Extracellular High-Mobility Group Box 1 Acts as an Innate Immune Mediator to Enhance Autoimmune Progression and Diabetes Onset in NOD Mice

por Han, Junyan, Zhong, Jinxin, Wei, Wenzhong, Wang, Ying, Huang, Yafei, Yang, Ping, Purohit, Sharad, Dong, Zheng, Wang, Mong-Heng, She, Jin-Xiong, Gong, Feili, Stern, David M., Wang, Cong-Yi
Publicado 2008

Protein Kinase C-δ Mediates Neuronal Apoptosis in the Retinas of Diabetic Rats via the Akt Signaling Pathway

por Kim, Young-Hee, Kim, Yoon-Sook, Park, Chang-Hwan, Chung, In-Yong, Yoo, Ji-Myong, Kim, Jae-Geun, Lee, Byung-Ju, Kang, Sang-Soo, Cho, Gyeong-Jae, Choi, Wan-Sung
Publicado 2008

Pck1 Gene Silencing in the Liver Improves Glycemia Control, Insulin Sensitivity, and Dyslipidemia in db/db Mice

por Gómez-Valadés, Alicia G., Méndez-Lucas, Andrés, Vidal-Alabró, Anna, Blasco, Francese X., Chillon, Miguel, Bartrons, Ramon, Bermúdez, Jordi, Perales, José C.
Publicado 2008

Association Analysis in African Americans of European-Derived Type 2 Diabetes Single Nucleotide Polymorphisms From Whole-Genome Association Studies

por Lewis, Joshua P., Palmer, Nicholette D., Hicks, Pamela J., Sale, Michele M., Langefeld, Carl D., Freedman, Barry I., Divers, Jasmin, Bowden, Donald W.
Publicado 2008

Obese Mice Lacking Inducible Nitric Oxide Synthase Are Sensitized to the Metabolic Actions of Peroxisome Proliferator–Activated Receptor-γ Agonism

por Dallaire, Patrice, Bellmann, Kerstin, Laplante, Mathieu, Gélinas, Stéphanie, Centeno-Baez, Carolina, Penfornis, Patrice, Peyot, Marie-Line, Latour, Martin G., Lamontagne, Julien, Trujillo, Maria E., Scherer, Philipp E., Prentki, Marc, Deshaies, Yves, Marette, André
Publicado 2008

The Human Lipodystrophy Gene BSCL2/Seipin May Be Essential for Normal Adipocyte Differentiation

por Payne, Victoria A., Grimsey, Neil, Tuthill, Antoinette, Virtue, Sam, Gray, Sarah L., Nora, Edoardo Dalla, Semple, Robert K., O'Rahilly, Stephen, Rochford, Justin J.
Publicado 2008

Selective Small-Molecule Agonists of G Protein–Coupled Receptor 40 Promote Glucose-Dependent Insulin Secretion and Reduce Blood Glucose in Mice

por Tan, Carina P., Feng, Yue, Zhou, Yun-Ping, Eiermann, George J., Petrov, Aleksandr, Zhou, Changyou, Lin, Songnian, Salituro, Gino, Meinke, Peter, Mosley, Ralph, Akiyama, Taro E., Einstein, Monica, Kumar, Sanjeev, Berger, Joel P., Mills, Sander G., Thornberry, Nancy A., Yang, Lihu, Howard, Andrew D.
Publicado 2008

Autocrine IGF-1 Action in Adipocytes Controls Systemic IGF-1 Concentrations and Growth

por Klöting, Nora, Koch, Linda, Wunderlich, Thomas, Kern, Matthias, Ruschke, Karen, Krone, Wilhelm, Brüning, Jens C., Blüher, Matthias
Publicado 2008

Role of the Transcription Factor Sox4 in Insulin Secretion and Impaired Glucose Tolerance

por Goldsworthy, Michelle, Hugill, Alison, Freeman, Helen, Horner, Emma, Shimomura, Kenju, Bogani, Debora, Pieles, Guido, Mijat, Vesna, Arkell, Ruth, Bhattacharya, Shoumo, Ashcroft, Frances M., Cox, Roger D.
Publicado 2008

Brain Apolipoprotein E: an Important Regulator of Food Intake in Rats

por Shen, Ling, Tso, Patrick, Woods, Stephen C., Clegg, Deborah J., Barber, Kyna L., Carey, Katherine, Liu, Min
Publicado 2008

