Alkaline pH has an unexpected effect on transcriptional pausing during synthesis of the Escherichia coli pH-responsive riboswitch

por Stephen, Christine, Mishanina, Tatiana V.
Publicado 2022

Human CIDEC transgene improves lipid metabolism and protects against high-fat diet–induced glucose intolerance in mice

por Gupta, Abhishek, Balakrishnan, Bijinu, Karki, Shakun, Slayton, Mark, Jash, Sukanta, Banerjee, Sayani, Grahn, Tan Hooi Min, Jambunathan, Srikarthika, Disney, Sarah, Hussein, Hebaallaha, Kong, Dong, Lowell, Bradford B., Natarajan, Purushothaman, Reddy, Umesh K., Gokce, Noyan, Sharma, Vishva M., Puri, Vishwajeet
Publicado 2022

GOLM1 depletion modifies cellular sphingolipid metabolism and adversely affects cell growth

por Nagaraj, Meghana, Höring, Marcus, Ahonen, Maria A., Nguyen, Van Dien, Zhou, You, Vihinen, Helena, Jokitalo, Eija, Liebisch, Gerhard, Nidhina Haridas, P.A., Olkkonen, Vesa M.
Publicado 2022

Impaired myocellular Ca(2+) cycling in protein phosphatase PP2A-B56α KO mice is normalized by β-adrenergic stimulation

por Glaser, Dennis, Heinick, Alexander, Herting, Julius R., Massing, Fabian, Müller, Frank U., Pauls, Paul, Rozhdestvensky, Timofey S., Schulte, Jan S., Seidl, Matthias D., Skryabin, Boris V., Stümpel, Frank, Kirchhefer, Uwe
Publicado 2022

Functional inactivation of Plasmodium falciparum glycogen synthase kinase GSK3 modulates erythrocyte invasion and blocks gametocyte maturation

por Alder, Arne, Wilcke, Louisa, Pietsch, Emma, von Thien, Heidrun, Pazicky, Samuel, Löw, Christian, Mesen-Ramirez, Paolo, Bachmann, Anna, Burda, Paul-Christian, Kunick, Conrad, Sondermann, Holger, Wilson, Danny, Gilberger, Tim-Wolf
Publicado 2022

Phosphatidic acid inhibits inositol synthesis by inducing nuclear translocation of kinase IP6K1 and repression of myo-inositol-3-P synthase

por Lazcano, Pablo, Schmidtke, Michael W., Onu, Chisom J., Greenberg, Miriam L.
Publicado 2022

A novel formamidase is required for riboflavin biosynthesis in invasive bacteria

por Yurgel, Svetlana N., Johnson, Skylar A., Rice, Jennifer, Sa, Na, Bailes, Clayton, Baumgartner, John, Pitzer, Josh E., Roop, R. Martin, Roje, Sanja
Publicado 2022

Placental growth factor stabilizes VEGF receptor-2 protein in retinal pigment epithelial cells by downregulating glycogen synthase kinase 3 activity

por Murata, Miyuki, Noda, Kousuke, Kase, Satoru, Hase, Keitaro, Wu, Di, Ando, Ryo, Ishida, Susumu
Publicado 2022

Identification and characterization of a novel hydroxylamine oxidase, DnfA, that catalyzes the oxidation of hydroxylamine to N(2)

por Wu, Meng-Ru, Miao, Li-Li, Liu, Ying, Qian, Xin-Xin, Hou, Ting-Ting, Ai, Guo-Min, Yu, Lu, Ma, Lan, Gao, Xi-Yan, Qin, Ya-Ling, Zhu, Hai-Zhen, Du, Lei, Li, Sheng-Ying, Tian, Chang-Lin, Li, De-Feng, Liu, Zhi-Pei, Liu, Shuang-Jiang
Publicado 2022

Cellular and molecular characterization of two novel asparagine synthetase gene mutations linked to asparagine synthetase deficiency

por Staklinski, Stephen J., Chang, Mario C., Yu, Fang, Collins Ruff, Kathleen, Franz, David N., Qian, Zhijian, Bloom, Linda B., Merritt, Matthew E., McKenna, Robert, Kilberg, Michael S.
Publicado 2022

Central residues in prion protein PrP(C) are crucial for its conversion into the pathogenic isoform

por Pasiana, Agriani Dini, Miyata, Hironori, Chida, Junji, Hara, Hideyuki, Imamura, Morikazu, Atarashi, Ryuichiro, Sakaguchi, Suehiro
Publicado 2022

Disulfide-crosslink analysis of the ubiquitin ligase Hrd1 complex during endoplasmic reticulum-associated protein degradation

por Pisa, Rudolf, Rapoport, Tom A.
Publicado 2022

Cyclin-dependent kinase-mediated phosphorylation and the negative regulatory domain of transcription factor B-Myb modulate its DNA binding

por Wijeratne, Tilini U., Guiley, Keelan Z., Lee, Hsiau-Wei, Müller, Gerd A., Rubin, Seth M.
Publicado 2022

AMPK-related protein kinase ARK5 regulates subcellular localization of RNA-binding protein hnRNP A1 during hypertonic stress

por Bhattarai, Krishna, Richard, Travis, Fatica, Thet, Frangione, Brianna, Willmore, William G., Holcik, Martin
Publicado 2022

Lysine demethylase KDM1A promotes cell growth via FKBP8–BCL2 axis in hepatocellular carcinoma

por Lv, Suli, Zhao, Xuefeng, Zhang, Erlei, Yan, Yingying, Ma, Xianyun, Li, Neng, Zou, Qingli, Sun, Lidong, Song, Tanjing
Publicado 2022

Examination of differential glycoprotein preferences of N-acetylglucosaminyltransferase-IV isozymes a and b

por Osada, Naoko, Nagae, Masamichi, Nakano, Miyako, Hirata, Tetsuya, Kizuka, Yasuhiko
Publicado 2022

Isocitrate dehydrogenase 3b is required for spermiogenesis but dispensable for retinal viability

por Zhu, Siyan, Huang, Jiancheng, Xu, Rong, Wang, Yekai, Wan, Yiming, McNeel, Rachel, Parker, Edward, Kolson, Douglas, Yam, Michelle, Webb, Bradley, Zhao, Chen, Sigado, Jenna, Du, Jianhai
Publicado 2022

The nepenthesin insert in the Plasmodium falciparum aspartic protease plasmepsin V is necessary for enzyme function

por Polino, Alexander J., Miller, Justin J., Bhakat, Soumendranath, Mukherjee, Sumit, Bobba, Suhas, Bowman, Gregory R., Goldberg, Daniel E.
Publicado 2022

Nontraditional translation is the key to UFMylation and beyond

por Lin, Mengjia, Zheng, Xiaoyun, Jin, Jianping
Publicado 2022

Enzymatic dispersion of biofilms: An emerging biocatalytic avenue to combat biofilm-mediated microbial infections

por Ramakrishnan, Reshma, Singh, Ashish Kumar, Singh, Simran, Chakravortty, Dipshikha, Das, Debasis
Publicado 2022