Induction of zinc finger protein RNF6 auto-ubiquitination for the treatment of myeloma and chronic myeloid leukemia

por Zhuang, Haixia, Ren, Ying, Mao, Chenyu, Zhong, Yueya, Zhang, Zubin, Cao, Biyin, Zhang, Yuming, Huang, Jinqi, Xu, Guoqiang, Huang, Zhenqian, Xu, Yujia, Mao, Xinliang
Publicado 2022

EGF promotes PKM2 O-GlcNAcylation by stimulating O-GlcNAc transferase phosphorylation at Y976 and their subsequent association

por Wang, Yang, Shu, Hengyao, Liu, Jia, Jin, Xin, Wang, Lihua, Qu, Yanzhao, Xia, Mingjie, Peng, Pinghui, Feng, Yunpeng, Wei, Min
Publicado 2022

Contribution of the EssC ATPase to the assembly of the type 7b secretion system in Staphylococcus aureus

por Bobrovskyy, Maksym, Oh, So Young, Missiakas, Dominique
Publicado 2022

Quantitative Acetylomics Reveals Dynamics of Protein Lysine Acetylation in Mouse Livers During Aging and Upon the Treatment of Nicotinamide Mononucleotide

por Li, Jingshu, Cao, Ye, Niu, Kongyan, Qiu, Jiaqian, Wang, Han, You, Yingnan, Li, Dean, Luo, Yu, Zhu, Zhengjiang, Zhang, Yaoyang, Liu, Nan
Publicado 2022

O-GlcNAcylation stabilizes the autophagy-initiating kinase ULK1 by inhibiting chaperone-mediated autophagy upon HPV infection

por Shi, Yingxin, Yan, Sheng, Shao, Guang-Can, Wang, Jinglong, Jian, Yong-Ping, Liu, Bo, Yuan, Yanqiu, Qin, Ke, Nai, Shanshan, Huang, Xiahe, Wang, Yingchun, Chen, Zhenghui, Chen, Xing, Dong, Meng-Qiu, Geng, Yiqun, Xu, Zhi-Xiang, Li, Jing
Publicado 2022

Transcriptional coregulator Ess2 controls survival of post-thymic CD4(+) T cells through the Myc and IL-7 signaling pathways

por Takada, Ichiro, Hidano, Shinya, Takahashi, Sayuri, Yanaka, Kaori, Ogawa, Hidesato, Tsuchiya, Megumi, Yokoyama, Atsushi, Sato, Shingo, Ochi, Hiroki, Nakagawa, Tohru, Kobayashi, Takashi, Nakagawa, Shinichi, Makishima, Makoto
Publicado 2022

Importance of RNA length for in vitro encapsidation by the nucleoprotein of human respiratory syncytial virus

por Gonnin, Lorène, Richard, Charles-Adrien, Gutsche, Irina, Chevret, Didier, Troussier, Joris, Vasseur, Jean-Jacques, Debart, Françoise, Eléouët, Jean-François, Galloux, Marie
Publicado 2022

Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans

por Artan, Murat, Hartl, Markus, Chen, Weiqiang, de Bono, Mario
Publicado 2022

Biased GPCR signaling by the native parathyroid hormone–related protein 1 to 141 relative to its N-terminal fragment 1 to 36

por Peña, Karina A., White, Alex D., Savransky, Sofya, Castillo, Ignacio Portales, Jean-Alphonse, Frédéric G., Gardella, Thomas J., Sutkeviciute, Ieva, Vilardaga, Jean-Pierre
Publicado 2022

The ARSACS disease protein sacsin controls lysosomal positioning and reformation by regulating microtubule dynamics

por Francis, Vincent, Alshafie, Walaa, Kumar, Rahul, Girard, Martine, Brais, Bernard, McPherson, Peter S.
Publicado 2022

Maternal high-cholesterol diet negatively programs offspring bone development and downregulates hedgehog signaling in osteoblasts

por Mangu, SVVS Ravi, Patel, Kalpana, Sukhdeo, Shinde Vijay, Savitha, M.R., Sharan, Kunal
Publicado 2022

Loss of myeloid lipoprotein lipase exacerbates adipose tissue fibrosis with collagen VI deposition and hyperlipidemia in leptin-deficient obese mice

por Takahashi, Manabu, Yamamuro, Daisuke, Wakabayashi, Tetsuji, Takei, Akihito, Takei, Shoko, Nagashima, Shuichi, Okazaki, Hiroaki, Ebihara, Ken, Yagyu, Hiroaki, Takayanagi, Yuki, Onaka, Tatsushi, Goldberg, Ira J., Ishibashi, Shun
Publicado 2022

An intrinsically disordered transcription activation domain increases the DNA binding affinity and reduces the specificity of NFκB p50/RelA

por Baughman, Hannah E.R., Narang, Dominic, Chen, Wei, Villagrán Suárez, Amalia C., Lee, Joan, Bachochin, Maxwell J., Gunther, Tristan R., Wolynes, Peter G., Komives, Elizabeth A.
Publicado 2022

Ubiquitin-specific protease TRE17/USP6 promotes tumor cell invasion through the regulation of glycoprotein CD147 intracellular trafficking

por Ogura, Yukino, Ohbayashi, Norihiko, Kanaho, Yasunori, Kawaguchi, Atsushi, Funakoshi, Yuji
Publicado 2022

Homeodomain-interacting protein kinase HIPK4 regulates phosphorylation of manchette protein RIMBP3 during spermiogenesis

por Liu, Xiaofei, Zang, Chunyan, Wu, Yifei, Meng, Ru, Chen, Yu, Jiang, Tao, Wang, Cheng, Yang, Xiaoyu, Guo, Yueshuai, Situ, Chenghao, Hu, Zhibin, Zhang, Jun, Guo, Xuejiang
Publicado 2022

Interactions between mTORC2 core subunits Rictor and mSin1 dictate selective and context-dependent phosphorylation of substrate kinases SGK1 and Akt

por Yu, Zanlin, Chen, Junliang, Takagi, Enzo, Wang, Feng, Saha, Bidisha, Liu, Xi, Joubert, Lydia-Marie, Gleason, Catherine E., Jin, Mingliang, Li, Chengmin, Nowotny, Carlos, Agard, David, Cheng, Yifan, Pearce, David
Publicado 2022

The secondary pocket of cryptochrome 2 is important for the regulation of its stability and localization

por Parlak, Gizem Cagla, Camur, Bilge Bahar, Gul, Seref, Ozcan, Onur, Baris, Ibrahim, Kavakli, Ibrahim Halil
Publicado 2022

Extracellular loop 2 of G protein–coupled olfactory receptors is critical for odorant recognition

por Yu, Yiqun, Ma, Zhenjie, Pacalon, Jody, Xu, Lun, Li, Weihao, Belloir, Christine, Topin, Jeremie, Briand, Loïc, Golebiowski, Jérôme, Cong, Xiaojing
Publicado 2022

Two types of peptides derived from the neurotoxin GsMTx4 inhibit a mechanosensitive potassium channel by modifying the mechanogate

por Zhou, Nan, Li, Hui, Xu, Jie, Shen, Zhong-Shan, Tang, Mingxi, Wang, Xiao-Hui, Su, Wan-Xin, Sokabe, Masahiro, Zhang, Zhe, Tang, Qiong-Yao
Publicado 2022

Chlamydia trachomatis development requires both host glycolysis and oxidative phosphorylation but has only minor effects on these pathways

por N’Gadjaga, Maimouna D., Perrinet, Stéphanie, Connor, Michael G., Bertolin, Giulia, Millot, Gaël A., Subtil, Agathe
Publicado 2022