Correction: Sj7170, a unique dual-function peptide with a specific α-chymotrypsin inhibitory activity and a potent tumor-activating effect from scorpion venom

por Song, Yu, Gong, Ke, Yan, Hong, Hong, Wei, Wang, Le, Wu, Yingliang, Li, Wenhua, Li, Wenxin, Cao, Zhijian
Publicado 2022

Intermittent hypoxia enhances the expression of hypoxia inducible factor HIF1A through histone demethylation

por Martinez, Chloe-Anne, Jiramongkol, Yannasittha, Bal, Neha, Alwis, Imala, Nedoboy, Polina E., Farnham, Melissa M.J., White, Mark D., Cistulli, Peter A., Cook, Kristina M.
Publicado 2022

Transmembrane serine protease TMPRSS2 implicated in SARS-CoV-2 infection is autoactivated intracellularly and requires N-glycosylation for regulation

por Zhang, Yikai, Sun, Shijin, Du, Chunyu, Hu, Kaixuan, Zhang, Ce, Liu, Meng, Wu, Qingyu, Dong, Ningzheng
Publicado 2022

The major trimeric antenna complexes serve as a site for qH-energy dissipation in plants

por Bru, Pierrick, Steen, Collin J., Park, Soomin, Amstutz, Cynthia L., Sylak-Glassman, Emily J., Lam, Lam, Fekete, Agnes, Mueller, Martin J., Longoni, Fiamma, Fleming, Graham R., Niyogi, Krishna K., Malnoë, Alizée
Publicado 2022

The staphylococcal inhibitory protein SPIN binds to human myeloperoxidase with picomolar affinity but only dampens halide oxidation

por Leitgeb, Urban, Furtmüller, Paul G., Hofbauer, Stefan, Brito, Jose A., Obinger, Christian, Pfanzagl, Vera
Publicado 2022

Blocking Lipid Uptake Pathways Does not Prevent Toxicity in Adipose Triglyceride Lipase (ATGL) Deficiency

por Oluwadare, Jide, Cabodevilla, Ainara G., Son, Ni-Huiping, Hu, Yunying, Mullick, Adam E., Verano, Michael, Alemán, Jose O., Ramasamy, Ravichandran, Goldberg, Ira J.
Publicado 2022

Lactation alters the relationship between liver lipid synthesis and hepatic fat stores in the postpartum period

por Ramos-Roman, Maria A., Syed-Abdul, Majid M., Casey, Brian M., Alger, Jeffry R., Liu, Yu-Lun, Parks, Elizabeth J.
Publicado 2022

Elevated n-3/n-6 PUFA ratio in early life diet reverses adverse intrauterine kidney programming in female rats

por Voggel, Jenny, Fink, Gregor, Zelck, Magdalena, Wohlfarth, Maria, Post, Julia M., Bindila, Laura, Rauh, Manfred, Amann, Kerstin, Alejandre Alcázar, Miguel A., Dötsch, Jörg, Nüsken, Kai-Dietrich, Nüsken, Eva
Publicado 2022

Eisosome protein Pil1 regulates mitochondrial morphology, mitophagy, and cell death in Saccharomyces cerevisiae

por Pal, Amita, Paripati, Arun Kumar, Deolal, Pallavi, Chatterjee, Arpan, Prasad, Pushpa Rani, Adla, Priyanka, Sepuri, Naresh Babu V.
Publicado 2022

m6A RNA methylation regulates the transcription factors JUN and JUNB in TGF-β-induced epithelial–mesenchymal transition of lung cancer cells

por Suphakhong, Kusuma, Terashima, Minoru, Wanna-udom, Sasithorn, Takatsuka, Risa, Ishimura, Akihiko, Takino, Takahisa, Suzuki, Takeshi
Publicado 2022

Biochemical and structural basis for the pharmacological inhibition of nuclear hormone receptor PPARγ by inverse agonists

por Irwin, Sean, Karr, Craig, Furman, Craig, Tsai, Jennifer, Gee, Patricia, Banka, Deepti, Wibowo, Ardian S., Dementiev, Alexey A., O’Shea, Morgan, Yang, Joyce, Lowe, Jason, Mitchell, Lorna, Ruppel, Sabine, Fekkes, Peter, Zhu, Ping, Korpal, Manav, Larsen, Nicholas A.
Publicado 2022

The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/insulin-like growth factor receptor signaling

por Gayen, Manoshi, Benoit, Marc R., Fan, Qingyuan, Hudobenko, Jacob, Yan, Riqiang
Publicado 2022

Dissipation of the proton electrochemical gradient in chloroplasts promotes the oxidation of ATP synthase by thioredoxin-like proteins

por Sekiguchi, Takatoshi, Yoshida, Keisuke, Wakabayashi, Ken-Ichi, Hisabori, Toru
Publicado 2022

Enhanced membrane binding of oncogenic G protein αqQ209L confers resistance to inhibitor YM-254890

por Randolph, Clinita E., Dwyer, Morgan B., Aumiller, Jenna L., Dixon, Alethia J., Inoue, Asuka, Osei-Owusu, Patrick, Wedegaertner, Philip B.
Publicado 2022

Elucidation of the substrate of tRNA-modifying enzymes MnmEG leads to in vitro reconstitution of an evolutionarily conserved uridine hypermodification

por Bommisetti, Praneeth, Young, Anthony, Bandarian, Vahe
Publicado 2022

Ancestral archaea expanded the genetic code with pyrrolysine

por Guo, Li-Tao, Amikura, Kazuaki, Jiang, Han-Kai, Mukai, Takahito, Fu, Xian, Wang, Yane-Shih, O’Donoghue, Patrick, Söll, Dieter, Tharp, Jeffery M.
Publicado 2022

Mutations of Rad6 E2 ubiquitin-conjugating enzymes at alanine-126 in helix-3 affect ubiquitination activity and decrease enzyme stability

por Shukla, Prakash K., Sinha, Dhiraj, Leng, Andrew M., Bissell, Jesse E., Thatipamula, Shravya, Ganguly, Rajarshi, Radmall, Kaitlin S., Skalicky, Jack J., Shrieve, Dennis C., Chandrasekharan, Mahesh B.
Publicado 2022

A New Monoclonal Antibody Enables BAR Analysis of Subcellular Importin β1 Interactomes

por Song, Didi-Andreas, Alber, Stefanie, Doron-Mandel, Ella, Schmid, Vera, Albus, Christin A., Leitner, Orith, Hamawi, Hedva, Oses-Prieto, Juan A., Dezorella, Nili, Burlingame, Alma L., Fainzilber, Mike, Rishal, Ida
Publicado 2022

Using reporters of different misfolded proteins reveals differential strategies in processing protein aggregates

por Schneider, Kara L., Ahmadpour, Doryaneh, Keuenhof, Katharina S., Eisele-Bürger, Anna Maria, Berglund, Lisa Larsson, Eisele, Frederik, Babazadeh, Roja, Höög, Johanna L., Nyström, Thomas, Widlund, Per O.
Publicado 2022

MqsR is a noncanonical microbial RNase toxin that is inhibited by antitoxin MqsA via steric blockage of substrate binding

por Yu, Victor, Ronzone, Erik, Lord, Dana, Peti, Wolfgang, Page, Rebecca
Publicado 2022