Limb blastema formation: How much do we know at a genetic and epigenetic level?

por Min, Sangwon, Whited, Jessica L.
Publicado 2022

Native Size-Exclusion Chromatography–Based Mass Spectrometry Reveals New Components of the Early Heat Shock Protein 90 Inhibition Response Among Limited Global Changes

por Samant, Rahul S., Batista, Silvia, Larance, Mark, Ozer, Bugra, Milton, Christopher I., Bludau, Isabell, Wu, Estelle, Biggins, Laura, Andrews, Simon, Hervieu, Alexia, Johnston, Harvey E., Al-Lazikhani, Bissan, Lamond, Angus I., Clarke, Paul A., Workman, Paul
Publicado 2022

Measurement of FGFR3 signaling at the cell membrane via total internal reflection fluorescence microscopy to compare the activation of FGFR3 mutants

por Hartl, Ingrid, Brumovska, Veronika, Striedner, Yasmin, Yasari, Atena, Schütz, Gerhard J., Sevcsik, Eva, Tiemann-Boege, Irene
Publicado 2022

The tetraspanin transmembrane protein CD53 mediates dyslipidemia and integrates inflammatory and metabolic signaling in hepatocytes

por Higgins, Cassandra B., Adams, Joshua A., Ward, Matthew H., Greenberg, Zev J., Milewska, Małgorzata, Sun, Jiameng, Zhang, Yiming, Chiquetto Paracatu, Luana, Dong, Qian, Ballentine, Samuel, Li, Weikai, Wandzik, Ilona, Schuettpelz, Laura G., DeBosch, Brian J.
Publicado 2022

αβ T-cell receptor recognition of self-phosphatidylinositol presented by CD1b

por Farquhar, Rachel, Van Rhijn, Ildiko, Moody, D. Branch, Rossjohn, Jamie, Shahine, Adam
Publicado 2022

5-Formyltetrahydrofolate promotes conformational remodeling in a methylenetetrahydrofolate reductase active site and inhibits its activity

por Yamada, Kazuhiro, Mendoza, Johnny, Koutmos, Markos
Publicado 2022

The main protease of SARS-CoV-2 cleaves histone deacetylases and DCP1A, attenuating the immune defense of the interferon-stimulated genes

por Song, Liu, Wang, Dianbing, Abbas, Ghulam, Li, Min, Cui, Mengmeng, Wang, Jufang, Lin, Zhanglin, Zhang, Xian-En
Publicado 2023

Structural basis of nirmatrelvir and ensitrelvir activity against naturally occurring polymorphisms of the SARS-CoV-2 main protease

por Noske, Gabriela Dias, de Souza Silva, Ellen, de Godoy, Mariana Ortiz, Dolci, Isabela, Fernandes, Rafaela Sachetto, Guido, Rafael Victório Carvalho, Sjö, Peter, Oliva, Glaucius, Godoy, Andre Schutzer
Publicado 2023

Resistin, Elastase, and Lactoferrin as Potential Plasma Biomarkers of Pediatric Inflammatory Bowel Disease Based on Comprehensive Proteomic Screens

por Louis Sam Titus, Anto Sam Crosslee, Vanarsa, Kamala, Soomro, Sanam, Patel, Anjali, Prince, Jarod, Kugathasan, Subra, Mohan, Chandra
Publicado 2022

Profiling Humoral Immunity After Mixing and Matching COVID-19 Vaccines Using SARS-CoV-2 Variant Protein Microarrays

por Kuo, Ho-Chang, Kuo, Kuang-Che, Du, Pin-Xian, Keskin, Batuhan Birol, Su, Wen-Yu, Ho, Tzong-Shiann, Tsai, Pei-Shan, Pau, Chi Ho, Shih, Hsi-Chang, Huang, Ying-Hsien, Weng, Ken-Pen, Syu, Guan-Da
Publicado 2023

Whole-genome CRISPR screening identifies PI3K/AKT as a downstream component of the oncogenic GNAQ–focal adhesion kinase signaling circuitry

por Arang, Nadia, Lubrano, Simone, Rigiracciolo, Damiano Cosimo, Nachmanson, Daniela, Lippman, Scott M., Mali, Prashant, Harismendy, Olivier, Gutkind, J. Silvio
Publicado 2022

Phosphorylation alters the mechanical stiffness of a model fragment of the dystrophin homologue utrophin

por Ramirez, Maria Paz, Rajaganapathy, Sivaraman, Hagerty, Anthony R., Hua, Cailong, Baxter, Gloria C., Vavra, Joseph, Gordon, Wendy R., Muretta, Joseph M., Salapaka, Murti V., Ervasti, James M.
Publicado 2022

Monitoring mitochondrial translation by pulse SILAC

por Imami, Koshi, Selbach, Matthias, Ishihama, Yasushi
Publicado 2023

The store-operated Ca(2+) channel Orai1α is required for agonist-evoked NF-κB activation by a mechanism dependent on PKCβ2

por Nieto-Felipe, Joel, Sanchez-Collado, Jose, Jardin, Isaac, Salido, Gines M., Lopez, Jose J., Rosado, Juan A.
Publicado 2023

Dynamic cycling with a unique Hsp90/Hsp70-dependent chaperone machinery and GAPDH is needed for heme insertion and activation of neuronal NO synthase

por Morishima, Yoshihiro, Lau, Miranda, Pratt, William B., Osawa, Yoichi
Publicado 2022

The penultimate step of proteasomal ATPase assembly is mediated by a switch dependent on the chaperone Nas2

por Sekaran, Suganya, Park, Soyeon
Publicado 2023

Combined inhibition of aurora kinases and Bcl-xL induces apoptosis through select BH3-only proteins

por Li, Jian, Chen, Cheng-Hsun, O’Neill, Katelyn L., Fousek-Schuller, Valerie J., Black, Adrian R., Black, Jennifer D., Zhang, Jingjing, Luo, Xu
Publicado 2023

Membrane skeleton hyperstability due to a novel alternatively spliced 4.1R can account for ellipsoidal camelid red cells with decreased deformability

por Chen, Yuqi, Miyazono, Kosuke, Otsuka, Yayoi, Kanamori, Mariko, Yamashita, Aozora, Arashiki, Nobuto, Matsumoto, Takehisa, Takada, Kensuke, Sato, Kota, Mohandas, Narla, Inaba, Mutsumi
Publicado 2023

Evolution of Rev7 interactions in eukaryotic TLS DNA polymerase Polζ

por McPherson, Kerry Silva, Rizzo, Alessandro A., Erlandsen, Heidi, Chatterjee, Nimrat, Walker, Graham C., Korzhnev, Dmitry M.
Publicado 2022

Kinetochore-microtubule attachment in human cells is regulated by the interaction of a conserved motif of Ska1 with EB1

por Radhakrishnan, Renjith M., Kizhakkeduth, Safwa T., Nair, Vishnu M., Ayyappan, Shine, Lakshmi, R. Bhagya, Babu, Neethu, Prasannajith, Anjaly, Umeda, Kenichi, Vijayan, Vinesh, Kodera, Noriyuki, Manna, Tapas K.
Publicado 2022