Quantitative Proteomic Analysis Reveals apoE4-Dependent Phosphorylation of the Actin-Regulating Protein VASP

por Cakir, Zeynep, Lord, Samuel J., Zhou, Yuan, Jang, Gwendolyn M., Polacco, Benjamin J., Eckhardt, Manon, Jimenez-Morales, David, Newton, Billy W., Orr, Adam L., Johnson, Jeffrey R., da Cruz, Alexandre, Mullins, R. Dyche, Krogan, Nevan J., Mahley, Robert W., Swaney, Danielle L.
Publicado 2023

Deciphering the Clinical Significance and Kinase Functions of GSK3α in Colon Cancer by Proteomics and Phosphoproteomics

por Gao, Li, Lu, Ying, Chen, Hai-Ning, Li, Zhigui, Hu, Meng, Zhang, Rou, Wang, Xiuxuan, Xu, Zhiqiang, Gong, Yanqiu, Wang, Rui, Du, Dan, Hai, Shan, Li, Shuangqing, Su, Dan, Li, Yuan, Xu, Heng, Zhou, Zong-Guang, Dai, Lunzhi
Publicado 2023

Genome-wide contributions of the MutSα- and MutSβ-dependent DNA mismatch repair pathways to the maintenance of genetic stability in Saccharomyces cerevisiae

por Kadyrova, Lyudmila Y., Mieczkowski, Piotr A., Kadyrov, Farid A.
Publicado 2023

Oxygen modulates iron homeostasis by switching iron sensing of NCOA4

por Kuno, Sota, Iwai, Kazuhiro
Publicado 2023

PTEN-induced kinase PINK1 supports colorectal cancer growth by regulating the labile iron pool

por Chen, Brandon, Das, Nupur K., Talukder, Indrani, Singhal, Rashi, Castillo, Cristina, Andren, Anthony, Mancias, Joseph D., Lyssiotis, Costas A., Shah, Yatrik M.
Publicado 2023

MicroRNA-593-5p contributes to cell death following exposure to 1-methyl-4-phenylpyridinium by targeting PTEN-induced putative kinase 1

por Yoo, Myungsik, Choi, Doo Chul, Murphy, Aleta, Ahsan, Atiq M., Junn, Eunsung
Publicado 2023

Structural insights into the substrate recognition of serine palmitoyltransferase from Sphingobacterium multivorum

por Ikushiro, Hiroko, Murakami, Taiki, Takahashi, Aya, Katayama, Asuka, Sawai, Taiki, Goto, Haruna, Koolath, Sajeer, Murai, Yuta, Monde, Kenji, Miyahara, Ikuko, Kamiya, Nobuo, Yano, Takato
Publicado 2023

The dynamin Vps1 mediates Atg9 transport to the sites of autophagosome formation

por Arlt, Henning, Raman, Babu, Filali-Mouncef, Yasmina, Hu, Yan, Leytens, Alexandre, Hardenberg, Ralph, Guimarães, Rodrigo, Kriegenburg, Franziska, Mari, Muriel, Smaczynska-de Rooij, Iwona I., Ayscough, Kathryn R., Dengjel, Jörn, Ungermann, Christian, Reggiori, Fulvio
Publicado 2023

Cellular stress induces non-canonical activation of the receptor tyrosine kinase EphA2 through the p38-MK2-RSK signaling pathway

por Zhou, Yue, Oki, Ryota, Tanaka, Akihiro, Song, Leixin, Takashima, Atsushi, Hamada, Naru, Yokoyama, Satoru, Yano, Seiji, Sakurai, Hiroaki
Publicado 2023

Dephosphorylation of neural wiring protein shootin1 by PP1 phosphatase regulates netrin-1-induced axon guidance

por Kastian, Ria Fajarwati, Baba, Kentarou, Kaewkascholkul, Napol, Sasaki, Hisashi, Watanabe, Rikiya, Toriyama, Michinori, Inagaki, Naoyuki
Publicado 2023

