Spatially Resolved Top-Down Proteomics of Tissue Sections Based on a Microfluidic Nanodroplet Sample Preparation Platform

por Liao, Yen-Chen, Fulcher, James M., Degnan, David J., Williams, Sarah M., Bramer, Lisa M., Veličković, Dušan, Zemaitis, Kevin J., Veličković, Marija, Sontag, Ryan L., Moore, Ronald J., Paša-Tolić, Ljiljana, Zhu, Ying, Zhou, Mowei
Publicado 2023

Sec61 channel subunit Sbh1/Sec61β promotes ER translocation of proteins with suboptimal targeting sequences and is fine-tuned by phosphorylation

por Barbieri, Guido, Simon, Julien, Lupusella, Cristina R., Pereira, Fabio, Elia, Francesco, Meyer, Hadar, Schuldiner, Maya, Hanes, Steven D., Nguyen, Duy, Helms, Volkhard, Römisch, Karin
Publicado 2023

Pseudophosphorylation of Arabidopsis jasmonate biosynthesis enzyme lipoxygenase 2 via mutation of Ser(600) inhibits enzyme activity

por Kaur, Diljot, Dorion, Sonia, Jmii, Souleimen, Cappadocia, Laurent, Bede, Jacqueline C., Rivoal, Jean
Publicado 2023

MceG stabilizes the Mce1 and Mce4 transporters in Mycobacterium tuberculosis

por Fieweger, Rachael A., Wilburn, Kaley M., Montague, Christine R., Roszkowski, Emma K., Kelly, Carolyn M., Southard, Teresa L., Sondermann, Holger, Nazarova, Evgeniya V., VanderVen, Brian C.
Publicado 2023

Goldilocks calcium concentrations and the regulation of oxidative phosphorylation: Too much, too little, or just right

por Vilas-Boas, Eloisa A., Cabral-Costa, João Victor, Ramos, Vitor M., Caldeira da Silva, Camille C., Kowaltowski, Alicia J.
Publicado 2023

TEAD Proteins Associate With DNA Repair Proteins to Facilitate Cellular Recovery From DNA Damage

por Calses, Philamer C., Pham, Victoria C., Guarnaccia, Alissa D., Choi, Meena, Verschueren, Erik, Bakker, Sietske T., Pham, Trang H., Hinkle, Trent, Liu, Chad, Chang, Matthew T., Kljavin, Noelyn, Bakalarski, Corey, Haley, Benjamin, Zou, Jianing, Yan, Cuicui, Song, Xia, Lin, Xiaoyan, Rowntree, Rebecca, Ashworth, Alan, Dey, Anwesha, Lill, Jennie R.
Publicado 2023

In-Cell Chemical Crosslinking Identifies Hotspots for SQSTM-1/p62-IκBα Interaction That Underscore a Critical Role of p62 in Limiting NF-κB Activation Through IκBα Stabilization...

por Liu, Yi, Trnka, Michael J., He, Liang, Burlingame, A.L., Correia, Maria Almira
Publicado 2023

A “biphasic glycosyltransferase high-throughput screen” identifies novel anthraquinone glycosides in the diversification of phenolic natural products

por Mohideen, F. Ifthiha, Kwan, David H.
Publicado 2023

Ectopic RING activity at the ER membrane differentially impacts ERAD protein quality control pathways

por Mehrtash, Adrian B., Hochstrasser, Mark
Publicado 2023

Analysis of mammalian circadian clock protein complexes over a circadian cycle

por Cao, Xuemei, Wang, Li, Selby, Christopher P., Lindsey-Boltz, Laura A., Sancar, Aziz
Publicado 2023

Protein tyrosine phosphatase 69D is a substrate of protein O-mannosyltransferases 1-2 that is required for the wiring of sensory axons in Drosophila

por Monagas-Valentin, Pedro, Bridger, Robert, Chandel, Ishita, Koff, Melissa, Novikov, Boris, Schroeder, Patrick, Wells, Lance, Panin, Vladislav
Publicado 2023

Inositol pyrophosphate profiling reveals regulatory roles of IP6K2-dependent enhanced IP(7) metabolism in the enteric nervous system

por Ito, Masatoshi, Fujii, Natsuko, Kohara, Saori, Hori, Shuho, Tanaka, Masayuki, Wittwer, Christopher, Kikuchi, Kenta, Iijima, Takatoshi, Kakimoto, Yu, Hirabayashi, Kenichi, Kurotaki, Daisuke, Jessen, Henning J., Saiardi, Adolfo, Nagata, Eiichiro
Publicado 2023

Long-chain polyunsaturated lipids associated with responsiveness to anti-PD-1 therapy are colocalized with immune infiltrates in the tumor microenvironment

por King, Mary E., Yuan, Robert, Chen, Jeremy, Pradhan, Komal, Sariol, Isabel, Li, Shirley, Chakraborty, Ashish, Ekpenyong, Oscar, Yearley, Jennifer H., Wong, Janica C., Zúñiga, Luis, Tomazela, Daniela, Beaumont, Maribel, Han, Jin-Hwan, Eberlin, Livia S.
Publicado 2023

Mass spectrometry imaging–based assays for aminotransferase activity reveal a broad substrate spectrum for a previously uncharacterized enzyme

por de Raad, Markus, Koper, Kaan, Deng, Kai, Bowen, Benjamin P., Maeda, Hiroshi A., Northen, Trent R.
Publicado 2023

The mTORC1–G9a–H3K9me2 axis negatively regulates autophagy in fatty acid–induced hepatocellular lipotoxicity

por Mushtaq, Arjamand, Ashraf, Nissar Ul, Altaf, Mohammad
Publicado 2023

Molecular engineering of a minimal E-cadherin inhibitor protein derived from Clostridium botulinum hemagglutinin

por Amatsu, Sho, Matsumura, Takuhiro, Zuka, Masahiko, Fujinaga, Yukako
Publicado 2023

Striking membrane defects in AdipoR-deficient cells

por Ruiz, Mario, Panagaki, Dimitra, Höög, Johanna L., Pilon, Marc
Publicado 2023

Structural insights into the recognition of telomeric variant repeat TTGGGG by broad-complex, tramtrack and bric-à-brac - zinc finger protein ZBTB10

por Wang, Suman, Xu, Ziyan, Li, Meili, Lv, Mengqi, Shen, Siyuan, Shi, Yunyu, Li, Fudong
Publicado 2023

Complex interaction network revealed by mutation of human telomerase ‘insertion in fingers’ and essential N-terminal domains and the telomere protein TPP1

por Lambert-Lanteigne, Patrick, Young, Adrian, Autexier, Chantal
Publicado 2023

Capture, Release, and Identification of Newly Synthesized Proteins for Improved Profiling of Functional Translatomes

por Phillips, Nancy J., Vinaithirthan, Bala M., Oses-Prieto, Juan A., Chalkley, Robert J., Burlingame, Alma L.
Publicado 2023