Dimers of D76N-β(2)-microglobulin display potent antiamyloid aggregation activity

por Maya-Martinez, Roberto, Xu, Yong, Guthertz, Nicolas, Walko, Martin, Karamanos, Theodoros K., Sobott, Frank, Breeze, Alexander L., Radford, Sheena E.
Publicado 2022

A noncanonical RNA-binding domain of the fragile X protein, FMRP, elicits translational repression independent of mRNA G-quadruplexes

por Scarpitti, MaKenzie R., Warrick, Julia E., Yoder, Evelyn L., Kearse, Michael G.
Publicado 2022

Unusual reactivity of a flavin in a bifurcating electron-transferring flavoprotein leads to flavin modification and a charge-transfer complex

por Mohamed-Raseek, Nishya, van Galen, Cornelius, Stanley, Robert, Miller, Anne-Frances
Publicado 2022

Red Blood Cells Protein Profile Is Modified in Breast Cancer Patients

por Pereira-Veiga, Thais, Bravo, Susana, Gómez-Tato, Antonio, Yáñez-Gómez, Celso, Abuín, Carmen, Varela, Vanesa, Cueva, Juan, Palacios, Patricia, Dávila-Ibáñez, Ana B., Piñeiro, Roberto, Vilar, Ana, Chantada-Vázquez, María del Pilar, López-López, Rafael, Costa, Clotilde
Publicado 2022

Reanalysis of ProteomicsDB Using an Accurate, Sensitive, and Scalable False Discovery Rate Estimation Approach for Protein Groups

por The, Matthew, Samaras, Patroklos, Kuster, Bernhard, Wilhelm, Mathias
Publicado 2022

Disruption of the glucagon receptor increases glucagon expression beyond α-cell hyperplasia in zebrafish

por Kang, Qi, Zheng, Jihong, Jia, Jianxin, Xu, Ying, Bai, Xuanxuan, Chen, Xinhua, Zhang, Xiao-Kun, Wong, F. Susan, Zhang, Chao, Li, Mingyu
Publicado 2022

HDL Isolated by Immunoaffinity, Ultracentrifugation, or Precipitation is Compositionally and Functionally Distinct

por Holzer, Michael, Ljubojevic-Holzer, Senka, Souza Junior, Douglas Ricardo, Stadler, Julia T., Rani, Alankrita, Scharnagl, Hubert, Ronsein, Graziella Eliza, Marsche, Gunther
Publicado 2022

Suppression of amyloid-β fibril growth by drug-engineered polymorph transformation

por Mafimoghaddam, Sima, Xu, Yuechuan, Sherman, Michael B., Orlova, Elena V., Karki, Prashant, Orman, Mehmet A., Vekilov, Peter G.
Publicado 2022

Molecular simulation of lignin-related aromatic compound permeation through gram-negative bacterial outer membranes

por Vermaas, Josh V., Crowley, Michael F., Beckham, Gregg T.
Publicado 2022

Essential roles of the cytokine oncostatin M in crosstalk between muscle fibers and immune cells in skeletal muscle after aerobic exercise

por Komori, Tadasuke, Morikawa, Yoshihiro
Publicado 2022

inSPIRE: An Open-Source Tool for Increased Mass Spectrometry Identification Rates Using Prosit Spectral Prediction

por Cormican, John A., Horokhovskyi, Yehor, Soh, Wai Tuck, Mishto, Michele, Liepe, Juliane
Publicado 2022

Macromolecular crowding amplifies allosteric regulation of T-cell protein tyrosine phosphatase

por Tun, May Thwe, Yang, Shen, Forti, Fabio Luis, Santelli, Eugenio, Bottini, Nunzio
Publicado 2022

Antidiabetic drug metformin suppresses tumorigenesis through inhibition of mevalonate pathway enzyme HMGCS1

por Chen, Yiyan, Li, Min, Yang, Yanying, Lu, Yan, Li, Xiaoying
Publicado 2022

Residues forming the gating regions of asymmetric multidrug transporter Pdr5 also play roles in conformational switching and protein folding

por Alhumaidi, Maryam, Nentwig, Lea-Marie, Rahman, Hadiar, Schmitt, Lutz, Rudrow, Andrew, Harris, Andrzej, Dillon, Cierra, Restrepo, Lucas, Lamping, Erwin, Arya, Nidhi, Ambudkar, Suresh V., Choy, John S., Golin, John
Publicado 2022

MITF is a novel transcriptional regulator of the calcium sensor STIM1: Significance in physiological melanogenesis

por Tanwar, Jyoti, Sharma, Akshay, Saurav, Suman, Shyamveer, Jatana, Nidhi, Motiani, Rajender K.
Publicado 2022

Differential contributions of the proteasome, autophagy, and chaperones to the clearance of arsenite-induced protein aggregates in yeast

por Hua, Sansan, Kłosowska, Agnieszka, Rodrigues, Joana I., Petelski, Gabriel, Esquembre, Lidia A., Lorentzon, Emma, Olsen, Lars F., Liberek, Krzysztof, Tamás, Markus J.
Publicado 2022

Phosphatidylserine exposure modulates adhesion GPCR BAI1 (ADGRB1) signaling activity

por Lala, Trisha, Doan, Juleva K., Takatsu, Hiroyuki, Hartzell, H. Criss, Shin, Hye-Won, Hall, Randy A.
Publicado 2022

Tryptophan mutations in G3BP1 tune the stability of a cellular signaling hub by weakening transient interactions with Caprin1 and USP10

por Sheehan, Colin T., Hampton, Thomas H., Madden, Dean R.
Publicado 2022

Ornate, large, extremophilic (OLE) RNA forms a kink turn necessary for OapC protein recognition and RNA function

por Lyon, Seth E., Harris, Kimberly A., Odzer, Nicole B., Wilkins, Sarah G., Breaker, Ronald R.
Publicado 2022

Identification of an E3 ligase that targets the catalytic subunit of RNA Polymerase I upon transcription stress

por Pitts, Stephanie, Liu, Hester, Ibrahim, Adel, Garg, Amit, Felgueira, Catarina Mendes, Begum, Asma, Fan, Wenjun, Teh, Selina, Low, Jin-Yih, Ford, Brittany, Schneider, David A., Hay, Ronald, Laiho, Marikki
Publicado 2022