The intriguing molecular dynamics of Cer[EOS] in rigid skin barrier lipid layers requires improvement of the model

por Fandrei, Ferdinand, Havrišák, Tomáš, Opálka, Lukáš, Engberg, Oskar, Smith, Albert A., Pullmannová, Petra, Kučerka, Norbert, Ondrejčeková, Veronika, Demé, Bruno, Nováková, Lucie, Steinhart, Miloš, Vávrová, Kateřina, Huster, Daniel
Publicado 2023

The origin of long-chain fatty acids required for de novo ether lipid/plasmalogen synthesis

por Chornyi, Serhii, Ofman, Rob, Koster, Janet, Waterham, Hans R.
Publicado 2023

Kinetic analysis of RNA cleavage by coronavirus Nsp15 endonuclease: Evidence for acid–base catalysis and substrate-dependent metal ion activation

por Huang, Tong, Snell, Kimberly C., Kalia, Nidhi, Gardezi, Shahbaz, Guo, Lily, Harris, Michael E.
Publicado 2023

An affinity tool for the isolation of endogenous active mTORC1 from various cellular sources

por Ibrahim, Yasir H., Pantelios, Spyridon, Mutvei, Anders P.
Publicado 2023

The ups and downs of Pax6 in neural stem cells

por Shohayeb, Belal, Cooper, Helen M.
Publicado 2023

Glycocalyx engineering with heparan sulfate mimetics attenuates Wnt activity during adipogenesis to promote glucose uptake and metabolism

por Trieger, Greg W., Pessentheiner, Ariane R., Purcell, Sean C., Green, Courtney R., DeForest, Natalie, Willert, Karl, Majithia, Amit R., Metallo, Christian M., Godula, Kamil, Gordts, Philip L.S.M.
Publicado 2023

Different transmembrane domains determine the specificity and efficiency of the cleavage activity of the γ-secretase subunit presenilin

por Schmidt, Fabian C., Fitz, Katja, Feilen, Lukas P., Okochi, Masayasu, Steiner, Harald, Langosch, Dieter
Publicado 2023

Identification of nonhistone substrates of the lysine methyltransferase PRDM9

por Hanquier, Jocelyne N., Sanders, Kenidi, Berryhill, Christine A., Sahoo, Firoj K., Hudmon, Andy, Vilseck, Jonah Z., Cornett, Evan M.
Publicado 2023

The stem cell–supporting small molecule UM171 triggers Cul3-KBTBD4–mediated degradation of ELM2 domain–harboring proteins

por Žemaitis, Kristijonas, Ghosh, Sudip, Hansson, Jenny, Subramaniam, Agatheeswaran
Publicado 2023

Detection of Nα-terminally formylated native proteins by a pan-N-formyl methionine-specific antibody

por Kim, Dasom, Seok, Ok-Hee, Ju, Shinyeong, Kim, Sang-Yoon, Kim, Jeong-Mok, Lee, Cheolju, Hwang, Cheol-Sang
Publicado 2023

High sensitivity and low-cost flavin luciferase (FLUX(Vc))-based reporter gene for mammalian cell expression

por Phonbuppha, Jittima, Tinikul, Ruchanok, Ohmiya, Yoshihiro, Chaiyen, Pimchai
Publicado 2023

The intramembrane COOH-terminal domain of PRRT2 regulates voltage-dependent Na(+) channels

por Franchi, Francesca, Marte, Antonella, Corradi, Beatrice, Sterlini, Bruno, Alberini, Giulio, Romei, Alessandra, De Fusco, Antonio, Vogel, Alexander, Maragliano, Luca, Baldelli, Pietro, Corradi, Anna, Valente, Pierluigi, Benfenati, Fabio
Publicado 2023

Exploration of O-GlcNAc transferase glycosylation sites reveals a target sequence compositional bias

por Chong, P. Andrew, Nosella, Michael L., Vanama, Manasvi, Ruiz-Arduengo, Roxana, Forman-Kay, Julie D.
Publicado 2023

The Wnt pathway protein Dvl1 targets somatostatin receptor 2 for lysosome-dependent degradation

por Carr, Heather S., Zuo, Yan, Frost, Jeffrey A.
Publicado 2023

eIF3d: A driver of noncanonical cap–dependent translation of specific mRNAs and a trigger of biological/pathological processes

por Ma, Shijie, Liu, Jing-Yuan, Zhang, Jian-Ting
Publicado 2023

TRIM28 negatively regulates the RLR signaling pathway by targeting MAVS for degradation via K48-linked polyubiquitination

por Chen, Ya-Yun, Ran, Xiang-Hong, Ni, Run-Ze, Mu, Dan
Publicado 2023

Itch receptor MRGPRX4 interacts with the receptor activity–modifying proteins

por Kotliar, Ilana B., Ceraudo, Emilie, Kemelmakher-Liben, Kevin, Oren, Deena A., Lorenzen, Emily, Dodig-Crnković, Tea, Horioka-Duplix, Mizuho, Huber, Thomas, Schwenk, Jochen M., Sakmar, Thomas P.
Publicado 2023

A thermosensitive PCNA allele underlies an ataxia-telangiectasia-like disorder

por Magrino, Joseph, Munford, Veridiana, Martins, Davi Jardim, Homma, Thais K., Page, Brendan, Gaubitz, Christl, Freire, Bruna L., Lerario, Antonio M., Vilar, Juliana Brandstetter, Amorin, Antonio, Leão, Emília K.E., Kok, Fernando, Menck, Carlos FM., Jorge, Alexander AL., Kelch, Brian A.
Publicado 2023

Serum amyloid A augments the atherogenic effects of cholesteryl ester transfer protein

por Ji, Ailing, Trumbauer, Andrea C., Noffsinger, Victoria P., de Beer, Frederick C., Webb, Nancy R., Tannock, Lisa R., Shridas, Preetha
Publicado 2023

Data-Independent Acquisition Phosphoproteomics of Urinary Extracellular Vesicles Enables Renal Cell Carcinoma Grade Differentiation

por Hadisurya, Marco, Lee, Zheng-Chi, Luo, Zhuojun, Zhang, Guiyuan, Ding, Yajie, Zhang, Hao, Iliuk, Anton B., Pili, Roberto, Boris, Ronald S., Tao, W. Andy
Publicado 2023