Development of a novel high-throughput screen for the identification of new inhibitors of protein S-acylation

por Salaun, Christine, Takizawa, Hiroya, Galindo, Alex, Munro, Kevin R., McLellan, Jayde, Sugimoto, Isamu, Okino, Tomotaka, Tomkinson, Nicholas C.O., Chamberlain, Luke H.
Publicado 2022

AI protein structure prediction-based modeling and mutagenesis of a protostome receptor and peptide ligands reveal key residues for their interaction

por Guo, Shi-Qi, Li, Ya-Dong, Chen, Ping, Zhang, Guo, Wang, Hui-Ying, Jiang, Hui-Min, Liu, Wei-Jia, Xu, Ju-Ping, Ding, Xue-Ying, Fu, Ping, Yu, Ke, Zhou, Hai-Bo, Checco, James W., Jing, Jian
Publicado 2022

Spatial Proteomics Reveals Differences in the Cellular Architecture of Antibody-Producing CHO and Plasma Cell–Derived Cells

por Kretz, Robin, Walter, Larissa, Raab, Nadja, Zeh, Nikolas, Gauges, Ralph, Otte, Kerstin, Fischer, Simon, Stoll, Dieter
Publicado 2022

Tissue-Characteristic Expression of Mouse Proteome

por Lu, Tian, Qian, Liujia, Xie, Yuting, Zhang, Qiushi, Liu, Wei, Ge, Weigang, Zhu, Yi, Ma, Lijia, Zhang, Cheng, Guo, Tiannan
Publicado 2022

Mass Spectrometry and Machine Learning Reveal Determinants of Client Recognition by Antiamyloid Chaperones

por Österlund, Nicklas, Vosselman, Thibault, Leppert, Axel, Gräslund, Astrid, Jörnvall, Hans, Ilag, Leopold L., Marklund, Erik G., Elofsson, Arne, Johansson, Jan, Sahin, Cagla, Landreh, Michael
Publicado 2022

2022 Herbert Tabor Early Career Investigator Awards: Call for nominations

por Farabaugh, Kenneth T., Toker, Alex, DeMartino, George
Publicado 2022

New insights into P2X7 receptor regulation: Ca(2+)-calmodulin and GDP bind to the soluble P2X7 ballast domain

por Sander, Simon, Müller, Isabel, Garcia-Alai, Maria M., Nicke, Annette, Tidow, Henning
Publicado 2022

Still rocking in the structural era: A molecular overview of the small multidrug resistance (SMR) transporter family

por Burata, Olive E., Yeh, Trevor Justin, Macdonald, Christian B., Stockbridge, Randy B.
Publicado 2022

Chloroplast envelope ATPase PGA1/AtFtsH12 is required for chloroplast protein accumulation and cytosol-chloroplast protein homeostasis in Arabidopsis

por Li, Qinglong, Wang, Xiaomin, Lei, Yang, Wang, Yanling, Li, Bilang, Liu, Xiayan, An, Lijun, Yu, Fei, Qi, Yafei
Publicado 2022

Structural variations and roles of rhamnose-rich cell wall polysaccharides in Gram-positive bacteria

por Guérin, Hugo, Kulakauskas, Saulius, Chapot-Chartier, Marie-Pierre
Publicado 2022

The atypical Rab GTPase associated with Parkinson’s disease, Rab29, is localized to membranes

por Nagai-Ito, Yuki, Xu, Lejia, Ito, Kyohei, Kajihara, Yotaro, Ito, Genta, Tomita, Taisuke
Publicado 2022

Evolution and molecular basis of substrate specificity in a 3-ketoacyl-CoA synthase gene cluster from Populus trichocarpa

por Chen, Jeff Y., Mumtaz, Arishba, Gonzales-Vigil, Eliana
Publicado 2022

Elucidation of the interaction proteome of mitochondrial chaperone Hsp78 highlights its role in protein aggregation during heat stress

por Jaworek, Witold, Sylvester, Marc, Cenini, Giovanna, Voos, Wolfgang
Publicado 2022

A STUB1 ubiquitin ligase/CHIC2 protein complex negatively regulates the IL-3, IL-5, and GM-CSF cytokine receptor common β chain (CSF2RB) protein stability

por Koochaki, Sebastian H.J., Słabicki, Mikołaj, Lumpkin, Ryan, Zou, Charles, Belizaire, Roger, Fischer, Eric S., Ebert, Benjamin L.
Publicado 2022

Estradiol production of granulosa cells is unaffected by the physiological mix of nonesterified fatty acids in follicular fluid

por Baddela, Vijay Simha, Michaelis, Marten, Sharma, Arpna, Plinski, Christian, Viergutz, Torsten, Vanselow, Jens
Publicado 2022

Outer membrane vesicles as molecular biomarkers for Gram-negative sepsis: Taking advantage of nature’s perfect packages

por Michel, Lea Vacca, Gaborski, Thomas
Publicado 2022

Using T4 genetics and Laemmli’s development of high-resolution SDS gel electrophoresis to reveal structural protein interactions controlling protein folding and phage self-assembly...

por King, Jonathan
Publicado 2022

Microarray-guided evaluation of the frequency, B-cell origins, and selectivity of human glycan-binding antibodies reveals new insights and novel antibodies

por Temme, J. Sebastian, Crainic, Jennifer A., Walker, Laura M., Yang, Weizhun, Tan, Zibin, Huang, Xuefei, Gildersleeve, Jeffrey C.
Publicado 2022

The SET-domain protein CgSet4 negatively regulates antifungal drug resistance via the ergosterol biosynthesis transcriptional regulator CgUpc2a

por Bhakt, Priyanka, Raney, Mayur, Kaur, Rupinder
Publicado 2022

Coprinopsis cinerea dioxygenase is an oxygenase forming 10(S)-hydroperoxide of linoleic acid, essential for mushroom alcohol, 1-octen-3-ol, synthesis

por Teshima, Takuya, Funai, Risa, Nakazawa, Takehito, Ito, Junya, Utsumi, Toshihiko, Kakumyan, Pattana, Mukai, Hiromi, Yoshiga, Toyoshi, Murakami, Ryutaro, Nakagawa, Kiyotaka, Honda, Yoichi, Matsui, Kenji
Publicado 2022