Neural stemness unifies cell tumorigenicity and pluripotent differentiation potential

por Zhang, Min, Liu, Yang, Shi, Lihua, Fang, Lei, Xu, Liyang, Cao, Ying
Publicado 2022

Withdrawal: Mitochondrial pyruvate carrier blockade results in decreased osteoclastogenesis and bone resorption via regulating mitochondrial energy production

por Guo, Qian, Zhao, Hongjian, Cheng, Haozhe, Kang, Honglei, Dong, Yimin, Peng, Renpeng, Zhu, Meipeng, Fang, Zhong, Li, Feng
Publicado 2022

3D cryo-EM imaging of bacterial flagella: Novel structural and mechanistic insights into cell motility

por Mondino, Sonia, San Martin, Fabiana, Buschiazzo, Alejandro
Publicado 2022

Suppressor mutations in Escherichia coli RNA polymerase alter transcription initiation but do not affect translesion RNA synthesis in vitro

por Miropolskaya, Nataliya, Petushkov, Ivan, Esyunina, Daria, Kulbachinskiy, Andrey
Publicado 2022

New Views of Old Proteins: Clarifying the Enigmatic Proteome

por Burnum-Johnson, Kristin E., Conrads, Thomas P., Drake, Richard R., Herr, Amy E., Iyengar, Ravi, Kelly, Ryan T., Lundberg, Emma, MacCoss, Michael J., Naba, Alexandra, Nolan, Garry P., Pevzner, Pavel A., Rodland, Karin D., Sechi, Salvatore, Slavov, Nikolai, Spraggins, Jeffrey M., Van Eyk, Jennifer E., Vidal, Marc, Vogel, Christine, Walt, David R., Kelleher, Neil L.
Publicado 2022

Regulation of the lysosome by sphingolipids: Potential role in aging

por Tang, Haiqing, Huang, Xiaokun, Pang, Shanshan
Publicado 2022

Delineation of a minimal topoisomerase II binding protein 1 for regulated activation of ATR at DNA double-strand breaks

por Ruis, Kenna, Huynh, Oanh, Montales, Katrina, Barr, Nina A., Michael, W. Matthew
Publicado 2022

Peroxiredoxin IV plays a critical role in cancer cell growth and radioresistance through the activation of the Akt/GSK3 signaling pathways

por Ding, Na, Jiang, Hong, Thapa, Pratik, Hao, Yanning, Alshahrani, Aziza, Allison, Derek, Izumi, Tadahide, Rangnekar, Vivek M., Liu, Xiaoqi, Wei, Qiou
Publicado 2022

A Spef1-interacting microtubule quartet protein in Trypanosoma brucei promotes flagellar inheritance by regulating basal body segregation

por Pham, Kieu T.M., Zhou, Qing, Lee, Kyu Joon, Li, Ziyin
Publicado 2022

Iron nitrosyl complexes are formed from nitrite in the human placenta

por Mukosera, George T., Principe, Patricia, Mata-Greenwood, Eugenia, Liu, Taiming, Schroeder, Hobe, Parast, Mana, Blood, Arlin B.
Publicado 2022

Adipose-derived exosomes block muscular stem cell proliferation in aged mouse by delivering miRNA Let-7d-3p that targets transcription factor HMGA2

por Itokazu, Maki, Onodera, Yuta, Mori, Tatsufumi, Inoue, Shinji, Yamagishi, Kotaro, Moritake, Akihiro, Iwawaki, Natsumi, Shigi, Kanae, Takehara, Toshiyuki, Higashimoto, Yuji, Akagi, Masao, Teramura, Takeshi
Publicado 2022

miR-134-5p inhibits osteoclastogenesis through a novel miR-134-5p/Itgb1/MAPK pathway

por Huang, Meng, Wang, Yan, Wang, Zhenning, Qin, Qiaozhen, Zhang, Heyang, Liu, Shuirong, Cui, Jiantong, Zhang, Yu, Jiang, Xiaoxia, Xu, Lulu
Publicado 2022

High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP

por Klemm, Bradley P., Sikkema, Andrew P., Hsu, Allen L., Horng, James C., Hall, Traci M. Tanaka, Borgnia, Mario J., Schaaper, Roel M.
Publicado 2022

Distinct functional roles for the M4 α-helix from each homologous subunit in the heteropentameric ligand-gated ion channel nAChR

por Thompson, Mackenzie J., Domville, Jaimee A., Edrington, Claire H., Venes, Angelica, Giguère, Patrick M., Baenziger, John E.
Publicado 2022

Structural and mechanistic insights into the inhibition of type I-F CRISPR-Cas system by anti-CRISPR protein AcrIF23

por Ren, Junhui, Wang, Hao, Yang, Lingguang, Li, Feixue, Wu, Yao, Luo, Zhipu, Chen, Zeliang, Zhang, Yi, Feng, Yue
Publicado 2022

A metal ion–dependent conformational switch modulates activity of the Plasmodium M17 aminopeptidase

por Webb, Chaille T., Yang, Wei, Riley, Blake T., Hayes, Brooke K., Sivaraman, Komagal Kannan, Malcolm, Tess R., Harrop, Stephen, Atkinson, Sarah C., Kass, Itamar, Buckle, Ashley M., Drinkwater, Nyssa, McGowan, Sheena
Publicado 2022

Plasminogen and plasmin can bind to human T cells and generate truncated CCL21 that increases dendritic cell chemotactic responses

por Loef, Evert J., Sheppard, Hilary M., Birch, Nigel P., Dunbar, P. Rod
Publicado 2022

Tumor protein D54 binds intracellular nanovesicles via an extended amphipathic region

por Reynaud, Antoine, Magdeleine, Maud, Patel, Amanda, Gay, Anne-Sophie, Debayle, Delphine, Abelanet, Sophie, Antonny, Bruno
Publicado 2022

A multi-omics analysis reveals that the lysine deacetylase ABHD14B influences glucose metabolism in mammals

por Rajendran, Abinaya, Soory, Amarendranath, Khandelwal, Neha, Ratnaparkhi, Girish, Kamat, Siddhesh S.
Publicado 2022

Elesclomol elevates cellular and mitochondrial iron levels by delivering copper to the iron import machinery

por Garza, Natalie M., Zulkifli, Mohammad, Gohil, Vishal M.
Publicado 2022