent, Bisharat, Lina, Callander, Natalie, Cheloni, Giulia, Anderson, Kenneth, Chodon, Thinle, Dhakal, Binod, Devine, Steve, Somaiya Dutt, Poorvi, Efebera, Yvonne, Geller, Nancy, Ghiasuddin, Haider, Hematti, Peiman, Holmberg, Leona, Howard, Alan, Johnson, Bryon, Karagkouni, Dimitra, Lazarus, Hillard M., Malek, Ehsan, McCarthy, Philip, McKenna, David, Mendizabal, Adam, Nooka, Ajay, Munshi, Nikhil, O'Donnell, Lynn, Rapoport, Aaron P., Reese, Jane, Rosenblatt, Jacalyn, Soiffer, Robert, Stroopinsky, Dina, Uhl, Lynne, Vlachos, Ioannis S., Waller, Edmund K., Young, James W., Pasquini, Marcelo C., Avigan, David
Publicado 2023

Efficacy of Nivolumab in Pediatric Cancers with High Mutation Burden and Mismatch Repair Deficiency

por Das, Anirban, Tabori, Uri, Sambira Nahum, Lauren C., Collins, Natalie B., Deyell, Rebecca, Dvir, Rina, Faure-Conter, Cecile, Hassall, Timothy E., Minturn, Jane E., Edwards, Melissa, Brookes, Elissa, Bianchi, Vanessa, Levine, Adrian, Stone, Simone C., Sudhaman, Sumedha, Sanchez Ramirez, Santiago, Ercan, Ayse B., Stengs, Lucie, Chung, Jill, Negm, Logine, Getz, Gad, Maruvka, Yosef E., Ertl-Wagner, Birgit, Ohashi, Pamela S., Pugh, Trevor, Hawkins, Cynthia, Bouffet, Eric, Morgenstern, Daniel A.
Publicado 2023

The BRD4–NUT Fusion Alone Drives Malignant Transformation of NUT Carcinoma

por Durall, R. Taylor, Huang, Julianna, Wojenski, Luke, Huang, Yeying, Gokhale, Prafulla C., Leeper, Brittaney A., Nash, Joshua O., Ballester, Pedro L., Davidson, Scott, Shlien, Adam, Sotirakis, Emmanuel, Bertaux, Fabien, Dubus, Vincent, Luo, Jia, Wu, Catherine J., Keskin, Derin B., Eagen, Kyle P., Shapiro, Geoffrey I., French, Christopher A.
Publicado 2023

CK1δ and CK1ε Signaling Sustains Mitochondrial Metabolism and Cell Survival in Multiple Myeloma

por Burger, Karen L., Fernandez, Mario R., Meads, Mark B., Sudalagunta, Praneeth, Oliveira, Paula S., Renatino Canevarolo, Rafael, Alugubelli, Raghunandan Reddy, Tungsevik, Alexandre, De Avila, Gabe, Silva, Maria, Graeter, Allison I., Dai, Hongyue A., Vincelette, Nicole D., Prabhu, Antony, Magaletti, Dario, Yang, Chunying, Li, Weimin, Kulkarni, Amit, Hampton, Oliver, Koomen, John M., Roush, William R., Monastyrskyi, Andrii, Berglund, Anders E., Silva, Ariosto S., Cleveland, John L., Shain, Kenneth H.
Publicado 2023

SGN-B6A: A New Vedotin Antibody–Drug Conjugate Directed to Integrin Beta-6 for Multiple Carcinoma Indications

por Lyon, Robert P., Jonas, Mechthild, Frantz, Christopher, Trueblood, Esther S., Yumul, Roma, Westendorf, Lori, Hale, Christopher J., Stilwell, Jackie L., Yeddula, Narayana, Snead, Katie M., Kumar, Vineet, Patilea-Vrana, Gabriela I., Klussman, Kerry, Ryan, Maureen C.
Publicado 2023

Unraveling Racial Disparities in Supportive Care Medication Use among End-of-Life Pancreatic Cancer Patients: Focus on Pain Management and Psychiatric Therapies

por Allen, John M., Awunti, MegCholack, Guo, Yi, Bian, Jiang, Rogers, Sherise C., Scarton, Lisa, DeRemer, David L., Wilkie, Diana J.
Publicado 2023

Genome-Wide Association and Two-Sample Mendelian Randomization Analyses of Plasma Ghrelin and Gastrointestinal Cancer Risk

por Larsson, Susanna C., Höijer, Jonas, Sun, Jing, Li, Xue, Burgess, Stephen, Michaëlsson, Karl
Publicado 2023

Advanced Age in Humans and Mouse Models of Glioblastoma Show Decreased Survival from Extratumoral Influence

por Johnson, Margaret, Bell, April, Lauing, Kristen L., Ladomersky, Erik, Zhai, Lijie, Penco-Campillo, Manon, Shah, Yajas, Mauer, Elizabeth, Xiu, Joanne, Nicolaides, Theodore, Drumm, Michael, McCortney, Kathleen, Elemento, Olivier, Kim, Miri, Bommi, Prashant, Low, Justin T., Memon, Ruba, Wu, Jennifer, Zhao, Junfei, Mi, Xinlei, Glantz, Michael J., Sengupta, Soma, Castro, Brandyn, Yamini, Bakhtiar, Horbinski, Craig, Baker, Darren J., Walunas, Theresa L., Schiltz, Gary E., Lukas, Rimas V., Wainwright, Derek A.
Publicado 2023

Clinical Behavior and Molecular Landscape of Stage I p53-Abnormal Low-Grade Endometrioid Endometrial Carcinomas

por Jamieson, Amy, Vermij, Lisa, Kramer, Claire J.H., Jobsen, Jan J., Jürgemlienk-Schulz, Ina, Lutgens, Ludy, Mens, Jan Willem, Haverkort, Marie A.D., Slot, Annerie, Nout, Remi A., Oosting, Jan, Carlson, Joseph, Howitt, Brooke E., Ip, Philip P.C., Lax, Sigurd F., McCluggage, W. Glenn, Singh, Naveena, McAlpine, Jessica N., Creutzberg, Carien L., Horeweg, Nanda, Gilks, C. Blake, Bosse, Tjalling
Publicado 2023