Precise and simultaneous quantification of mitochondrial DNA heteroplasmy and copy number by digital PCR

por Shoop, Wendy K., Gorsuch, Cassandra L., Bacman, Sandra R., Moraes, Carlos T.
Publicado 2022

Transcription suppression is mediated by the HDAC1–Sin3 complex in Xenopus nucleoplasmic extract

por Quaas, Colleen E., Lin, Baicheng, Long, David T.
Publicado 2022

Deciphering Spatial Protein–Protein Interactions in Brain Using Proximity Labeling

por Mathew, Boby, Bathla, Shveta, Williams, Kenneth R., Nairn, Angus C.
Publicado 2022

Probing the sORF-Encoded Peptides of Deinococcus radiodurans in Response to Extreme Stress

por Zhou, Congli, Wang, Qianqian, Huang, Yin, Chen, Zijing, Chen, Shuo, Zhao, Ye, Jia, Chenxi
Publicado 2022

Soluble ANPEP Released From Human Astrocytes as a Positive Regulator of Microglial Activation and Neuroinflammation: Brain Renin–Angiotensin System in Astrocyte–Microglia Crosstalk...

por Kim, Jong-Heon, Afridi, Ruqayya, Cho, Eunji, Yoon, Jong Hyuk, Lim, Yong-Hyun, Lee, Ho-Won, Ryu, Hoon, Suk, Kyoungho
Publicado 2022

Angiotensin II receptor type 1 blockade regulates Klotho expression to induce TSC2-deficient cell death

por Shrestha, Shikshya, Adib, Elio, Imani, Jewel, Aguiar, Dean J., Lamattina, Anthony M., Tassew, Dereje D., Henske, Elizabeth P., Perrella, Mark A., Priolo, Carmen, El-Chemaly, Souheil
Publicado 2022

Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action

por Weinhäupl, Katharina, Gragera, Marcos, Bueno-Carrasco, M. Teresa, Arranz, Rocío, Krandor, Olga, Akopian, Tatos, Soares, Raquel, Rubin, Eric, Felix, Jan, Fraga, Hugo
Publicado 2022

Features and factors that dictate if terminating ribosomes cause or counteract nonsense-mediated mRNA decay

por Embree, Caleb M., Abu-Alhasan, Rabab, Singh, Guramrit
Publicado 2022

A Complex Connection Between the Diversity of Human Gastric Mucin O-Glycans, Helicobacter pylori Binding, Helicobacter Infection and Fucosylation

por Chahal, Gurdeep, Padra, Médea, Erhardsson, Mattias, Jin, Chunsheng, Quintana-Hayashi, Macarena, Venkatakrishnan, Vignesh, Padra, János Tamás, Stenbäck, Helen, Thorell, Anders, Karlsson, Niclas G., Lindén, Sara K.
Publicado 2022

Protein tyrosine kinase 6 regulates activation of SRC kinase

por Alwanian, Wanian M., Vlajic, Katarina, Bie, Wenjun, Kajdacsy-Balla, Andre, Tyner, Angela L.
Publicado 2022

Pentacyclic triterpenes modulate farnesoid X receptor expression in colonic epithelial cells: Implications for colonic secretory function

por Fallon, Ciara M., Smyth, Jessica S., Quach, Andrew, Lajczak-McGinley, Natalia, O’Toole, Aoibhlinn, Barrett, Kim E., Sheridan, Helen, Keely, Stephen J.
Publicado 2022

Channel HCN4 mutation R666Q associated with sporadic arrhythmia decreases channel electrophysiological function and increases protein degradation

por Wang, Hongrui, Wu, Tong, Huang, Zhuo, Huang, Jinghan, Geng, Ze, Cui, Bing, Yan, Yupeng, Zhang, Yu, Wang, Yibo
Publicado 2022

The brain-specific splice variant of the CDC42 GTPase works together with the kinase ACK to downregulate the EGF receptor in promoting neurogenesis

por Endo, Makoto, Cerione, Richard A.
Publicado 2022

Low-dose lithium supplementation promotes adipose tissue browning and sarco(endo)plasmic reticulum Ca(2+) ATPase uncoupling in muscle

por Geromella, Mia S., Ryan, Chantal R., Braun, Jessica L., Finch, Michael S., Maddalena, Lucas A., Bagshaw, Olivia, Hockey, Briana L., Moradi, Fereshteh, Fenech, Rachel K., Ryoo, Jisook, Marko, Daniel M., Dhaliwal, Roopan, Sweezey-Munroe, Jake, Hamstra, Sophie I., Gardner, Georgina, Silvera, Sebastian, Vandenboom, Rene, Roy, Brian D., Stuart, Jeffrey A., MacPherson, Rebecca E.K., Fajardo, Val A.
Publicado 2022

DNA-mediated proteolysis by neutrophil elastase enhances binding activities of the HMGB1 protein

por Wang, Xi, Mayorga-Flores, Marlen, Bien, Karina G., Bailey, Aaron O., Iwahara, Junji
Publicado 2022

Tick-borne encephalitis virus capsid protein induces translational shutoff as revealed by its structural–biological analysis

por Selinger, Martin, Novotný, Radim, Sýs, Jakub, Roby, Justin A., Tykalová, Hana, Ranjani, Ganji Sri, Vancová, Marie, Jaklová, Kateřina, Kaufman, Filip, Bloom, Marshall E., Zdráhal, Zbyněk, Grubhoffer, Libor, Forwood, Jade K., Hrabal, Richard, Rumlová, Michaela, Štěrba, Ján
Publicado 2022

Dietary polyphenols link extracellular histones and nonhistone proteins

por Liu, Jiuyang, Kutateladze, Tatiana G.
Publicado 2022

Deep mutational scanning and massively parallel kinetics of plasminogen activator inhibitor-1 functional stability to probe its latency transition

por Haynes, Laura M., Huttinger, Zachary M., Yee, Andrew, Kretz, Colin A., Siemieniak, David R., Lawrence, Daniel A., Ginsburg, David
Publicado 2022

Ultrahigh resolution MS(1)/MS(2)-based reconstruction of metabolic networks in mammalian cells reveals changes for selenite and arsenite action

por Fan, Teresa W.-M., Sun, Qiushi, Higashi, Richard M.
Publicado 2022

Purine nucleoside phosphorylase controls nicotinamide riboside metabolism in mammalian cells

por Kropotov, Andrey, Kulikova, Veronika, Solovjeva, Ljudmila, Yakimov, Alexander, Nerinovski, Kirill, Svetlova, Maria, Sudnitsyna, Julia, Plusnina, Alena, Antipova, Maria, Khodorkovskiy, Mikhail, Migaud, Marie E., Gambaryan, Stepan, Ziegler, Mathias, Nikiforov, Andrey
Publicado 2022