Mapping the Lay of the Land: Using Interactive Network Analytic Tools for Collaboration in Rural Cancer Prevention and Control

por Carothers, Bobbi J., Allen, Peg, Walsh-Bailey, Callie, Duncan, Dixie, Pacheco, Rebeca Vanderburg, White, Karen R., Jeckstadt, Debra, Tsai, Edward, Brownson, Ross C.
Publicado 2022

Immune Mechanisms of Resistance to Cediranib in Ovarian Cancer

por Gopinathan, Ganga, Berlato, Chiara, Lakhani, Anissa, Szabova, Ludmila, Pegrum, Colin, Pedrosa, Ana-Rita, Laforets, Florian, Maniati, Eleni, Balkwill, Frances R.
Publicado 2022

The Spatial Landscape of Progression and Immunoediting in Primary Melanoma at Single-Cell Resolution

por Nirmal, Ajit J., Maliga, Zoltan, Vallius, Tuulia, Quattrochi, Brian, Chen, Alyce A., Jacobson, Connor A., Pelletier, Roxanne J., Yapp, Clarence, Arias-Camison, Raquel, Chen, Yu-An, Lian, Christine G., Murphy, George F., Santagata, Sandro, Sorger, Peter K.
Publicado 2022

Identification and Management of Pathogenic Variants in BRCA1, BRCA2, and PALB2 in a Tumor-Only Genomic Testing Program

por Bychkovsky, Brittany L., Li, Tianyu, Sotelo, Jilliane, Tayob, Nabihah, Mercado, Joanna, Gomy, Israel, Chittenden, Anu, Kane, Sarah, Stokes, Samantha, Hughes, Melissa E., Kim, Ji Seok, Umeton, Renato, Awad, Mark M., Konstantinopoulos, Panagiotis A., Yurgelun, Matthew B., Wolpin, Brian M., Taplin, Mary-Ellen, Newmark, Randall E., Johnson, Bruce E., Lindeman, Neal I., MacConaill, Laura E., Garber, Judy E., Lin, Nancy U.
Publicado 2022

The Genomics of Colorectal Cancer in Populations with African and European Ancestry

por Myer, Parvathi A., Lee, Jessica K., Madison, Russell W., Pradhan, Kith, Newberg, Justin Y., Isasi, Carmen R., Klempner, Samuel J., Frampton, Garrett M., Ross, Jeffery S., Venstrom, Jeffrey M., Schrock, Alexa B., Das, Sudipto, Augenlicht, Leonard, Verma, Amit, Greally, John M., Raj, Srilakshmi M., Goel, Sanjay, Ali, Siraj M.
Publicado 2022

The Improving Risk Informed HPV Screening (IRIS) Study: Design and Baseline Characteristics

por Gage, Julia C., Raine-Bennett, Tina, Schiffman, Mark, Clarke, Megan A., Cheung, Li C., Poitras, Nancy E., Varnado, Nicole E., Katki, Hormuzd A., Castle, Philip E., Befano, Brian, Chandra, Malini, Rydzak, Greg, Lorey, Thomas, Wentzensen, Nicolas
Publicado 2022

Immune Determinants of the Association between Tumor Mutational Burden and Immunotherapy Response across Cancer Types

por Sinha, Neelam, Sinha, Sanju, Valero, Cristina, Schäffer, Alejandro A., Aldape, Kenneth, Litchfield, Kevin, Chan, Timothy A., Morris, Luc G.T., Ruppin, Eytan
Publicado 2022

Phosphorylation of SHP2 at Tyr62 Enables Acquired Resistance to SHP2 Allosteric Inhibitors in FLT3-ITD–Driven AML

por Pfeiffer, Anamarija, Franciosa, Giulia, Locard-Paulet, Marie, Piga, Ilaria, Reckzeh, Kristian, Vemulapalli, Vidyasiri, Blacklow, Stephen C., Theilgaard-Mönch, Kim, Jensen, Lars J., Olsen, Jesper V.
Publicado 2022

Epigenetic and Transcriptional Regulation of Innate Immunity in Cancer

por Chen, Chuan, Man, Na, Liu, Fan, Martin, Gloria Mas, Itonaga, Hidehiro, Sun, Jun, Nimer, Stephen D.
Publicado 2022

Insights into Immune Escape During Tumor Evolution and Response to Immunotherapy Using a Rat Model of Breast Cancer

por Gil Del Alcazar, Carlos R., Trinh, Anne, Alečković, Maša, Rojas Jimenez, Ernesto, Harper, Nicholas W., Oliphant, Michael U.J., Xie, Shanshan, Krop, Ethan D., Lulseged, Bethlehem, Murphy, Katherine C., Keenan, Tanya E., Van Allen, Eliezer M., Tolaney, Sara M., Freeman, Gordon J., Dillon, Deborah A., Muthuswamy, Senthil K., Polyak, Kornelia
Publicado 2022

A Pan-Cancer Immunogenomic Atlas for Immune Checkpoint Blockade Immunotherapy

por Yang, Jing, Zhao, Shilin, Wang, Jing, Sheng, Quanhu, Liu, Qi, Shyr, Yu
Publicado 2022

