Competitive inhibition of the classical complement pathway using exogenous single-chain C1q recognition proteins

por Vadászi, Henrietta, Kiss, Bence, Micsonai, András, Schlosser, Gitta, Szaniszló, Tamás, Kovács, Réka Á., Györffy, Balázs A., Kékesi, Katalin A., Goto, Yuji, Uzonyi, Barbara, Liliom, Károly, Kardos, József
Publicado 2022

Oxidative stress activates transcription of Salmonella pathogenicity island-2 genes in macrophages

por Kim, Ju-Sim, Liu, Lin, Davenport, Bennett, Kant, Sashi, Morrison, Thomas E., Vazquez-Torres, Andres
Publicado 2022

ANGPTL4 silencing via antisense oligonucleotides reduces plasma triglycerides and glucose in mice without causing lymphadenopathy

por Deng, Mingjuan, Kutrolli, Elda, Sadewasser, Anne, Michel, Sven, Joibari, Masoumeh Motamedi, Jaschinski, Frank, Olivecrona, Gunilla, Nilsson, Stefan K., Kersten, Sander
Publicado 2022

A novel antiproliferative PKCα-Ras-ERK signaling axis in intestinal epithelial cells

por Kaur, Navneet, Lum, Michelle A., Lewis, Robert E., Black, Adrian R., Black, Jennifer D.
Publicado 2022

Crystal structure of the Rubella virus protease reveals a unique papain-like protease fold

por Cheong, Ezekiel Ze Ken, Quek, Jun Ping, Xin, Liu, Li, Chaoqiang, Chan, Jing Yi, Liew, Chong Wai, Mu, Yuguang, Zheng, Jie, Luo, Dahai
Publicado 2022

Recognition of 3′ nucleotide context and stop codon readthrough are determined during mRNA translation elongation

por Biziaev, Nikita, Sokolova, Elizaveta, Yanvarev, Dmitry V., Toropygin, Ilya Yu, Shuvalov, Alexey, Egorova, Tatiana, Alkalaeva, Elena
Publicado 2022

Identification and characterization of 3-ketosphinganine reductase activity encoded at the BT_0972 locus in Bacteroides thetaiotaomicron

por Lee, Min-Ting, Le, Henry H., Besler, Kevin R., Johnson, Elizabeth L.
Publicado 2022

The neurosteroid pregnenolone is synthesized by a mitochondrial P450 enzyme other than CYP11A1 in human glial cells

por Lin, Yiqi Christina, Cheung, Garett, Porter, Edith, Papadopoulos, Vassilios
Publicado 2022

A biosensor of protein foldedness identifies increased “holdase” activity of chaperones in the nucleus following increased cytosolic protein aggregation

por Raeburn, Candice B., Ormsby, Angelique R., Cox, Dezerae, Gerak, Chloe A., Makhoul, Christian, Moily, Nagaraj S., Ebbinghaus, Simon, Dickson, Alex, McColl, Gawain, Hatters, Danny M.
Publicado 2022

Recent insights into noncanonical 5′ capping and decapping of RNA

por Doamekpor, Selom K., Sharma, Sunny, Kiledjian, Megerditch, Tong, Liang
Publicado 2022

Phosphatidic acid species 34:1 mediates expression of the myo-inositol 3-phosphate synthase gene INO1 for lipid synthesis in yeast

por Gaspar, Maria Laura, Aregullin, Manuel A., Chang, Yu-Fang, Jesch, Stephen A., Henry, Susan A.
Publicado 2022

Characterization of a [4Fe-4S]-dependent LarE sulfur insertase that facilitates nickel-pincer nucleotide cofactor biosynthesis in Thermotoga maritima

por Chatterjee, Shramana, Parson, Kristine F., Ruotolo, Brandon T., McCracken, John, Hu, Jian, Hausinger, Robert P.
Publicado 2022

Coming full circle: On the origin and evolution of the looping model for enhancer–promoter communication

por Popay, Tessa M., Dixon, Jesse R.
Publicado 2022

Self-activating G protein α subunits engage seven-transmembrane regulator of G protein signaling (RGS) proteins and a Rho guanine nucleotide exchange factor effector in the amoeba...

por Bosch, Dustin E., Jeck, William R., Siderovski, David P.
Publicado 2022

10,12-Conjugated linoleic acid supplementation improves HDL composition and function in mice

por Vaisar, Tomas, Wang, Shari, Omer, Mohamed, Irwin, Angela D., Storey, Carl, Tang, Chongren, den Hartigh, Laura J.
Publicado 2022

Histone methyltransferase Dot1L recruits O-GlcNAc transferase to target chromatin sites to regulate histone O-GlcNAcylation

por Xu, Bo, Zhang, Can, Jiang, Ao, Zhang, Xianhong, Liang, Fenfei, Wang, Xueqing, Li, Danni, Liu, Chenglong, Liu, Xiaomei, Xia, Jing, Li, Yang, Wang, Yirong, Yang, Zelan, Chen, Jia, Zhou, Yu, Chen, Liang, Sun, Hui
Publicado 2022

Identification and functional implications of pseudouridine RNA modification on small noncoding RNAs in the mammalian pathogen Trypanosoma brucei

por Rajan, K. Shanmugha, Adler, Katerina, Doniger, Tirza, Cohen-Chalamish, Smadar, Aharon-Hefetz, Noa, Aryal, Saurav, Pilpel, Yitzhak, Tschudi, Christian, Unger, Ron, Michaeli, Shulamit
Publicado 2022

The regulatory role of the Aspergillus flavus core retromer complex in aflatoxin metabolism

por Wang, Sen, Wang, Yu, Liu, Yinghang, Liu, Lin, Li, Jinyu, Yang, Kunlong, Liu, Mengxin, Zeng, Wanlin, Qin, Ling, Lin, Ranxun, Nie, Xinyi, Jiang, Longguang, Wang, Shihua
Publicado 2022

Structure of the second phosphoubiquitin–binding site in parkin

por Fakih, Rayan, Sauvé, Véronique, Gehring, Kalle
Publicado 2022

Identification of a distal enhancer that determines the expression pattern of acute phase marker C-reactive protein

por Wang, Ming-Yu, Zhang, Chun-Miao, Zhou, Hai-Hong, Ge, Zhong-Bo, Su, Chen-Chen, Lou, Zi-Hao, Zhang, Xin-Yun, Xu, Tao-Tao, Li, Si-Yi, Zhu, Li, Zhou, Ya-Li, Wu, Yi, Ji, Shang-Rong
Publicado 2022