Functional analysis of a conserved site mutation in the DNA end processing enzyme PNKP leading to ataxia with oculomotor apraxia type 4 in humans

por Islam, Azharul, Chakraborty, Anirban, Gambardella, Stefano, Campopiano, Rosa, Sarker, Altaf H., Boldogh, Istvan, Hazra, Tapas
Publicado 2023

An A-kinase anchoring protein (ACBD3) coordinates traffic-induced PKA activation at the Golgi

por Jia, Jie, Tang, Shuocheng, Yue, Xihua, Jing, Shuaiyang, Zhu, Lianhui, Tan, Chuanting, Gao, Jingkai, Du, Yulei, Lee, Intaek, Qian, Yi
Publicado 2023

Enzymatic comparison of two homologous enzymes reveals N-terminal domain of chondroitinase ABC I regulates substrate selection and product generation

por Du, Min, Wei, Lin, Yuan, Min, Zou, Ruyi, Xu, Yingying, Wang, Xu, Wang, Wenshuang, Li, Fuchuan
Publicado 2023

A New Cellular Interactome of SARS-CoV-2 Nucleocapsid Protein and Its Biological Implications

por Min, Yuan-Qin, Huang, Mengzhuo, Feng, Kuan, Jia, Yajie, Sun, Xiulian, Ning, Yun-Jia
Publicado 2023

Domain-specific modulatory effects of phosphomimetic substitutions on liquid-liquid phase separation of tau protein

por Boyko, Solomiia, Surewicz, Witold K.
Publicado 2023

Identification of a novel amphioxus leucine-rich repeat receptor involved in phagocytosis reveals a role for Slit2-N-type LRR in bacterial elimination

por Zhan, Yanli, Zhao, Chen-si, Qu, Xuemei, Xiao, Zhihui, Deng, Chong, Li, Yingqiu
Publicado 2023

N-Terminomic Changes in Neurons During Excitotoxicity Reveal Proteolytic Events Associated With Synaptic Dysfunctions and Potential Targets for Neuroprotection

por Ameen, S. Sadia, Griem-Krey, Nane, Dufour, Antoine, Hossain, M. Iqbal, Hoque, Ashfaqul, Sturgeon, Sharelle, Nandurkar, Harshal, Draxler, Dominik F., Medcalf, Robert L., Kamaruddin, Mohd Aizuddin, Lucet, Isabelle S., Leeming, Michael G., Liu, Dazhi, Dhillon, Amardeep, Lim, Jet Phey, Basheer, Faiza, Zhu, Hong-Jian, Bokhari, Laita, Roulston, Carli L., Paradkar, Prasad N., Kleifeld, Oded, Clarkson, Andrew N., Wellendorph, Petrine, Ciccotosto, Giuseppe D., Williamson, Nicholas A., Ang, Ching-Seng, Cheng, Heung-Chin
Publicado 2023

Reactive sulfur species disaggregate the SQSTM1/p62-based aggresome-like induced structures via the HSP70 induction and prevent parthanatos

por Yamada, Yutaro, Noguchi, Takuya, Suzuki, Midori, Yamada, Mayuka, Hirata, Yusuke, Matsuzawa, Atsushi
Publicado 2023

The ubiquitination status of the glucagon receptor determines signal bias

por Kaur, Suneet, Sokrat, Badr, Capozzi, Megan E., El, Kimberley, Bai, Yushi, Jazic, Aeva, Han, Bridgette, Krishna Kumar, Kaavya, D'Alessio, David A., Campbell, Jonathan E., Bouvier, Michel, Shenoy, Sudha K.
Publicado 2023

Stimulating β-adrenergic receptors promotes synaptic potentiation by switching CaMKII movement from LTD to LTP mode

por Larsen, Matthew E., Buonarati, Olivia R., Qian, Hai, Hell, Johannes W., Bayer, K. Ulrich
Publicado 2023