Molecular basis for the recruitment of the Rab effector protein WDR44 by the GTPase Rab11

por Thibodeau, Matthew C., Harris, Noah J., Jenkins, Meredith L., Parson, Matthew A.H., Evans, John T., Scott, Mackenzie K., Shaw, Alexandria L., Pokorný, Daniel, Leonard, Thomas A., Burke, John E.
Publicado 2022

Free fatty acids stabilize integrin β(1)via S-nitrosylation to promote monocyte–endothelial adhesion

por Yao, Qinyu, Cui, Qi, Liu, Jia, Xie, Xinya, Jiang, Tingting, Wang, Haodong, Zhao, Ziwei, Zhao, Wenfei, Du, Xiong, Lai, Baochang, Xiao, Lei, Wang, Nanping
Publicado 2022

Mapping the KRAS proteoform landscape in colorectal cancer identifies truncated KRAS4B that decreases MAPK signaling

por Adams, Lauren M., DeHart, Caroline J., Drown, Bryon S., Anderson, Lissa C., Bocik, William, Boja, Emily S., Hiltke, Tara M., Hendrickson, Christopher L., Rodriguez, Henry, Caldwell, Michael, Vafabakhsh, Reza, Kelleher, Neil L.
Publicado 2022

An evolutionarily conserved N-terminal leucine is essential for MX1 GTPase antiviral activity against different families of RNA viruses

por McKellar, Joe, Arnaud-Arnould, Mary, Chaloin, Laurent, Tauziet, Marine, Arpin-André, Charlotte, Pourcelot, Oriane, Blaise, Mickaël, Moncorgé, Olivier, Goujon, Caroline
Publicado 2022

The crystal structure of the EspB-EspK virulence factor-chaperone complex suggests an additional type VII secretion mechanism in Mycobacterium tuberculosis

por Gijsbers, Abril, Eymery, Mathias, Gao, Ye, Menart, Isabella, Vinciauskaite, Vanesa, Siliqi, Dritan, Peters, Peter J., McCarthy, Andrew, Ravelli, Raimond B.G.
Publicado 2022

Identification, binding, and structural characterization of single domain anti-PD-L1 antibodies inhibitory of immune regulatory proteins PD-1 and CD80

por Kang-Pettinger, Tara, Walker, Kayleigh, Brown, Richard, Cowan, Richard, Wright, Helena, Baravalle, Roberta, Waters, Lorna C., Muskett, Frederick W., Bowler, Matthew W., Sawmynaden, Kovilen, Coombs, Peter J., Carr, Mark D., Hall, Gareth
Publicado 2022

Proteomics Investigation of Diverse Serological Patterns in COVID-19

por Liang, Xiao, Sun, Rui, Wang, Jing, Zhou, Kai, Li, Jun, Chen, Shiyong, Lyu, Mengge, Li, Sainan, Xue, Zhangzhi, Shi, Yingqiu, Xie, Yuting, Zhang, Qiushi, Yi, Xiao, Pan, Juan, Wang, Donglian, Xu, Jiaqin, Zhu, Hongguo, Zhu, Guangjun, Zhu, Jiansheng, Zhu, Yi, Zheng, Yufen, Shen, Bo, Guo, Tiannan
Publicado 2023

The AF-2 cofactor binding region is key for the selective SUMOylation of estrogen receptor alpha by antiestrogens

por Vallet, Amandine, El Ezzy, Mohamed, Diennet, Marine, Haidar, Salwa, Bouvier, Michel, Mader, Sylvie
Publicado 2022

Flotillin-2 regulates epidermal growth factor receptor activation, degradation by Cbl-mediated ubiquitination, and cancer growth

por Wisniewski, David J., Liyasova, Mariya S., Korrapati, Soumya, Zhang, Xu, Ratnayake, Shashikala, Chen, Qingrong, Gilbert, Samuel F., Catalano, Alexis, Voeller, Donna, Meerzaman, Daoud, Guha, Udayan, Porat-Shliom, Natalie, Annunziata, Christina M., Lipkowitz, Stanley
Publicado 2022