Selective Vulnerability of Senescent Glioblastoma Cells to BCL-XL Inhibition

por Rahman, Masum, Olson, Ian, Mansour, Moustafa, Carlstrom, Lucas P., Sutiwisesak, Rujapope, Saber, Rehan, Rajani, Karishma, Warrington, Arthur E., Howard, Adam, Schroeder, Mark, Chen, Sisi, Decker, Paul A., Sananikone, Eliot F., Zhu, Yi, Tchkonia, Tamar, Parney, Ian F., Burma, Sandeep, Brown, Desmond, Rodriguez, Moses, Sarkaria, Jann N., Kirkland, James L., Burns, Terry C.
Publicado 2022

ROADMAPS: An Online Database of Response Data, Dosing Regimens, and Toxicities of Approved Oncology Drugs as Single Agents to Guide Preclinical In Vivo Studies

por Hollingshead, Melinda G., Greenberg, Nathaniel, Gottholm-Ahalt, Michelle, Camalier, Richard, Johnson, Barry C., Collins, Jerry M., Doroshow, James H.
Publicado 2022

Modeling Androgen Deprivation Therapy–Induced Prostate Cancer Dormancy and Its Clinical Implications

por Dong, Xin, Xue, Hui, Mo, Fan, Lin, Yen-yi, Lin, Dong, Wong, Nelson K.Y., Sun, Yingqiang, Wilkinson, Scott, Ku, Anson T., Hao, Jun, Ci, Xinpei, Wu, Rebecca, Haegert, Anne, Silver, Rebecca, Taplin, Mary-Ellen, Balk, Steven P., Alumkal, Joshi J., Sowalsky, Adam G., Gleave, Martin, Collins, Colin, Wang, Yuzhuo
Publicado 2022

Transcriptional Reprogramming Differentiates Active from Inactive ESR1 Fusions in Endocrine Therapy-Refractory Metastatic Breast Cancer

por Gou, Xuxu, Anurag, Meenakshi, Lei, Jonathan T., Kim, Beom-Jun, Singh, Purba, Seker, Sinem, Fandino, Diana, Han, Airi, Rehman, Saif, Hu, Jianhong, Korchina, Viktoriya, Doddapaneni, Harshavardhan, Dobrolecki, Lacey E., Mitsiades, Nicholas, Lewis, Michael T., Welm, Alana L., Li, Shunqiang, Lee, Adrian V., Robinson, Dan R., Foulds, Charles E., Ellis, Matthew J.
Publicado 2021

Combinatorial Natural Killer Cell–based Immunotherapy Approaches Selectively Target Chordoma Cancer Stem Cells

por Hoke, Austin T.K., Padget, Michelle R., Fabian, Kellsye P., Nandal, Anjali, Gallia, Gary L., Bilusic, Marijo, Soon-Shiong, Patrick, Hodge, James W., London, Nyall R.
Publicado 2021

Myeloma Genome Project Panel is a Comprehensive Targeted Genomics Panel for Molecular Profiling of Patients with Multiple Myeloma

por Sudha, Parvathi, Ahsan, Aarif, Ashby, Cody, Kausar, Tasneem, Khera, Akhil, Kazeroun, Mohammad H., Hsu, Chih-Chao, Wang, Lin, Fitzsimons, Evelyn, Salminen, Outi, Blaney, Patrick, Czader, Magdalena, Williams, Jonathan, Abu Zaid, Mohammad I., Ansari-Pour, Naser, Yong, Kwee L., van Rhee, Frits, Pierceall, William E., Morgan, Gareth J., Flynt, Erin, Gooding, Sarah, Abonour, Rafat, Ramasamy, Karthik, Thakurta, Anjan, Walker, Brian A.
Publicado 2022

Ultrasmall Nanoparticle Delivery of Doxorubicin Improves Therapeutic Index for High-Grade Glioma

por Aragon-Sanabria, Virginia, Aditya, Anusha, Zhang, Li, Chen, Feng, Yoo, Barney, Cao, Tianye, Madajewski, Brian, Lee, Rachel, Turker, Melik Z., Ma, Kai, Monette, Sebastien, Chen, Peiming, Wu, Jing, Ruan, Shutian, Overholtzer, Michael, Zanzonico, Pat, Rudin, Charles M., Brennan, Cameron, Wiesner, Ulrich, Bradbury, Michelle S.
Publicado 2022

Ribosome Biogenesis: A Central Player in Cancer Metastasis and Therapeutic Resistance

por Elhamamsy, Amr R., Metge, Brandon J., Alsheikh, Heba A., Shevde, Lalita A., Samant, Rajeev S.
Publicado 2022

Development of Highly Effective Anti-Mesothelin hYP218 Chimeric Antigen Receptor T Cells With Increased Tumor Infiltration and Persistence for Treating Solid Tumors

por Tomar, Sakshi, Zhang, Jingli, Khanal, Manakamana, Hong, Jessica, Venugopalan, Abhilash, Jiang, Qun, Sengupta, Manjistha, Miettinen, Markku, Li, Nan, Pastan, Ira, Ho, Mitchell, Hassan, Raffit
Publicado 2022