Angiotensin II Type 1 Receptor Signaling Contributes to Synaptophysin Degradation and Neuronal Dysfunction in the Diabetic Retina

por Kurihara, Toshihide, Ozawa, Yoko, Nagai, Norihiro, Shinoda, Kei, Noda, Kousuke, Imamura, Yutaka, Tsubota, Kazuo, Okano, Hideyuki, Oike, Yuichi, Ishida, Susumu
Publicado 2008

PANIC-ATTAC: A Mouse Model for Inducible and Reversible β-Cell Ablation

por Wang, Zhao V., Mu, James, Schraw, Todd D., Gautron, Laurent, Elmquist, Joel K., Zhang, Bei B., Brownlee, Michael, Scherer, Philipp E.
Publicado 2008

Hypothalamic Protein Kinase C Regulates Glucose Production

por Ross, Rachel, Wang, Penny Y.T., Chari, Madhu, Lam, Carol K.L., Caspi, Liora, Ono, Hiraku, Muse, Evan D., Li, Xiaosong, Gutierrez-Juarez, Roger, Light, Peter E., Schwartz, Gary J., Rossetti, Luciano, Lam, Tony K.T.
Publicado 2008

Activation of Peroxisome Proliferator–Activated Receptor β/δ Inhibits Lipopolysaccharide-Induced Cytokine Production in Adipocytes by Lowering Nuclear Factor-κB Activity via Extrac...

por Rodríguez-Calvo, Ricardo, Serrano, Lucía, Coll, Teresa, Moullan, Norman, Sánchez, Rosa M., Merlos, Manuel, Palomer, Xavier, Laguna, Juan C., Michalik, Liliane, Wahli, Walter, Vázquez-Carrera, Manuel
Publicado 2008

Consequences of Lipid Droplet Coat Protein Downregulation in Liver Cells: Abnormal Lipid Droplet Metabolism and Induction of Insulin Resistance

por Bell, Ming, Wang, Hong, Chen, Hui, McLenithan, John C., Gong, Da-Wei, Yang, Rong-Zee, Yu, Daozhan, Fried, Susan K., Quon, Michael J., Londos, Constantine, Sztalryd, Carole
Publicado 2008

The Common P446L Polymorphism in GCKR Inversely Modulates Fasting Glucose and Triglyceride Levels and Reduces Type 2 Diabetes Risk in the DESIR Prospective General French Populatio...

por Vaxillaire, Martine, Cavalcanti-Proença, Christine, Dechaume, Aurélie, Tichet, Jean, Marre, Michel, Balkau, Beverley, Froguel, Philippe
Publicado 2008

Altered Calcium Homeostasis Does Not Explain the Contractile Deficit of Diabetic Cardiomyopathy

por Zhang, Lin, Cannell, Mark B., Phillips, Anthony R.J., Cooper, Garth J.S., Ward, Marie-Louise
Publicado 2008

Partial Resistance to Peroxisome Proliferator–Activated Receptor-α Agonists in ZDF Rats Is Associated With Defective Hepatic Mitochondrial Metabolism

por Satapati, Santhosh, He, TianTeng, Inagaki, Takeshi, Potthoff, Matthew, Merritt, Matthew E., Esser, Victoria, Mangelsdorf, David J., Kliewer, Steven A., Browning, Jeffrey D., Burgess, Shawn C.
Publicado 2008

Impact of Disease Management on Utilization and Adherence With Drugs and Tests: The case of diabetes treatment in the Florida: A Healthy State (FAHS) program

por Thiebaud, Patrick, Demand, Michael, Wolf, Scott A., Alipuria, Linda L., Ye, Qin, Gutierrez, Peter R.
Publicado 2008

Two-Year Pulmonary Safety and Efficacy of Inhaled Human Insulin (Exubera) in Adult Patients With Type 2 Diabetes

por Rosenstock, Julio, Cefalu, William T., Hollander, Priscilla A., Belanger, Andre, Eliaschewitz, Freddy G., Gross, Jorge L., Klioze, Solomon S., St. Aubin, Lisa B., Foyt, Howard, Ogawa, Masayo, Duggan, William T.
Publicado 2008