Phosphatidylinositol (3,5)-bisphosphate machinery regulates neurite thickness through neuron-specific endosomal protein NSG1/NEEP21

por Qi, Lijuan, Sun, Chen, Sun, Shenqing, Li, Aiqing, Hu, Qiuming, Liu, Yaobo, Zhang, Yanling
Publicado 2022

Surface electrostatics dictate RNA-binding protein CAPRIN1 condensate concentration and hydrodynamic properties

por Toyama, Yuki, Rangadurai, Atul Kaushik, Forman-Kay, Julie D., Kay, Lewis E.
Publicado 2022

RNA-binding protein LIN28A upregulates transcription factor HIF1α by posttranscriptional regulation via direct binding to UGAU motifs

por Yamamoto, Hiroto, Uchida, Yutaro, Kurimoto, Ryota, Chiba, Tomoki, Matsushima, Takahide, Ito, Yoshiaki, Inotsume, Maiko, Miyata, Kohei, Watanabe, Kenta, Inada, Masaki, Goshima, Naoki, Uchida, Tokujiro, Asahara, Hiroshi
Publicado 2022

An Optimized Proteomics Approach Reveals Novel Alternative Proteins in Mouse Liver Development

por Yang, Ying, Wang, Hongwei, Zhang, Yuanliang, Chen, Lei, Chen, Gennong, Bao, Zhaoshi, Yang, Yang, Xie, Zhi, Zhao, Qian
Publicado 2022

The SDBC is active in quenching oxidative conditions and bridges the cell envelope layers in Deinococcus radiodurans

por Farci, Domenica, Graça, André T., Iesu, Luca, de Sanctis, Daniele, Piano, Dario
Publicado 2022

Nuclear factor Nrf2 promotes glycosidase OGG1 expression by activating the AKT pathway to enhance leukemia cell resistance to cytarabine

por Shang, Qin, Pan, Chengyun, Zhang, Xi, Yang, Tonghua, Hu, Tianzhen, Zheng, Lin, Cao, Shuyun, Feng, Cheng, Hu, Xiuying, Chai, Xiao, Wang, Jishi, Fang, Qin
Publicado 2022

The structure of caseinolytic protease subunit ClpP2 reveals a functional model of the caseinolytic protease system from Chlamydia trachomatis

por Azadmanesh, Jahaun, Seleem, Mohamed A., Struble, Lucas, Wood, Nicholas A., Fisher, Derek J., Lovelace, Jeffrey J., Artigues, Antonio, Fenton, Aron W., Borgstahl, Gloria E.O., Ouellette, Scot P., Conda-Sheridan, Martin
Publicado 2022

Proteomic Profiling Reveals the Molecular Control of Oocyte Maturation

por Sun, Hongzheng, Sun, Guangyi, Zhang, Haotian, An, Huiqing, Guo, Yueshuai, Ge, Juan, Han, Longsen, Zhu, Shuai, Tang, Shoubin, Li, Congyang, Xu, Chen, Guo, Xuejiang, Wang, Qiang
Publicado 2022

Leucine 434 is essential for docosahexaenoic acid–induced augmentation of L-glutamate transporter current

por Takahashi, Kanako, Chen, Luying, Sayama, Misa, Wu, Mian, Hayashi, Mariko Kato, Irie, Tomohiko, Ohwada, Tomohiko, Sato, Kaoru
Publicado 2022

Proteomics analysis uncovers plasminogen activator PLAU as a target of the STING pathway for suppression of cancer cell migration and invasion

por Tan, Jingmin, Ge, Yangyang, Zhang, Meiting, Ding, Ming
Publicado 2022

Six-Transmembrane Epithelial Antigen of Prostate 3 Promotes Hepatic Insulin Resistance and Steatosis

por Ding, Ting, Chen, Siping, Xiao, Wenchang, Liu, Zhen, Tu, Jun, Yu, Yongjie, Dong, Bizhen, Chen, Wenping, Zeng, Yong
Publicado 2022