Molecular characterization of the type VI secretion system effector Tlde1a reveals a structurally altered LD-transpeptidase fold

por Lorente Cobo, Neil, Sibinelli-Sousa, Stephanie, Biboy, Jacob, Vollmer, Waldemar, Bayer-Santos, Ethel, Prehna, Gerd
Publicado 2022

Hepatic Deletion of X-Box Binding Protein 1 in FXR Null Mice Leads to Enhanced Liver Injury

por Liu, Xiaoying, Khalafalla, Mahmoud, Chung, Chuhan, Gindin, Yevgeniy, Hubchak, Susan, LeCuyer, Brian, Kriegermeier, Alyssa, Zhang, Danny, Qiu, Wei, Ding, Xianzhong, Fang, Deyu, Green, Richard
Publicado 2022

Relative Quantification of Proteins in Formalin-Fixed Paraffin-Embedded Breast Cancer Tissue Using Multiplexed Mass Spectrometry Assays

por Steiner, Carine, Lescuyer, Pierre, Cutler, Paul, Tille, Jean-Christophe, Ducret, Axel
Publicado 2022

Natural and engineered inflammasome adapter proteins reveal optimum linker length for self-assembly

por Diaz-Parga, Pedro, Gould, Andrea, de Alba, Eva
Publicado 2022

Plant vernalization proteins contain unusual PHD superdomains without histone H3 binding activity

por Franco-Echevarría, Elsa, Rutherford, Trevor J., Fiedler, Marc, Dean, Caroline, Bienz, Mariann
Publicado 2022

Wnt signaling modulator DKK4 inhibits colorectal cancer metastasis through an AKT/Wnt/β-catenin negative feedback pathway

por Liang, Junrong, Sun, Lina, Li, Yujun, Liu, Wanning, Li, Danxiu, Chen, Ping, Wang, Xin, Hui, Juan, Zhou, Jinchi, Liu, Hao, Cao, Tianyu, Pang, Maogui, Guo, Meng, Wang, Xin, Zhao, Xiaodi, Lu, Yuanyuan
Publicado 2022

Paraspeckle subnuclear bodies depend on dynamic heterodimerisation of DBHS RNA-binding proteins via their structured domains

por Lee, Pei Wen, Marshall, Andrew C., Knott, Gavin J., Kobelke, Simon, Martelotto, Luciano, Cho, Ellie, McMillan, Paul J., Lee, Mihwa, Bond, Charles S., Fox, Archa H.
Publicado 2022

Inner membrane YfgM–PpiD heterodimer acts as a functional unit that associates with the SecY/E/G translocon and promotes protein translocation

por Miyazaki, Ryoji, Ai, Mengting, Tanaka, Natsuko, Suzuki, Takehiro, Dhomae, Naoshi, Tsukazaki, Tomoya, Akiyama, Yoshinori, Mori, Hiroyuki
Publicado 2022

Structural model for ligand binding and channel opening of an insect gustatory receptor

por Morinaga, Satoshi, Nagata, Koji, Ihara, Sayoko, Yumita, Tomohiro, Niimura, Yoshihito, Sato, Koji, Touhara, Kazushige
Publicado 2022

Oxidative stress–induced autonomous activation of the calcium/calmodulin-dependent kinase II involves disulfide formation in the regulatory domain

por Rocco-Machado, Nathália, Lai, Lo, Kim, Geumsoo, He, Yi, Luczak, Elizabeth D., Anderson, Mark E., Levine, Rodney L.
Publicado 2022

Seq’ing the origins of cells in the developing spinal cord

por Rajebhosale, Prithviraj, Talmage, David A.
Publicado 2022

Eicosapentaenoic Acid Ameliorates Cardiac Fibrosis and Tissue Inflammation in Spontaneously Hypertensive Rats

por Gharraee, Nazli, Wang, Zhan, Pflum, Adam, Medina-Hernandez, Danielle, Herrington, David, Zhu, Xuewei, Meléndez, Giselle C.
Publicado 2022

Identification of a Feed-Forward Loop Between 15(S)-HETE and PGE2 in Human Amnion at Parturition

por Zhang, Fan, Sun, Kang, Wang, Wang-Sheng
Publicado 2022

A single-day mouse mesenteric lymph surgery in mice: an updated approach to study dietary lipid absorption, chylomicron secretion, and lymphocyte dynamics

por Dedousis, Nikolaos, Teng, Lihong, Kanshana, Jitendra S., Kohan, Alison B.
Publicado 2022

A Novel, Orally Bioavailable, Small-Molecule Inhibitor of PCSK9 With Significant Cholesterol-Lowering Properties In Vivo

por Suchowerska, Alexandra K., Stokman, Geurt, Palmer, James T., Coghlan, Phillip A., Pieterman, Elsbet J., Keijzer, Nanda, Lambert, Gilles, Chemello, Kevin, Jaafar, Ali K., Parmar, Jasneet, Yan, Liping, Tong, Yingtao, Mu, Lin, Princen, Hans M.G., Bonnar, James, Evison, Benny J.
Publicado 2022

MicroRNA-16 inhibits the TLR4/NF-κB pathway and maintains tight junction integrity in irritable bowel syndrome with diarrhea

por Xi, Meijuan, Zhao, Ping, Li, Fang, Bao, Han, Ding, Sijie, Ji, Lijiang, Yan, Jing
Publicado 2022

Computational and functional studies of the PI(4,5)P(2) binding site of the TRPM3 ion channel reveal interactions with other regulators

por Zhao, Siyuan, Carnevale, Vincenzo, Gabrielle, Matthew, Gianti, Eleonora, Rohacs, Tibor
Publicado 2022

Aging-associated REGγ proteasome decline predisposes to tauopathy

por Tu, Jialu, Zhang, Haiyang, Yang, Ting, Liu, Yun, Kibreab, Solomon, Zhang, Yunpeng, Gao, Liangcai, Moses, Robb E., O'Malley, Bert W., Xiao, Jianru, Li, Xiaotao
Publicado 2022

Cell adhesion molecule CD44v10 promotes stem-like properties in triple-negative breast cancer cells via glucose transporter GLUT1-mediated glycolysis

por Guo, Qian, Qiu, Yaqi, Liu, Yiwen, He, Yiqing, Zhang, Guoliang, Du, Yan, Yang, Cuixia, Gao, Feng
Publicado 2022

The ganglioside GM1a functions as a coreceptor/attachment factor for dengue virus during infection

por Tantirimudalige, Sarala Neomi, Raghuvamsi, Palur Venkata, Sharma, Kamal Kant, Wei Bao, Jonathan Chua, Anand, Ganesh S., Wohland, Thorsten
Publicado 2022