GRASP55 regulates the unconventional secretion and aggregation of mutant huntingtin

por Ahat, Erpan, Bui, Sarah, Zhang, Jianchao, da Veiga Leprevost, Felipe, Sharkey, Lisa, Reid, Whitney, Nesvizhskii, Alexey I., Paulson, Henry L., Wang, Yanzhuang
Publicado 2022

Exploring high-resolution chromatin interaction changes and functional enhancers of myogenic marker genes during myogenic differentiation

por Long, Keren, Li, Xiaokai, Su, Duo, Zeng, Sha, Li, Hengkuan, Zhang, Yu, Zhang, Biwei, Yang, Wenying, Li, Penghao, Li, Xuemin, Wang, Xun, Tang, Qianzi, Lu, Lu, Jin, Long, Ma, Jideng, Li, Mingzhou
Publicado 2022

PKCα and PKCδ: Friends and Rivals

por Black, Jennifer D., Affandi, Trisiani, Black, Adrian R., Reyland, Mary E.
Publicado 2022

Polyunsaturated fatty acids promote the rapid fusion of lipid droplets in Caenorhabditis elegans

por Wang, Yanli, Li, Chunxia, Zhang, Jingjing, Xu, Xiumei, Fu, Lin, Xu, Jie, Zhu, Hong, Hu, Ying, Li, Chengbin, Wang, Mengjie, Wu, Yingjie, Zou, Xiaoju, Liang, Bin
Publicado 2022

Development and validation of an isoform-independent monoclonal antibody–based ELISA for measurement of lipoprotein(a)

por Marcovina, Santica M., Navabi, Nazanin, Allen, Serena, Gonen, Ayelet, Witztum, Joseph L., Tsimikas, Sotirios
Publicado 2022

The structural dynamics of full-length divisome transmembrane proteins FtsQ, FtsB, and FtsL in FtsQBL complex formation

por Kong, Wai-Po, Gong, Furong, So, Pui-Kin, Chen, Yu Wai, Chan, Pak-Ho, Leung, Yun-Chung, Wong, Kwok-Yin
Publicado 2022

Sorting through the extensive and confusing roles of sortilin in metabolic disease

por Mitok, Kelly A., Keller, Mark P., Attie, Alan D.
Publicado 2022

A purified energy-converting hydrogenase from Thermoanaerobacter kivui demonstrates coupled H(+)-translocation and reduction in vitro

por Katsyv, Alexander, Müller, Volker
Publicado 2022

A single amino acid residue tunes the stability of the fully reduced flavin cofactor and photorepair activity in photolyases

por Wen, Bin, Xu, Lei, Tang, Yawei, Jiang, Zhen, Ge, Mengting, Liu, Li, Zhu, Guoping
Publicado 2022

A quantitative high-throughput screen identifies compounds that lower expression of the SCA2-and ALS-associated gene ATXN2

por Scoles, Daniel R., Gandelman, Mandi, Paul, Sharan, Dexheimer, Thomas, Dansithong, Warunee, Figueroa, Karla P., Pflieger, Lance T., Redlin, Scott, Kales, Stephen C., Sun, Hongmao, Maloney, David, Damoiseaux, Robert, Henderson, Mark J., Simeonov, Anton, Jadhav, Ajit, Pulst, Stefan M.
Publicado 2022

An acyl-adenylate mimic reveals the structural basis for substrate recognition by the iterative siderophore synthetase DesD

por Yang, Jinping, Banas, Victoria S., Patel, Ketan D., Rivera, Gerry S.M., Mydy, Lisa S., Gulick, Andrew M., Wencewicz, Timothy A.
Publicado 2022

Mechanisms orchestrating the enzymatic activity and cellular functions of deubiquitinases

por Estavoyer, Benjamin, Messmer, Clémence, Echbicheb, Mohamed, Rudd, Christopher E., Milot, Eric, Affar, El Bachir
Publicado 2022

Automating UbiFast for High-throughput and Multiplexed Ubiquitin Enrichment

por Rivera, Keith D., Olive, Meagan E., Bergstrom, Erik J., Nelson, Alissa J., Lee, Kimberly A., Satpathy, Shankha, Carr, Steven A., Udeshi, Namrata D.
Publicado 2021

Uncovering the Depths of the Human Proteome: Antibody-based Technologies for Ultrasensitive Multiplexed Protein Detection and Quantification

por Ren, Annie H., Diamandis, Eleftherios P., Kulasingam, Vathany
Publicado 2021

Pronounced Postmating Response in the Drosophila Female Reproductive Tract Fluid Proteome

por McDonough-Goldstein, Caitlin E., Whittington, Emma, McCullough, Erin L., Buel, Sharleen M., Erdman, Scott, Pitnick, Scott, Dorus, Steve
Publicado 2021

Correction: Schizosaccharomyces pombe Ppr10 and Mpa1 together mediate mitochondrial translational initiation

por Luo, Ying, Wang, Yirong, Huang, Ying
Publicado 2022

Genomic analysis of 1,25-dihydroxyvitamin D(3) action in mouse intestine reveals compartment and segment-specific gene regulatory effects

por Aita, Rohit, Aldea, Dennis, Hassan, Sohaib, Hur, Joseph, Pellon-Cardenas, Oscar, Cohen, Evan, Chen, Lei, Shroyer, Noah, Christakos, Sylvia, Verzi, Michael P., Fleet, James C.
Publicado 2022

β-Cells retain a pool of insulin-containing secretory vesicles regulated by adherens junctions and the cadherin-binding protein p120 catenin

por Dissanayake, Waruni C., Shepherd, Peter R.
Publicado 2022

Crystal structure of Trypanosoma cruzi heme peroxidase and characterization of its substrate specificity and compound I intermediate

por Freeman, Samuel L., Skafar, Vera, Kwon, Hanna, Fielding, Alistair J., Moody, Peter C.E., Martínez, Alejandra, Issoglio, Federico M., Inchausti, Lucas, Smircich, Pablo, Zeida, Ari, Piacenza, Lucía, Radi, Rafael, Raven, Emma L.
Publicado 2022

The p97 segregase cofactor Ubxn7 facilitates replisome disassembly during S-phase

por Tarcan, Zeynep, Poovathumkadavil, Divyasree, Skagia, Aggeliki, Gambus, Agnieszka
Publicado 2022