Short-term CaMKII inhibition with tatCN19o does not erase pre-formed memory in mice and is neuroprotective in pigs

por Rumian, Nicole L., Brown, Carolyn Nicole, Hendry-Hofer, Tara B., Rossetti, Thomas, Orfila, James E., Tullis, Jonathan E., Dwoskin, Linda P., Buonarati, Olivia R., Lisman, John E., Quillinan, Nidia, Herson, Paco S., Bebarta, Vikhyat S., Bayer, K. Ulrich
Publicado 2023

Antibody-guided proteases enable selective and catalytic degradation of challenging therapeutic targets

por Romei, Matthew G., Leonard, Brandon, Kim, Ingrid, Kim, Hok Seon, Lazar, Greg A.
Publicado 2023

Organizing the synaptic junctions

por Zhou, Qiangjun
Publicado 2023

Nascent MSKIK peptide cancels ribosomal stalling by arrest peptides in Escherichia coli

por Ojima-Kato, Teruyo, Nishikawa, Yuma, Furukawa, Yuki, Kojima, Takaaki, Nakano, Hideo
Publicado 2023

Rapid, scalable assay of amylin-β amyloid co-aggregation in brain tissue and blood

por Kotiya, Deepak, Leibold, Noah, Verma, Nirmal, Jicha, Gregory A., Goldstein, Larry B., Despa, Florin
Publicado 2023

The ubiquitin ligase HERC4 suppresses MafA transcriptional activity triggered by GSK3β in myeloma by atypical K63-linked polyubiquitination

por Zhang, Zubin, Li, Mei, Lin, Peng, Ren, Ying, He, Yuanming, Wang, Siyu, Xu, Yujia, Cao, Biyin, Wang, Guanghui, Moran, Michael F., Mao, Xinliang
Publicado 2023

The interplay of 3D genome organization with UV-induced DNA damage and repair

por Akköse, Ümit, Adebali, Ogün
Publicado 2023

The diverse effects of pathogenic point mutations on ion channel activity of a gain-of-function polycystin-2

por Wang, Yan, Wang, Zhifei, Pavel, Mahmud Arif, Ng, Courtney, Kashyap, Parul, Li, Bin, Morais, Tiago D.C., Ulloa, Gabriella A., Yu, Yong
Publicado 2023

Teaching an old dog new tricks: A new tool for protein tyrosine phosphatase substrate discovery

por Bennett, Anton M.
Publicado 2023

Neonatal and adult cardiac fibroblasts exhibit inherent differences in cardiac regenerative capacity

por Sun, Hualing, Pratt, Richard E., Dzau, Victor J., Hodgkinson, Conrad P.
Publicado 2023

Nonstructural N- and C-tails of Dbp2 confer the protein full helicase activities

por Song, Qin-Xia, Liu, Na-Nv, Liu, Zhao-Xia, Zhang, Ying-Zi, Rety, Stephane, Hou, Xi-Miao, Xi, Xu-Guang
Publicado 2023

Regulation of TREM2 expression by transcription factor YY1 and its protective effect against Alzheimer’s disease

por Lu, Yanhui, Huang, Xiaofeng, Liang, Wenping, Li, Yu, Xing, Mengen, Pan, Wenhao, Zhang, Yun, Wang, Zhe, Song, Weihong
Publicado 2023

A novel machine learning-based screening identifies statins as inhibitors of the calcium pump SERCA

por Cruz-Cortés, Carlos, Velasco-Saavedra, M. Andrés, Fernández-de Gortari, Eli, Guerrero-Serna, Guadalupe, Aguayo-Ortiz, Rodrigo, Espinoza-Fonseca, L. Michel
Publicado 2023

NOX4–TIM23 interaction regulates NOX4 mitochondrial import and metabolic reprogramming

por Pandey, Jyotsana, Larson-Casey, Jennifer L., Patil, Mallikarjun H., Joshi, Rutwij, Jiang, Chun-sun, Zhou, Yong, He, Chao, Carter, A. Brent
Publicado 2023

Relationship between hepatic and mitochondrial ceramides: a novel in vivo method to track ceramide synthesis

por Mucinski, Justine M., McCaffrey, Jonas M., Rector, R. Scott, Kasumov, Takhar, Parks, Elizabeth J.
Publicado 2023

Conserved regions of the regulatory subunit Spo7 are required for Nem1–Spo7/Pah1 phosphatase cascade function in yeast lipid synthesis

por Jog, Ruta, Han, Gil-Soo, Carman, George M.
Publicado 2023

ASTER-B regulates mitochondrial carotenoid transport and homeostasis

por Bandara, Sepalika, Moon, Jean, Ramkumar, Srinivasagan, von Lintig, Johannes
Publicado 2023

Diet-induced induction of hepatic serine/threonine kinase STK38 triggers proinflammation and hepatic lipid accumulation

por Rawat, Priya, Thakur, Shilpa, Dogra, Surbhi, Jaswal, Kajal, Dehury, Budheswar, Mondal, Prosenjit
Publicado 2023

eIF2α incites photoreceptor cell and retina damage by all-trans-retinal

por He, Danxue, Tao, Lei, Cai, Binxiang, Chen, Xiangjun, Wang, Yan, Li, Shiying, Liao, Chunyan, Chen, Yuling, Chen, Jingmeng, Liu, Zuguo, Wu, Yalin
Publicado 2023

FOX transcription factors are common regulators of Wnt/β-catenin–dependent gene transcription

por Moparthi, Lavanya, Koch, Stefan
Publicado 2023